Understand the source comparison
19-Peptide Shelf Life Comparison Table
Molecular weight, amino acid composition, cyclic versus linear structure, and oxidation sensitivity all affect how long a reconstituted vial stays potent. All estimates below assume bacteriostatic water and refrigeration at 2-8°C. BPC-157 28-30 days 4-6 hours
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Molecular weight, amino acid composition, cyclic versus linear structure, and oxidation sensitivity all affect how long a reconstituted vial stays potent. All estimates below assume bacteriostatic water and refrigeration at 2-8°C.
- BPC-157
- 28-30 days
- 4-6 hours max
- Gastric acid resistant; unusually stable
- TB-500
- 43 amino acids; stable with gentle handling
- GHK-Cu
- 21-28 days
- 2-4 hours max
- Copper ion oxidizes; shorter shelf life
- Semaglutide
- 28-56 days
- Up to 56 days (pen)
- Pen formulations exceptionally stable
- Tirzepatide
- Up to 28 days (pen)
- Similar stability to semaglutide
- Ipamorelin
- Stable pentapeptide; standard handling
- CJC-1295
- DAC variant slightly more stable than no-DAC
- Sermorelin
- Standard GH secretagogue stability
- GHRP-6
- PT-141
- Cyclic structure adds stability
- Melanotan II
- 30-40 days
- 6-8 hours max
- Cyclic peptide; among the most stable after mixing
- Selank
- 14-21 days
- Often nasal spray; refrigerate after opening
- Semax
- Nasal spray form; same rules as Selank
- MOTS-c
- Mitochondrial peptide; light sensitive
- IGF-1 LR3
- 2-3 hours max
- pH sensitive; degrades faster than most
- NAD+
- 7-14 days
- 1-2 hours max
- Degrades rapidly in solution; use quickly
- Retatrutide
- Triple agonist; standard handling
- Epithalon
- Tetrapeptide; very stable small molecule
- Thymosin Alpha-1
- 28 amino acids; stable under standard conditions
- Cyclic peptides like PT-141 and Melanotan II last the longest. Their ring structure resists hydrolysis better than linear chains. Peptides with copper (GHK-Cu) or sensitive residues (IGF-1 LR3, NAD+) degrade faster.
- GLP-1 agonists like semaglutide and tirzepatide are engineered for stability, which is why prefilled pens tolerate weeks at room temperature. For full storage instructions covering both powder and liquid forms, see the peptide storage guide.