Guide library
Plain-language education with dates, authors and original source links where available.
Pfizer will apply Triana Biomedicines’ target-first and proximity-first discovery platform to discover molecular glue degraders for unspecified “multiple” targets in oncology and several other disease areas, t…
Read guide →Two studies published in recent weeks along with a pair of studies released over the past two years showcase pharma’s drift toward biologic development and provide evidence of the promise of large molecule dru…
Read guide →Demyelinating diseases are any conditions that damage the protective coating on nerve cells, the myelin sheath. Some common demyelinating diseases of the central nervous system include multiple sclerosis, neur…
Read guide →Novartis will apply Generate:Biomedicines’ generative artificial intelligence (AI) platform to discover and develop protein therapeutics for multiple unspecified disease areas, through a collaboration that cou…
Read guide →Targeted protein degraders (TPDs) are found in the lighter weight divisions of therapetuic development. But even though these therapeutic contenders qualify as small-molecule agents, they pack a big punch. Ind…
Read guide →A new murine study headed by a team at New York University has uncovered a biological explanation for our ability to retain memories over the long term. The discovery centers on the role of a molecule, KIBRA, …
Read guide →Predicting which proteins bind to each other, or protein-protein interactions, has been a challenge for methods based in computational biology. One of the reasons is primarily due to the vast diversity and com…
Read guide →- Time: In 2000, a LEAP-1 (liver expressed antimicrobial peptide) consisting of a 25 amino acid peptide was reported with unique antimicrobial activity. By 2001, three isoforms (20, 22, and 25 amino acids) of …
Read guide →Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that’s different from the white fat around our belly and thighs, and has a special job. Brown fat helps to convert the calori…
Read guide →March 15, 2007 (Vol. 27, No. 6) Company Develops New Approaches to Advancing its Technology Base Penguins have become celebrities, with real and animated versions starring in recent movies. But when several pe…
Read guide →Traumatic brain injury (TBI) –– defined as a bump, blow or jolt to the head that disrupts normal brain function –– sent 2.5 million people in the U.S. to the emergency room in 2014, according to statistics fro…
Read guide →Locations: Search AdvertisementAdvertisement Packed with iron, vitamin A and protein, beef liver provides a healthy low-calorie meat option Image content: This image is available to view online. View image onl…
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Read guide →An international research team led by the Medical University of Vienna has investigated a new peptide derived from cone snail venom which significantly reduced inflammation-induced pain in an animal model. Cru…
Read guide →Lipids are molecules that contain hydrocarbons and make up the building blocks of the structure and function of living cells. Examples of lipids include fats, oils, waxes, certain vitamins (such as A, D, E and…
Read guide →NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. Consumer Medicine Information (CMI) summary 1. Why am I using NOLVADEX? 2. What should I know before I use NOLVADEX…
Read guide →Locations: AdvertisementAdvertisement Keep it simple: Stick with a gentle cleanser, vitamin C, retinol, moisturizer and sunscreen Image content: This image is available to view online. View image online (https…
Read guide →Bioactive peptides are small protein fragments that promote metabolic health by exerting a positive influence on biological responses within the body. The therapeutic applications of these novel molecules incl…
Read guide →For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on resource-intensive e…
Read guide →For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it. Transcription factors are protein…
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