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Whey Protein Supplementation May Reduce Components of Metabolic Syndrome - Endocrinology Advisor

Whey protein supplementation significantly reduced metabolic syndrome components, according to literature review results published in Diabetes & Metabolic Syndrome. Specific components included systolic blood pressure, diastolic blood pressure, high-density li

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Whey protein supplementation significantly reduced metabolic syndrome components, according to literature review results published in Diabetes & Metabolic Syndrome. Specific components included systolic blood pressure, diastolic blood pressure, high-density lipoprotein cholesterol level, triglyceride level, fasting blood glucose level, and waist circumference.

Investigators searched PubMed, Scopus, Web of Science, and Cochrane Library for randomized controlled trials published between January 2000 and May 2019. Desired trial criteria included participants aged ≥18 years older who were overweight or obese; administration of interventions such as whey protein isolate, concentrate, extract, supplement, powder, and hydrolysate over a period of at least 2 weeks; and an outcome assessment of metabolic syndrome components.

The systemic review ultimately included 37 published articles with a total population of >2344 individuals. Pooled estimation results indicated that whey supplementation was associated with significant reductions in all 6 outcome categories (P <.001 for all): systolic blood pressure (weighted mean difference [WMD], -7.46; 95% CI, -9.39 to -6.13); diastolic blood pressure (WMD, -5.68; 95% CI, -6.69 to -4.67); high-density lipoprotein cholesterol level (WMD, -6.07; 95% CI, -7.53 to -4.61); triglyceride level (WMD, -18.19; 95% CI, -22.49 to -15.30); fasting blood glucose level (WMD, -1.42; 95% CI, -1.52 to -1.31); and waist circumference (WMD, -2.76; 95% CI, -3.83 to -1.69).

The researchers noted that there was significant heterogeneity between studies for each metabolic syndrome component (I2 range, 98.9%-100%).

“This study was carried out [to explore] the effect of whey protein on the components of metabolic syndrome in [patients with] overweight and obesity,” wrote the investigators.

They concluded that their results showed the “effective role of whey protein on metabolic syndrome,” but noted that results of some studies in the review were inconsistent with the pooled results, with data that showed no change in components of metabolic syndrome with whey supplementation.

Reference

Mustafa B, Mojtaba S, Mohammad S, Karim P, Taghdir M. The effect of whey protein on the components of metabolic syndrome in overweight and obese individuals; a systematic review and meta-analysis [published online November 15, 2019]. Diabetes Metab Syndr. doi:10.1016/j.dsx.2019.11.001

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Related questions

01Is whey protein concentrate the same thing as whey protein isolate?

Yes, with differences in protein and fat makeup. While both types are used in nutritional supplements, whey protein isolate typically has a higher percentage of protein content.

Source: www.everydayhealth.com ↗
02How does work?

Whey protein is a source of protein that might improve the nutrient content of the diet. Whey protein might also have effects on the immune system.

Source: www.rxlist.com ↗
03Does Whey Protein Elevate Your Uric Acid?

Whey protein is a type of nutritional supplement made from cow’s milk. Athletes use it to aid muscle recovery following intense bouts of resistance training. Whey is also promoted as a general health supplement to help prevent or correct a protein deficiency in your diet. Whey protein is not associated with elevated uric acid levels.

Source: www.everydayhealth.com ↗
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A Comparison of Glutathione-Boosting Strategies

Whey is a powerful tool, but it's not the only one researchers and health optimizers use to target glutathione levels. It's helpful to see how it stacks up against other common methods. Our…

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What Does the Research Say?

Several studies support the combined use of creatine and whey protein: • A 2017 review in the Journal of the International Society of Sports Nutrition concluded that creatine plus protein supplementation led to greater gains in lean body mass and strength than protein alone.• Research published in Nutrients (2018) found that participants taking both creatine and whey protein experienced improved workout performance and recovery metrics.• A 2020 trial demonstrated that combining creatine with fast-digested proteins like whey resulted in higher muscle creatine retention compared to creatine taken with carbohydrates. Overall, the body of evidence suggests that "creatine and protein powder together" can have additive effects on muscle growth and performance.

Source: ubiehealth.com ↗
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