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Vichy Liftactiv Peptide-C Versus Olay Regenerist Ultra Rich Moisturizer

Vichy Liftactiv Peptide-C Versus Olay Regenerist Ultra Rich Moisturizer This anti-aging moisturizer is formulated around Adenosine and Ascorbyl Glucoside to soften the look of wrinkles and brighten dull-looking skin. This anti-aging day moisturizer is formulat

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Vichy Liftactiv Peptide-C Versus Olay Regenerist Ultra Rich Moisturizer

This anti-aging moisturizer is formulated around Adenosine and Ascorbyl Glucoside to soften the look of wrinkles and brighten dull-looking skin.

This anti-aging day moisturizer is formulated around Niacinamide and Palmitoyl Pentapeptide-4 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Isohexadecane

Alcohol Denat.

Silica

Hydroxyethylpiperazine Ethane Sulfonic Acid

Propanediol

Synthetic Wax

PEG-10 Dimethicone

Eperua Falcata Bark Extract

PEG-30 Dipolyhydroxystearate

Stearyl Alcohol

Sorbitan Oleate

Dimethicone/PEG-10/15 Crosspolymer

Dimethicone/Polyglycerin-3 Crosspolymer

Ceteareth-6

Sodium Acrylates Copolymer

Sodium Citrate

Sodium Hydroxide

Sodium Phytate

Cyclodextrin

Adenosine

Ascorbyl Glucoside

Nylon-12

Isopropyl Alcohol

Propylene Carbonate

Dipropylene Glycol

Caprylic/Capric Triglyceride

Caprylyl Glycol

Acetyl Tetrapeptide-9

Synthetic Fluorphlogopite

Disteardimonium Hectorite

Dextrin

Pisum Sativum Extract

Tocopherol

Phenoxyethanol

CI 15985

CI 77891

Parfum

Water, Glycerin, Dimethicone, Isohexadecane, Alcohol Denat., Silica, Hydroxyethylpiperazine Ethane Sulfonic Acid, Propanediol, Synthetic Wax, PEG-10 Dimethicone, Eperua Falcata Bark Extract, PEG-30 Dipolyhydroxystearate, Stearyl Alcohol, Sorbitan Oleate, Dimethicone/PEG-10/15 Crosspolymer, Dimethicone/Polyglycerin-3 Crosspolymer, Ceteareth-6, Sodium Acrylates Copolymer, Sodium Citrate, Sodium Hydroxide, Sodium Phytate, Cyclodextrin, Adenosine, Ascorbyl Glucoside, Nylon-12, Isopropyl Alcohol, Propylene Carbonate, Dipropylene Glycol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Acetyl Tetrapeptide-9, Synthetic Fluorphlogopite, Disteardimonium Hectorite, Dextrin, Pisum Sativum Extract, Tocopherol, Phenoxyethanol, CI 15985, CI 77891, Parfum

Niacinamide

Hexyldecanol

Paraffin

Polyacrylamide

Panthenol

Cetyl Alcohol

Butyrospermum Parkii Butter

Hydrogenated Polydecene

Tocopheryl Acetate

Palmitoyl Pentapeptide-4

Hydroxyacetophenone

Laureth-7

Cetearyl Alcohol

Cetearyl Glucoside

Behenyl Alcohol

Arachidyl Alcohol

Disodium EDTA

PEG-100 Stearate

Polysilicone-11

C13-14 Alkane

Benzyl Alcohol

Water, Niacinamide, Glycerin, Hexyldecanol, Dimethicone, Paraffin, Stearyl Alcohol, Polyacrylamide, Panthenol, Cetyl Alcohol, Butyrospermum Parkii Butter, Hydrogenated Polydecene, Tocopheryl Acetate, Palmitoyl Pentapeptide-4, Hydroxyacetophenone, Laureth-7, Cetearyl Alcohol, Cetearyl Glucoside, Behenyl Alcohol, Arachidyl Alcohol, Disodium EDTA, PEG-100 Stearate, Polysilicone-11, C13-14 Alkane, Phenoxyethanol, Benzyl Alcohol

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.

Emollients help soothe and hydrate the skin by trapping moisture.

Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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