tylotoin peptide

Product Information

• Product Name

  tylotoin peptide

• Documents
• Sequence Shortening

  H-KCVRQNNKRVCK-OH

• Sequence

  H-Lys-Cys-Val-Arg-Gln-Asn-Asn-Lys-Arg-Val-Cys-Lys-OH

• Length (aa)

  12

• Peptide Purity (HPLC)

  95.24%

• Molecular Formula

  C59H110N24O16S2

• Molecular Weight

  1475.78

• Source

  Synthetic

• Form

  Powder

• Description

  Tylotoin is a potential wound-healing-promoting peptide identified from salamander skin of Tylototriton verrucosus. Tylotoin directly enhances the motility and proliferation of keratinocytes, vascular endothelial cells, and fibroblasts, resulting in accelerated reepithelialization and granulation tissue formation in the wound site. Tylotoin also promotes the release of transforming growth factor β1 (TGF-β1) and interleukin 6 (IL-6), which are essential in the wound healing response.

• Storage Guidelines

  Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• References
  • Mu L, Tang J, Liu H, Shen C, Rong M, Zhang Z, Lai R. A potential wound-healing-promoting peptide from salamander skin. FASEB J. 2014 Sep;28(9):3919-29. doi: 10.1096/fj.13-248476. Epub 2014 May 27. PMID: 24868009; PMCID: PMC5395725.
• About TFA salt

  Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

  Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

  Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

  In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

• Molar Concentration Calculator

• Dilution Calculator

• Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.