Triptorelin Injection: Prostate Cancer Treatment

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This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

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Triptorelin is a medication that decreases testosterone to treat prostate cancer. This type of cancer develops in the prostate gland, a part of the male reproductive system. A healthcare provider will give you this injection in a hospital or clinic setting.

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TRIPTORELIN (TRIP toe REH lin) reduces the symptoms of prostate cancer. It works by decreasing levels of the hormone testosterone in the body. This prevents prostate cancer cells from spreading or growing.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Trelstar, Trelstar Depot, Trelstar Depot Plus Debioclip, Trelstar LA, Trelstar LA Plus Debioclip

They need to know if you have any of these conditions:

Diabetes (high blood sugar)
Heart disease
Irregular heartbeat or rhythm
Kidney disease
Trouble passing urine
An unusual or allergic reaction to triptorelin, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breast-feeding

This medication is injected into a muscle. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. It is not approved for use in children.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Do not take this medication with any of the following:

Cisapride
Dronedarone
Pimozide
Thioridazine

This medication may also interact with the following:

Certain medications for depression, anxiety, or other mental health conditions
Other medications that cause heart rhythm changes, such as dofetilide or ziprasidone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Your condition will be monitored carefully while you are receiving this medication. Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

You may need blood work while taking this medication.

This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy. Talk to your care team about reliable forms of contraception.

Side effects that you should report to your care team as soon as possible:

Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
Rapid or extreme change in emotion or mood
Rash, fever, and swollen lymph nodes
Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Seizures
Severe back pain, numbness or weakness of the hands, arms, legs, or feet, loss of coordination, loss of bowel or bladder control
Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
Trouble passing urine

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

Bone pain
Change in sex drive or performance
Headache
Hot flashes
Pain, redness, or irritation at injection site
Swelling of the ankles, hands, or feet

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.

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Triptorelin Injection: Prostate Cancer Treatment

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