Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

Tocobo Cotton Soft Sun Stick SPF50+ PA++++ Versus Mary & May Vegan Peptide Bakuchiol Sun Stick SPF 50+ PA++++

Tocobo Cotton Soft Sun Stick SPF50+ PA++++ Versus Mary & May Vegan Peptide Bakuchiol Sun Stick SPF 50+ PA++++ This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. What's inside Key Ingredients Benefits Concerns Ingredients Side-by-s

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Tocobo Cotton Soft Sun Stick SPF50+ PA++++ Versus Mary & May Vegan Peptide Bakuchiol Sun Stick SPF 50+ PA++++

This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Synthetic Wax

Dibutyl Adipate

Butylene Glycol Dicaprylate/Dicaprate

Octocrylene

Methyl Methacrylate Crosspolymer

Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

Ethylhexyl Methoxycinnamate

Dicaprylyl Carbonate

Cetyl Ethylhexanoate

Silica

Ethylhexyl Salicylate

Diethylamino Hydroxybenzoyl Hexyl Benzoate

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Tocopheryl Acetate

Ozokerite

Melia Azadirachta Leaf Extract

Melia Azadirachta Flower Extract

Coccinia Indica Fruit Extract

Solanum Melongena Fruit Extract

Aloe Barbadensis Flower Extract

Cardiospermum Halicacabum Flower/Leaf/Vine Extract

Curcuma Longa Root Extract

Corallina Officinalis Extract

Ocimum Sanctum Leaf Extract

Gossypium Herbaceum Extract

Sophora Flavescens Root Extract

Rheum Palmatum Root/Stalk Extract

Scutellaria Baicalensis Root Extract

Phellodendron Amurense Bark Extract

Oenothera Biennis Flower Extract

Ulmus Davidiana Root Extract

Pinus Palustris Leaf Extract

Pueraria Lobata Root Extract

Echium Plantagineum Seed Oil

Simmondsia Chinensis Seed Oil

Caprylyl Glycol

Bisabolol

Triethoxycaprylylsilane

Titanium Dioxide

Polyglyceryl-2 Triisostearate

Octyldodecanol

Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate

Helianthus Annuus Seed Oil Unsaponifiables

Tocopherol

Water

Butylene Glycol

1,2-Hexanediol

Parfum

Synthetic Wax, Dibutyl Adipate, Butylene Glycol Dicaprylate/Dicaprate, Octocrylene, Methyl Methacrylate Crosspolymer, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Ethylhexyl Methoxycinnamate, Dicaprylyl Carbonate, Cetyl Ethylhexanoate, Silica, Ethylhexyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Tocopheryl Acetate, Ozokerite, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Gossypium Herbaceum Extract, Sophora Flavescens Root Extract, Rheum Palmatum Root/Stalk Extract, Scutellaria Baicalensis Root Extract, Phellodendron Amurense Bark Extract, Oenothera Biennis Flower Extract, Ulmus Davidiana Root Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Echium Plantagineum Seed Oil, Simmondsia Chinensis Seed Oil, Caprylyl Glycol, Bisabolol, Triethoxycaprylylsilane, Titanium Dioxide, Polyglyceryl-2 Triisostearate, Octyldodecanol, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Helianthus Annuus Seed Oil Unsaponifiables, Tocopherol, Water, Butylene Glycol, 1,2-Hexanediol, Parfum

Isopropyl Palmitate

Butyloctyl Salicylate

Ethylhexyl Triazone

Polysilicone-15

Bakuchiol

Vinyldimethicone

Glyceryl Caprylate

Coco-Caprylate/Caprate

Ethylhexylglycerin

Polyhydroxystearic Acid

Aluminum Hydroxide

Polyglyceryl-10 Laurate

Acetyl Hexapeptide-8

Acetyl Octapeptide-3

Nonapeptide-1

Dipeptide-2

Dipeptide-4

Acetyl Tetrapeptide-2

Acetyl Tetrapeptide-3

Acetyl Tetrapeptide-5

Acetyl Tripeptide-1

Alanine/Histidine/Lysine Polypeptide Copper Hcl

Oligopeptide-6

Copper Tripeptide-1

Tripeptide-1

Tripeptide-2

Tripeptide-3

Pentapeptide-3

Hexapeptide-2

Hexapeptide-9

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Palmitoyl Dipeptide-7

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Pentapeptide-4

Palmitoyl Hexapeptide-12

Aroma

Ultramarines

Cetyl Ethylhexanoate, Methyl Methacrylate Crosspolymer, Butylene Glycol Dicaprylate/Dicaprate, Synthetic Wax, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Isopropyl Palmitate, Dicaprylyl Carbonate, Butyloctyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, Ozokerite, Polysilicone-15, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Bakuchiol, Vinyldimethicone, Titanium Dioxide, Glyceryl Caprylate, Caprylyl Glycol, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Coco-Caprylate/Caprate, Ethylhexylglycerin, Polyhydroxystearic Acid, Triethoxycaprylylsilane, Aluminum Hydroxide, Tocopherol, Butylene Glycol, Water, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Nonapeptide-1, Dipeptide-2, Dipeptide-4, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tripeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Oligopeptide-6, Copper Tripeptide-1, Tripeptide-1, Tripeptide-2, Tripeptide-3, Pentapeptide-3, Hexapeptide-2, Hexapeptide-9, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Dipeptide-7, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Aroma, Ultramarines

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

This ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.

It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.

Another pro?

It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.

That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.

Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).

On maximum concentrations:

In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This is a lightweight diester (caprylic/capric acid + butylene glycol) with emollient and skin conditioning properties.

According to a manufacturer, this ingredient can help add a "cushiony" oil phase without making it heavy.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Cetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.

Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.

Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.

As an emollient, Dicaprylyl Carbonate creates a film on the skin. This film traps moisture in, keeping your skin soft and hydrated.

Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).

DHHB is well-liked for:

DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.

This ingredient is soluble in oils, fats, and lipids.

This ingredient comes as a powder made up of small, porous, microbeads. It is used to add a silky feel to products and also helps absorb oil.

Ozokerite is a naturally occuring mineral wax. In cosmetics, ozokerite is used as a texture enhancer.

Ceresin wax is derived from this ingredient.

The melting point of ozokerite is 58-100 C.

Ozokerite is found all over the world including Scotland, the US, and India.

This ingredient is a water-in-oil emulsifier and is sometimes known by its trade name, Isolan GPS. It helps create stable emulsions by bridging oil and water phases without adding a greasy feel.

Common usage levels sit between 2-5% for this ingredient.

Synthetic Wax is a manufactured hydrocarbon wax. In formulas, it works as an occlusive emollient that helps reduce water loss and improves the spreadability of products.

Research comparing synthetic wax to traditional mineral-derived products found that formulas containing it perform as well for skin hydration.

It is considered non-comedogenic and vegan-friendly.

This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.

Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.

Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.

It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).

A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.

They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.

When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.

So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.

TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.

Together, they make a solid broad-spectrum system.

TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.

It's also unlikely to cause the "eye sting" some chemical filters are known for.

The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).

Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.

TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:

TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.

In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.

TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.

The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.

There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.

For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).

There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.

The science is still developing and it's a space worth watching rather than packing over.

However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Triethoxycaprylylsilane is a silicon-based surface modifier that makes sunscreens feel silky and makeup stay put.

Its main job is to coat mineral particles like titanium dioxide, zinc oxide, and color pigments in a thin, oily layer so they spread smoothly, don't clump, and stick to skin better.

This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).

This ingredient is used in makeup and skincare to thicken formulas, reduce shine, and give skin a silky-smooth feel.

It’s a white silicone powder that sits in fine lines and pores to blur their appearance though its effectiveness depends on the particle size.

You'll typically find this ingredient in amounts between 0.1-20%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →