Educational guide
The Ordinary Niacinamide 10% + Zinc 1% Versus La Roche-Posay Effaclar Duo[+] Unifiant
The Ordinary Niacinamide 10% + Zinc 1% Versus La Roche-Posay Effaclar Duo[+] Unifiant This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores. This acne moisturizer is formulated around Niacinamid
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
The Ordinary Niacinamide 10% + Zinc 1% Versus La Roche-Posay Effaclar Duo[+] Unifiant
This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores.
This acne moisturizer is formulated around Niacinamide and Salicylic Acid to clear breakouts and balance excess oil.
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Niacinamide 10%
Pentylene Glycol
Zinc PCA 1%
Dimethyl Isosorbide
Tamarindus Indica Seed Gum
Xanthan Gum
Isoceteth-20
Ethoxydiglycol
Phenoxyethanol
Chlorphenesin
Water, Niacinamide 10%, Pentylene Glycol, Zinc PCA 1%, Dimethyl Isosorbide, Tamarindus Indica Seed Gum, Xanthan Gum, Isoceteth-20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin
Glycerin
Dimethicone
Isocetyl Stearate
Niacinamide
Isopropyl Lauroyl Sarcosinate
Ammonium Polyacryloyldimethyl Taurate
Methyl Methacrylate Crosspolymer
T-Butyl Alcohol
Sodium Hydroxide
Oleic Acid
Salicylic Acid
Silica Silylate
Poloxamer 338
Nylon-12
Polysorbate 80
Zinc PCA
Linoleic Acid
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Isohexadecane
2-Oleamido-1,3-Octadecanediol
Octanediol
Capryloyl Salicylic Acid
Caprylyl Glycol
Piroctone Olamine
Myristyl Myristate
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Parfum
Sorbitan Oleate
Disodium EDTA
Potassium Cetyl Phosphate
BHT
Glyceryl Stearate Se
CI 77891
CI 77491
CI 77492
CI 77499
Mica
Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, T-Butyl Alcohol, Sodium Hydroxide, Oleic Acid, Salicylic Acid, Silica Silylate, Poloxamer 338, Nylon-12, Polysorbate 80, Zinc PCA, Linoleic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Isohexadecane, 2-Oleamido-1,3-Octadecanediol, Octanediol, Capryloyl Salicylic Acid, Caprylyl Glycol, Piroctone Olamine, Myristyl Myristate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Parfum, Sorbitan Oleate, Disodium EDTA, Potassium Cetyl Phosphate, BHT, Glyceryl Stearate Se, CI 77891, CI 77491, CI 77492, CI 77499, Mica
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Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Zinc PCA is a clever two-in-one molecule: the zinc salt of pyrrolidone carboxylic acid (PCA).
Think of it as two useful things bonded together; the PCA half is one of your skin's own natural moisturizing factors (NMF) so it helps hold water in the upper layers. On the other hand, the zinc half does the heavy lifting on oil and bacteria.
The zinc part slows down an enzyme that turns testosterone into DHT, the hormone that tells your oil glands to pump out more sebum. Less of that signal means less oil. It also gently fights acne-causing bacteria and soothes redness/irritation.
This is why Zinc PCA often shows up in products for oily, breakout-prone skin and greasy scalps.
One lab study also hinted it might have a small anti-aging perk because it seemed to protect collagen from UVA damage and even helped the skin make a bit more of it. That last bit is still early research done in a dish and not real skin, so take it as a nice bonus rather than a promise for now.
As for scar healing, the picture is more "maybe" than a firm yes. Zinc itself plays a real role in wound repair because it is a cofactor for the enzymes involved in collagen building, calming inflammation, and helping new skin cells cover a wound. Lower zinc levels are also linked to slower healing.
Most of the scar healing research is on zinc oxide or oral zinc rather than zinc PCA specifically, with a focus on healing fresh wounds instead of scars that are already there.
Direct evidence that zinc PCA improves the look of established scars is still limited at this time. Though it would be fair to say zinc PCA supports the general skin-repair environment thanks to its zinc content .
This ingredient is water-soluble and plays nicely with other actives like niacinamide and salicylic acid. It works best at mildly acidic formulas (~4-6 pH) and is effective at low levels. Around 0.1% is enough to be active and finished products commonly use it anywhere up to 4%.
Overall, this is a well-tolerated, low-drama multitasker that suits oily and acne-prone skin.