Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

The Ordinary Niacinamide 10% + Zinc 1% Versus Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator

The Ordinary Niacinamide 10% + Zinc 1% Versus Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores. This barrier-repair moisturizer is

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

The Ordinary Niacinamide 10% + Zinc 1% Versus Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator

This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Niacinamide 10%

Pentylene Glycol

Zinc PCA 1%

Dimethyl Isosorbide

Tamarindus Indica Seed Gum

Xanthan Gum

Isoceteth-20

Ethoxydiglycol

Phenoxyethanol

Chlorphenesin

Water, Niacinamide 10%, Pentylene Glycol, Zinc PCA 1%, Dimethyl Isosorbide, Tamarindus Indica Seed Gum, Xanthan Gum, Isoceteth-20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

Dimethicone

Butylene Glycol

Glycerin

Trisiloxane

Trehalose

Sucrose

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Hydroxyethyl Urea

Camellia Sinensis Leaf Extract

Silybum Marianum Extract

Betula Alba Bark Extract

Saccharomyces Lysate Extract

Aloe Barbadensis Leaf Water

Thermus Thermophillus Ferment

Caffeine

Sorbitol

Palmitoyl Hexapeptide-12

Sodium Hyaluronate

Caprylyl Glycol

Oleth-10

Sodium Polyaspartate

Saccharide Isomerate

Hydrogenated Lecithin

Tocopheryl Acetate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Glyceryl Polymethacrylate

Tromethamine

PEG-8

Hexylene Glycol

Magnesium Ascorbyl Phosphate

Disodium EDTA

BHT

CI 14700

CI 19140

Water, Dimethicone, Butylene Glycol, Glycerin, Trisiloxane, Trehalose, Sucrose, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyethyl Urea, Camellia Sinensis Leaf Extract, Silybum Marianum Extract, Betula Alba Bark Extract, Saccharomyces Lysate Extract, Aloe Barbadensis Leaf Water, Thermus Thermophillus Ferment, Caffeine, Sorbitol, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Caprylyl Glycol, Oleth-10, Sodium Polyaspartate, Saccharide Isomerate, Hydrogenated Lecithin, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Tromethamine, PEG-8, Hexylene Glycol, Magnesium Ascorbyl Phosphate, Disodium EDTA, BHT, Phenoxyethanol, CI 14700, CI 19140

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →