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The Ordinary Natural Moisturizing Factors + Beta Glucan Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

The Ordinary Natural Moisturizing Factors + Beta Glucan Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer This barrier-repair moisturizer is formulated around Beta-Glucan to strengthen the skin barrier and hydrate skin. This barrier-repair moistur

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

The Ordinary Natural Moisturizing Factors + Beta Glucan Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

This barrier-repair moisturizer is formulated around Beta-Glucan to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

PPG-24-Glycereth-24

Propanediol

Betaine

Beta-Glucan

Arginine

Glycine

Alanine

Serine

Proline

Threonine

Glutamic Acid

Lysine Hcl

Glucose

Maltose

Fructose

Trehalose

Xylitol

Anhydroxylitol

Xylitylglucoside

Sodium PCA

PCA

Sodium Lactate

Urea

Allantoin

Sodium Hyaluronate

Phospholipids

Sphingolipids

Glycerin

Pentylene Glycol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Sodium Hydroxide

Sodium Chloride

Sodium Citrate

Citric Acid

Tocopherol

P-Anisic Acid

Aminomethyl Propanol

Phenoxyethanol

Chlorphenesin

Water, PPG-24-Glycereth-24, Propanediol, Betaine, Beta-Glucan, Arginine, Glycine, Alanine, Serine, Proline, Threonine, Glutamic Acid, Lysine Hcl, Glucose, Maltose, Fructose, Trehalose, Xylitol, Anhydroxylitol, Xylitylglucoside, Sodium PCA, PCA, Sodium Lactate, Urea, Allantoin, Sodium Hyaluronate, Phospholipids, Sphingolipids, Glycerin, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Sodium Chloride, Sodium Citrate, Citric Acid, Tocopherol, P-Anisic Acid, Aminomethyl Propanol, Phenoxyethanol, Chlorphenesin

Dicaprylyl Carbonate

Hydrolyzed Sodium Hyaluronate

Aspartic Acid

Leucine

Lysine

Tyrosine

Phenylalanine

Valine

Isoleucine

Histidine

Ascorbic Acid

Saccharide Isomerate

Haematococcus Pluvialis Extract

Ceramide NP

Tocopheryl Acetate

Hexapeptide-11

Palmitoyl Tripeptide-1

Ananas Sativus Fruit Extract

Saccharomyces/Magnesium Ferment

Saccharomyces/Copper Ferment

Saccharomyces/Silicon Ferment

Butylene Glycol

Glyceryl Acrylate/Acrylic Acid Copolymer

Glyceryl Caprylate

Sucrose Stearate

Lecithin

Polyglyceryl-10 Laurate

Xanthan Gum

Cetearyl Olivate

Sorbitan Olivate

Carbomer

Cetearyl Alcohol

Lactobacillus Ferment

Leuconostoc/Radish Root Ferment Filtrate

Hydroxyacetophenone

CI 77491

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Pentylene Glycol, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Ascorbic Acid, Saccharide Isomerate, Haematococcus Pluvialis Extract, Ceramide NP, Tocopheryl Acetate, Tocopherol, Hexapeptide-11, Palmitoyl Tripeptide-1, Ananas Sativus Fruit Extract, Saccharomyces/Magnesium Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Silicon Ferment, Butylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Caprylate, Sucrose Stearate, Lecithin, Polyglyceryl-10 Laurate, Xanthan Gum, Cetearyl Olivate, Sorbitan Olivate, Sodium Citrate, Carbomer, Citric Acid, Cetearyl Alcohol, Sodium Hydroxide, Lactobacillus Ferment, Leuconostoc/Radish Root Ferment Filtrate, Hydroxyacetophenone, CI 77491

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.

It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.

Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.

Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.

Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.

Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Its main functions are to maintain the pH of a product and neutralize metal ions.

The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).

Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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