The Ordinary Matrixyl 10% + HA Versus Niod Multi-Molecular Hyaluronic Complex

The Ordinary Matrixyl 10% + HA Versus Niod Multi-Molecular Hyaluronic Complex

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

This hydrating serum is formulated around Sodium Hyaluronate Crosspolymer and Sodium Hyaluronate to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-38

Sodium Hyaluronate

Hydroxypropyl Cyclodextrin

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Polyacrylate Crosspolymer-6

Trisodium Ethylenediamine Disuccinate

Carbomer

Polysorbate 20

Ethoxydiglycol

Phenoxyethanol

Chlorphenesin

Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Polyacrylate Crosspolymer-6, Trisodium Ethylenediamine Disuccinate, Carbomer, Polysorbate 20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

Hydrolyzed Yeast Extract

Sodium Hyaluronate Crosspolymer

Dimethyl Isosorbide

Pentylene Glycol

Hydrolyzed Sodium Hyaluronate

Sodium Butyroyl Hyaluronate

Disodium Acetyl Glucosamine Phosphate

Betaine

Yeast Extract

Cetyl Hydroxyethylcellulose

Tamarindus Indica Seed Gum

Tremella Fuciformis Sporocarp Extract

Lecithin

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Myristoyl Nonapeptide-3

Magnesium Chloride

Sodium Benzoate

Potassium Sorbate

Ethylhexylglycerin

Polyglucuronic Acid

Water, Glycerin, Hydrolyzed Yeast Extract, Sodium Hyaluronate Crosspolymer, Dimethyl Isosorbide, Pentylene Glycol, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Butyroyl Hyaluronate, Polyacrylate Crosspolymer-6, Disodium Acetyl Glucosamine Phosphate, Betaine, Trisodium Ethylenediamine Disuccinate, Yeast Extract, Cetyl Hydroxyethylcellulose, Tamarindus Indica Seed Gum, Tremella Fuciformis Sporocarp Extract, Lecithin, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Myristoyl Nonapeptide-3, Magnesium Chloride, Sodium Benzoate, Potassium Sorbate, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Ethylhexylglycerin, Chlorphenesin, Phenoxyethanol, Polyglucuronic Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

PEG-40 Hydrogenated Castor Oil is an emulsifier derived from castor oil.

As an emulsifying agent, it helps other ingredients like fragrances and fat-soluble vitamins dissolve cohesively.

Due to its large molecule size, it doesn't penetrate beyond the skin's surface.

This ingredient has a solid regulatory track record; the CIR Expert Panel first concluded it was safe for use in cosmetics at concentrations up to 100% in 1997. A 2012 reassessment reaffirmed that finding. Safety studies have also found no irritation or evidence of toxicity.

A 2019 study did find this ingredient to grow Malassezia, so this ingredient may not be fungal acne safe.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

This ingredient is also known as Sepimax Zen.

We don't have a description for PPG-26-Buteth-26 yet.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Trisodium Ethylenediamine Disuccinate is used to help stabilize a product.

It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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