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The Ordinary "Buffet" Versus Vichy Liftactiv Peptide-C

The Ordinary "Buffet" Versus Vichy Liftactiv Peptide-C This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles. This anti-aging moisturizer is formulated around Adenosine and Ascorbyl Glucos

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

The Ordinary "Buffet" Versus Vichy Liftactiv Peptide-C

This anti-aging serum is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles.

This anti-aging moisturizer is formulated around Adenosine and Ascorbyl Glucoside to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Lactococcus Ferment Lysate

Acetyl Hexapeptide-8

Pentapeptide-18

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-38

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Acetylarginyltryptophyl Diphenylglycine

Sodium Hyaluronate Crosspolymer

Sodium Hyaluronate

Allantoin

Glycine

Alanine

Serine

Valine

Isoleucine

Proline

Threonine

Histidine

Phenylalanine

Arginine

Aspartic Acid

Trehalose

Fructose

Glucose

Maltose

Urea

Sodium PCA

PCA

Sodium Lactate

Citric Acid

Hydroxypropyl Cyclodextrin

Sodium Chloride

Sodium Hydroxide

Butylene Glycol

Pentylene Glycol

Acacia Senegal Gum

Xanthan Gum

Carbomer

Polysorbate 20

PPG-26-Buteth-26

PEG-40 Hydrogenated Castor Oil

Trisodium Ethylenediamine Disuccinate

Ethoxydiglycol

Sodium Benzoate

Caprylyl Glycol

Ethylhexylglycerin

Phenoxyethanol

Chlorphenesin

Water, Glycerin, Lactococcus Ferment Lysate, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium PCA, PCA, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Dimethicone

Isohexadecane

Alcohol Denat.

Silica

Hydroxyethylpiperazine Ethane Sulfonic Acid

Propanediol

Synthetic Wax

PEG-10 Dimethicone

Eperua Falcata Bark Extract

PEG-30 Dipolyhydroxystearate

Stearyl Alcohol

Sorbitan Oleate

Dimethicone/PEG-10/15 Crosspolymer

Dimethicone/Polyglycerin-3 Crosspolymer

Ceteareth-6

Sodium Acrylates Copolymer

Sodium Citrate

Sodium Phytate

Cyclodextrin

Adenosine

Ascorbyl Glucoside

Nylon-12

Isopropyl Alcohol

Propylene Carbonate

Dipropylene Glycol

Caprylic/Capric Triglyceride

Acetyl Tetrapeptide-9

Synthetic Fluorphlogopite

Disteardimonium Hectorite

Dextrin

Pisum Sativum Extract

Tocopherol

CI 15985

CI 77891

Parfum

Water, Glycerin, Dimethicone, Isohexadecane, Alcohol Denat., Silica, Hydroxyethylpiperazine Ethane Sulfonic Acid, Propanediol, Synthetic Wax, PEG-10 Dimethicone, Eperua Falcata Bark Extract, PEG-30 Dipolyhydroxystearate, Stearyl Alcohol, Sorbitan Oleate, Dimethicone/PEG-10/15 Crosspolymer, Dimethicone/Polyglycerin-3 Crosspolymer, Ceteareth-6, Sodium Acrylates Copolymer, Sodium Citrate, Sodium Hydroxide, Sodium Phytate, Cyclodextrin, Adenosine, Ascorbyl Glucoside, Nylon-12, Isopropyl Alcohol, Propylene Carbonate, Dipropylene Glycol, Caprylic/Capric Triglyceride, Caprylyl Glycol, Acetyl Tetrapeptide-9, Synthetic Fluorphlogopite, Disteardimonium Hectorite, Dextrin, Pisum Sativum Extract, Tocopherol, Phenoxyethanol, CI 15985, CI 77891, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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