Educational guide
The History of Whoo Bichup Self-Generating Anti-Aging Concentrate Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
The History of Whoo Bichup Self-Generating Anti-Aging Concentrate Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum This anti-aging serum is formulated around Panthenol and Panax Ginseng Root Extract to soften the look of wrin
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
The History of Whoo Bichup Self-Generating Anti-Aging Concentrate Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
This anti-aging serum is formulated around Panthenol and Panax Ginseng Root Extract to soften the look of wrinkles and strengthen the skin barrier.
This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Dipropylene Glycol
PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin
Glyceryl Polymethacrylate
Biosaccharide Gum-1
Dimethicone
1,2-Hexanediol
PEG-150
Methyl Trimethicone
Panthenol
Phenyl Trimethicone
Propylene Glycol
Cyclopentasiloxane
Polymethylsilsesquioxane
Hydrogenated Lecithin
Hydroxyproline
C14-22 Alcohols
Squalane
Panax Ginseng Root Extract
Ophiopogon Japonicus Root Extract
PEG-60 Hydrogenated Castor Oil
Butylene Glycol
Ceramide NP
Rehmannia Glutinosa Root Extract
Angelica Acutiloba Root Extract
Cornus Officinalis Fruit Extract
Nelumbo Nucifera Flower Extract
Nelumbo Nucifera Root Extract
Thymus Vulgaris Extract
Velvet Extract
Tromethamine
Macadamia Ternifolia Seed Oil
Triethylhexanoin
Carbomer
Dimethiconol
Dioscorea Japonica Root Extract
Glycyrrhiza Glabra Root Extract
PEG-10 Rapeseed Sterol
Arachidyl Glucoside
Butyrospermum Parkii Butter
Parfum
Algin
Sodium Polyacrylate
Typha Angustifolia Spike Extract
Cinnamomum Cassia Bark Extract
Paeonia Albiflora Root Extract
Glyceryl Stearate
Scutellaria Baicalensis Root Extract
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Atractylodes Japonica Rhizome Extract
Saposhnikovia Divaricata Root Extract
Zingiber Officinale Root Extract
Zizyphus Jujuba Fruit Extract
Stearic Acid
Angelica Gigas Root Extract
Cholesterol
PEG-100 Stearate
Beta-Glucan
Glycereth-20
Poria Cocos Extract
Theobroma Cacao Extract
Trisodium EDTA
Cordyceps Sinensis Extract
CI 15985
CI 19140
Arbutin
Glycosphingolipids
Oligopeptide-1
Oligopeptide-4
Phospholipids
Acetyl Hexapeptide-8
Copper Tripeptide-1
Hydrolyzed Soy Protein
Oligopeptide-2
Histidine Hcl
Arginine
Lysine
Valine
Threonine
Leucine
Methionine
Isoleucine
Phenylalanine
Tyrosine
Inositol
Cystine
Tryptophan
Folic Acid
Niacinamide
Pyridoxine Hcl
Thiamine Hcl
Calcium Pantothenate
Biotin
Riboflavin
Cyanocobalamin
Water, Glycerin, Dipropylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Glyceryl Polymethacrylate, Biosaccharide Gum-1, Dimethicone, 1,2-Hexanediol, PEG-150, Methyl Trimethicone, Panthenol, Phenyl Trimethicone, Propylene Glycol, Cyclopentasiloxane, Polymethylsilsesquioxane, Hydrogenated Lecithin, Hydroxyproline, C14-22 Alcohols, Squalane, Panax Ginseng Root Extract, Ophiopogon Japonicus Root Extract, PEG-60 Hydrogenated Castor Oil, Butylene Glycol, Ceramide NP, Rehmannia Glutinosa Root Extract, Angelica Acutiloba Root Extract, Cornus Officinalis Fruit Extract, Nelumbo Nucifera Flower Extract, Nelumbo Nucifera Root Extract, Thymus Vulgaris Extract, Velvet Extract, Tromethamine, Macadamia Ternifolia Seed Oil, Triethylhexanoin, Carbomer, Dimethiconol, Dioscorea Japonica Root Extract, Glycyrrhiza Glabra Root Extract, PEG-10 Rapeseed Sterol, Arachidyl Glucoside, Butyrospermum Parkii Butter, Parfum, Algin, Sodium Polyacrylate, Typha Angustifolia Spike Extract, Cinnamomum Cassia Bark Extract, Paeonia Albiflora Root Extract, Glyceryl Stearate, Scutellaria Baicalensis Root Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Atractylodes Japonica Rhizome Extract, Saposhnikovia Divaricata Root Extract, Zingiber Officinale Root Extract, Zizyphus Jujuba Fruit Extract, Stearic Acid, Angelica Gigas Root Extract, Cholesterol, PEG-100 Stearate, Beta-Glucan, Glycereth-20, Poria Cocos Extract, Theobroma Cacao Extract, Trisodium EDTA, Cordyceps Sinensis Extract, CI 15985, CI 19140, Arbutin, Glycosphingolipids, Oligopeptide-1, Oligopeptide-4, Phospholipids, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hydrolyzed Soy Protein, Oligopeptide-2, Histidine Hcl, Arginine, Lysine, Valine, Threonine, Leucine, Methionine, Isoleucine, Phenylalanine, Tyrosine, Inositol, Cystine, Tryptophan, Folic Acid, Niacinamide, Pyridoxine Hcl, Thiamine Hcl, Calcium Pantothenate, Biotin, Riboflavin, Cyanocobalamin
Bifida Ferment Lysate
PEG-8
Propanediol
Bis-PEG-18 Methyl Ether Dimethyl Silane
Methyl Gluceth-20
Glycereth-26
PEG-75
Adansonia Digitata Seed Extract
Tripeptide-32
Sodium Hyaluronate
Faex Extract
Lactobacillus Ferment
Cola Acuminata Seed Extract
Anthemis Nobilis Flower Extract
Hydrolyzed Algin
Pantethine
Caffeine
Lecithin
Sodium Rna
Bisabolol
Oleth-3 Phosphate
Caprylyl Glycol
Oleth-3
Oleth-5
Choleth-24
Jojoba Wax PEG-120 Esters
Ceteth-24
Tocopheryl Acetate
Triethanolamine
Tetrasodium EDTA
BHT
Xanthan Gum
Potassium Sorbate
Disodium EDTA
Phenoxyethanol
CI 14700
Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!