Sweet Chemistry – Sweet Chemistry, Inc.

2026 Best Biotech-Driven Skin Regeneration

"The best documentation for the science behind their products."

2026 Editor's Choice for Spring Beauty Staples

"This research-driven skincare brand erases signs of aging — and saves lives."

2026 Best Regenerative Serum

"Scientists revive damaged lungs for transplant."

2026 Best Barrier Repairing Serum

“Front and center in my product rotation”

2024 Best Breakthrough Technology Finalist

“Improves the structure, function, and appearance of skin.”

Winner Best Firming Serum 2024

“The best inflammaging skin care on the market right now.”

2023 Breakthrough Regenerative Medicine Ingredient

“Beauty has a new biotechnology-rooted player.”

2025 Brightest Start-Ups in Beauty

“Bone peptides might be the next retinol.”

2023 & 2024 Best Serum for Damaged Skin

3% Matrikynes® Peptides in Every Formula

Everyone’s skin has different needs, which is why all four of our products deliver similar benefits in different textures and finishes. Use individually, or layer from lightest to richest for amplified results. Clinically proven to increase skin barrier repair, function, and density in 4 weeks.

Water-Based Serum

Fortified Treatment Moisturizers

Oil-Based Serum

Water-Based Serum

Fortified Treatment Moisturizers

Oil-based Serum

Barrier Repairing Oil-Serum $170.00

Use alone as a treatment facial oil for dry skin, or infuse into creams for added repair and emollience, or as an overnight treatment.

Hyperpigmentation

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SCARS

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Inflammation

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TEXTURE

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Compromised Skin Barrier

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Hydration

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Every Few Decades, A New Innovation
Disrupts The Skincare Industry

89.3% agree their skin looks more resilient

"It seems to regenerate my skin."

85.7% saw reduced lines & wrinkles

"It improves all my fine lines and wrinkles."

91% saw improved skin texture

"My skin is smoother, brighter and firmer."

90% agree their skin looks healthier

"My skin feels healthy, hydrated and smoother"

89.3% saw smoother skin

"Makes my skin look younger - the fine lines disappear."

85.7% agree their skin looks revitalized

"Since using this, I haven't been wearing as much make-up."

• CURRENT PRACTICES

  Most cosmetic treatments that promise to “build collagen” (ablative lasers, radiofrequency microneedling, bio-stimulatory injectables, etc.) have the potential to damage your skin, and in the process, create collagen in the form of non-functioning scar tissue. 

  > According to a survey by The Aesthetic Society, plastic surgeons are reporting that many of these treatments can decrease skin quality/function over time and make it more difficult to perform future invasive procedures.

  SWEET CHEMISTRY PRODUCTS

  Our products repair your skin and visibly restore dermal collagen in as soon as 4 weeks without causing damage, forming healthy looking, living tissue.

  > This improves your skin quality as you age and allows you to stave off invasive procedures a little longer, should you desire them.

• Our polypeptides are not a marketing “complex”. They have been granted their own internationally recognized INCI name.

  CURRENT PRACTICES

  Artificial, chemically-synthesized peptides traditionally used in cosmetic formulas are singular solo performers and are thought to provide some regenerative benefits to your skin.

  SWEET CHEMISTRY PRODUCTS

  Sweet Chemistry formulas contain 3% Matrikynes® polypeptides derived from natural extracellular matrix.

  > These proprietary polypeptides consists of over 300 natural extracellular matrix polypeptides, are highly bioavailable, and clinically proven to improve skin barrier function, skin barrier repair, skin density, skin hydration, hyperpigmentation, and global fine lines and wrinkles.

  > Matrikynes® technology is also currently being used in some of the most advanced areas of biomedical research, specifically in clinical applications for organ tissue repair.

• We love telling the stories behind our formulas. Just not “ingredient stories”.

  CURRENT PRACTICES

  Many dermatological and botanical actives you will find in conventional cosmetic products are formulated at marketing levels, sometimes referred to as “ingredient stories”. 

  > This means your favorite product may only contain around 0.01% of any given active ingredient. This percentage is all it takes for an ingredient to appear in the ingredients list and be marketed to you as a “hero” ingredient. (The above percentage does not refer to milder prescription strength actives like retinoids)

  SWEET CHEMISTRY PRODUCTS

  We use a modern, transparent approach to formulating: All of our dermatological active ingredients are included at functional levels, with our botanical actives at a minimum of 1% each. In our ingredient list, we’re also always transparent about our 1% line. 

  > For our Elasticity Reinforcing Cream, this means we formulate using 30% less water with antioxidants and actives making up 45% of our emulsion. 

  > For our Reparative Oil Serum Infusion, it means you’re getting a waterless serum formulated with powerful actives and efficacious botanicals each at a minimum of 6%.

• Pesticides and preservatives are utilized to destroy living bacteria, not knowing the difference between good and bad flora. We limit your skin’s exposure to them.

  CURRENT PRACTICES

  Most traditional formulas use conventionally grown botanical ingredients that are exposed to some of the most potent pesticide residues and are preserved with the goal of maximizing long shelf-lives (average period-after-opening date: 12 months).

  > While preservatives are essential in extending shelf-life and ensuring the safety of water-based products, they are often used in excess.

  > Conventional pesticides have the potential to deplete your skin’s microbiome over time, harm farmers, soil, habitats, and other organisms, and also lead to the production of greenhouse gases.

  SWEET CHEMISTRY PRODUCTS

  Our botanical oils and extracts are not only certified organic and free from the most harmful pesticides but smartly protected and preserved without the need for excessive preservatives.

  > This gives you the convenience of shelf-life (6 month period-after-opening) without compromising your microbiome or putting soil, habitat, or farmer health, at risk.

• Our packaging uses 87% less plastic and protects our actives so you get the performance you expect. 

  TRADITIONAL PACKAGING

  Most airless bottles used for skincare are made from plastic. While the beauty industry is making an effort to use alternative materials such as glass, most glass used for beauty products tends to be heavier in weight than plastic packaging and therefore usually not the more eco-friendly choice.

  > At the same time, relying too much on plastic packaging is damaging to our environment, oceans, and habitats.

  SWEET CHEMISTRY PRODUCTS

  Meet the world’s first ultra-light glass airless bottle: Aside from the small plastic pump/overcap, our packaging is crafted from lightweight Italian glass, so light in fact, some of our customers have even mistaken it for plastic. 

  > Using 87% less plastic by mass than plastic airless bottles, our packaging helps us control our carbon emissions. They have also been shown to protect actives from oxidation more effectively than plastic or glass dropper bottles.

  > We also designed our bottle so you are able to dispense every last drop of product.

Improve skin barrier repair within 1 hour

Skin barrier repair improves 12% faster and 61% better within 1 hour, rapidly supporting skin’s restorative and refortifying abilities.

Increase skin density (collagen)

Skin density increases by 8.3% within 4 weeks, signaling skin to restore collagen and strengthen itself for a revitalized, youthful appearance.

Visibly reduces global fine lines & wrinkles

Fine lines and deep wrinkles are visibly reduced by 3.7% and skin looks noticeably smoother in only 4 weeks.

Increase skin hydration

Essential skin hydration increases significantly by 8.4% within 4 weeks and continues to build with regular use. 

Improve skin barrier function

Skin barrier function improves dramatically by 5.8% in just 4 weeks, enabling skin to ‘act efficiently’ like younger, healthy skin.

Improve the appearance of hyperpigmentation & age spots

Hyperpigmentation/age spots are reduced by 3.6% within 4 weeks for more even skin tone and brighter complexion.

Cause no irritation and minimal sensitization

Occlusive repeated insult patch test was performed with Matrikynes® (neat), and no irritation or sensitization to was observed.

Visibly reduce redness

Redness is significantly reduced and skin tone as well as texture are improved.

10/10 would recommend! It's worth every penny! Love that it's cruelty-free, fragrance-free, and packed with antioxidants. My combination skin is finally balanced and glowing! It's reduced my pores, evened out my tone, and given me a radiant complexion. A game-changer for anyone seeking effective, sustainable skincare.

Verified customer

Missali

If your skin craves moisture like mine does this product is definitely worth giving a shot. The Elasticity Reinforcing Cream is a lightweight moisturizer that seeps into your skin giving it much needed regeneration and hydration without leaving a greasy residue which is perfect for wearing underneath your makeup. 

Verified customer

Rebekahh

Every time I use this product, I am amazed at how effective it is in making my skin look so healthy and supple. The product definitely gives my complexion a youthful bounce.

Verified customer

Chaeyoungy

Sweet Chemistry Reparative Oil combined with Elasticity Reinforcing Cream has returned my skin to a more youthful appearance! Friends say I look glowing and I’m turning 65 this year!

Verified customer

Marguerite C.

Let me tell you, it did not disappoint. My skin looks and feels hydrated and bouncy. A big win in my book.

Verified customer

Wendy C.

“Without ECM, Life Could Not Exist.
Plants Would Not Grow Tall, and Animals
Could neither Swim, nor Walk, nor Fly.”

 - WH LEWIS, LIFE SCIENCES AND CELL BIOLOGY, 1922

free returns

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free shipping

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Conscientious sourcing

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reduced environmental impact

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Cruelty free

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iResearch

The iResearch Institute is a study program for high school students without access to advanced science education - founded by the godmother of science research, Dr. Serena McCalla.

YoungArts

YoungArts identifies exceptional young artists, amplifies their potential, and invests in their lifelong creative freedom. It envisions a world that embraces artists as vital to our humanity.

Xylyx Bio

Our parent company, Xylyx Bio, is a biomedical technology leader in tissue engineering and organ rehabilitation, dedicated to eliminating the organ donor waitlist.

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