Educational guide
Skinfood Acorn Pore Peptide Pad Versus AMPLE:N Peptide Shot Ampoule
Skinfood Acorn Pore Peptide Pad Versus AMPLE:N Peptide Shot Ampoule This pore-care toner pad uses a pre-saturated pad with Niacinamide and Gluconolactone to refine the look of pores and refine skin texture. This anti-aging ampoule is formulated around Niacinam
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Skinfood Acorn Pore Peptide Pad Versus AMPLE:N Peptide Shot Ampoule
This pore-care toner pad uses a pre-saturated pad with Niacinamide and Gluconolactone to refine the look of pores and refine skin texture.
This anti-aging ampoule is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Quercus Acutissima Fruit Extract 10%
Propanediol
Butylene Glycol
Glycerin
Niacinamide
Alcohol
Gluconolactone
Sodium Citrate
Tromethamine
Hydroxyacetophenone
PPG-13-Decyltetradeceth-24
1,2-Hexanediol
Hamamelis Virginiana Extract
Allantoin
Opuntia Ficus-Indica Stem Extract
Adenosine
Polyglyceryl-10 Laurate
Diospyros Kaki Fruit Extract
Camellia Sinensis Leaf Extract
Castanea Crenata Shell Extract
Sodium Hyaluronate
Citric Acid
Hydroxyethylcellulose
Enantia Chlorantha Bark Extract
Sodium Phytate
Dextrin
Beta-Glucan
Theobroma Cacao Extract
Eucalyptus Globulus Leaf Oil
Rosmarinus Officinalis Leaf Oil
Amyris Balsamifera Bark Oil
Caprylyl Glycol
Hydrolyzed Lupine Protein
Salvia Officinalis Oil
Glyceryl Acrylate/Acrylic Acid Copolymer
Citrus Aurantium Bergamia Fruit Oil
Pueraria Lobata Root Extract
Ulmus Davidiana Root Extract
Oenothera Biennis Flower/Leaf/Stem Extract
Pinus Palustris Leaf Extract
Helianthus Annuus Seed Oil
Salvia Sclarea Oil
Palmitoyl Tripeptide-5
Oleanolic Acid
Water, Quercus Acutissima Fruit Extract 10%, Propanediol, Butylene Glycol, Glycerin, Niacinamide, Alcohol, Gluconolactone, Sodium Citrate, Tromethamine, Hydroxyacetophenone, PPG-13-Decyltetradeceth-24, 1,2-Hexanediol, Hamamelis Virginiana Extract, Allantoin, Opuntia Ficus-Indica Stem Extract, Adenosine, Polyglyceryl-10 Laurate, Diospyros Kaki Fruit Extract, Camellia Sinensis Leaf Extract, Castanea Crenata Shell Extract, Sodium Hyaluronate, Citric Acid, Hydroxyethylcellulose, Enantia Chlorantha Bark Extract, Sodium Phytate, Dextrin, Beta-Glucan, Theobroma Cacao Extract, Eucalyptus Globulus Leaf Oil, Rosmarinus Officinalis Leaf Oil, Amyris Balsamifera Bark Oil, Caprylyl Glycol, Hydrolyzed Lupine Protein, Salvia Officinalis Oil, Glyceryl Acrylate/Acrylic Acid Copolymer, Citrus Aurantium Bergamia Fruit Oil, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract, Oenothera Biennis Flower/Leaf/Stem Extract, Pinus Palustris Leaf Extract, Helianthus Annuus Seed Oil, Salvia Sclarea Oil, Palmitoyl Tripeptide-5, Oleanolic Acid
Dipropylene Glycol
PEG-32
Biosaccharide Gum-1
Trehalose
Acetyl Hexapeptide-8
Arginine
Panthenol
Hydrogenated Lecithin
Dipotassium Glycyrrhizate
Helichrysum Arenarium Extract
Yeast Extract
Palmitoyl Pentapeptide-4
Pearl Extract
Dimethicone
PEG-60 Hydrogenated Castor Oil
Carbomer
Xanthan Gum
Titanium Dioxide
Sodium Palmitoyl Sarcosinate
Mica
Caramel
Agar
Calcium Alginate
Gellan Gum
Polysorbate 20
Propylene Glycol
Glyceryl Caprylate
Phenylpropanol
Palmitoyl Oligopeptide
Lactic Acid
Polyvinyl Alcohol
Glycolic Acid
Phenoxyethanol
Parfum
Ethylhexylglycerin
Tetrasodium EDTA
Water, Glycerin, Butylene Glycol, Dipropylene Glycol, Alcohol, PEG-32, Biosaccharide Gum-1, Niacinamide, Trehalose, Adenosine, Acetyl Hexapeptide-8, Arginine, Panthenol, Hydrogenated Lecithin, Beta-Glucan, Dipotassium Glycyrrhizate, Helichrysum Arenarium Extract, Yeast Extract, Palmitoyl Pentapeptide-4, Pearl Extract, Dimethicone, PEG-60 Hydrogenated Castor Oil, 1,2-Hexanediol, Carbomer, Xanthan Gum, Titanium Dioxide, Sodium Palmitoyl Sarcosinate, Glyceryl Acrylate/Acrylic Acid Copolymer, Mica, Caramel, Agar, Calcium Alginate, Gellan Gum, Polysorbate 20, Propylene Glycol, Caprylyl Glycol, Glyceryl Caprylate, Phenylpropanol, Palmitoyl Oligopeptide, Lactic Acid, Polyvinyl Alcohol, Glycolic Acid, Phenoxyethanol, Parfum, Ethylhexylglycerin, Tetrasodium EDTA
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.
This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.
Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!