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Sidmool Honey Peptide Mist Versus Sidmool Galatokside Real N.M.F Barrier Serum

Sidmool Honey Peptide Mist Versus Sidmool Galatokside Real N.M.F Barrier Serum This hydrating treatment is formulated around Honey Extract and Propolis Extract to hydrate skin and calm redness. This barrier-repair serum is formulated around Galactomyces Fermen

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Sidmool Honey Peptide Mist Versus Sidmool Galatokside Real N.M.F Barrier Serum

This hydrating treatment is formulated around Honey Extract and Propolis Extract to hydrate skin and calm redness.

This barrier-repair serum is formulated around Galactomyces Ferment Filtrate and Sodium PCA to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Honey Extract

Water

Opuntia Ficus-Indica Stem Extract

Glycerin

Hyaluronic Acid

Sorbitol

Propolis Extract

Royal Jelly Extract

Oligopeptide-1

Sh-Polypeptide-11

Sh-Oligopeptide-2

Beta-Glucan

Panthenol

Hydrolyzed Collagen

Portulaca Oleracea Extract

Tripeptide-1

Anthemis Nobilis Flower Extract

Butylene Glycol

Trehalose

Dipotassium Glycyrrhizate

Allantoin

Scutellaria Baicalensis Root Extract

Paeonia Suffruticosa Root Extract

1,2-Hexanediol

Caprylyl Glycol

Honey Extract, Water, Opuntia Ficus-Indica Stem Extract, Glycerin, Hyaluronic Acid, Sorbitol, Propolis Extract, Royal Jelly Extract, Oligopeptide-1, Sh-Polypeptide-11, Sh-Oligopeptide-2, Beta-Glucan, Panthenol, Hydrolyzed Collagen, Portulaca Oleracea Extract, Tripeptide-1, Anthemis Nobilis Flower Extract, Butylene Glycol, Trehalose, Dipotassium Glycyrrhizate, Allantoin, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, 1,2-Hexanediol, Caprylyl Glycol

Galactomyces Ferment Filtrate 71%

Sodium PCA

Sodium Lactate

Urea

Pentylene Glycol

Glycosaminoglycans

Polyglutamic Acid

Sodium Hyaluronate

Rh-Polypeptide-11

Madecassoside

Madecassic Acid

Asiaticoside

Asiatic Acid

Rosa Damascena Callus Culture Extract

Adenosine

Heptyl Glucoside

Galactomyces Ferment Filtrate 71%, Sodium PCA, Sodium Lactate, Urea, Pentylene Glycol, Glycosaminoglycans, Glycerin, Butylene Glycol, Polyglutamic Acid, Hyaluronic Acid, Sodium Hyaluronate, Oligopeptide-1, Rh-Polypeptide-11, Sh-Oligopeptide-2, Madecassoside, Madecassic Acid, Asiaticoside, Asiatic Acid, Rosa Damascena Callus Culture Extract, Allantoin, Adenosine, Dipotassium Glycyrrhizate, 1,2-Hexanediol, Heptyl Glucoside

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Oligopeptide-1 is another name for Epidermal Growth Factor (EGF). In a formula, EGF works as a signaling ingredient.

EGF binds to receptors on your skin cells and tells keratinocytes/fibroblasts to divide, move, and rebuild the skin's support structure.

A 2012 open-label study on a barley-derived EGF serum reported statistically significant improvements in fine-lines, skin texture, pore size, and uneven skin tone, with changes showing up within the first month of 2x/daily use.

And a 2023 review found generally positive but modest results for growth factor products while pointing out that most trials are small, often industry-funded, and rarely test EGF on its own.

So, a fair summary of this ingredient would be "promising with real mechanistic backing, but not yet large-scale proof".

Concentration-wise, EGF is biologically active at very tiny amounts so finished products use it at low levels (think parts per million).

Raw material supplies usually sell a pre-diluted EGF solution and recommend adding roughly 1-5% of that solution to a formula.

Another practical catch: EGF is a fragile protein so it reacts badly to heat and the wrong pH. This just means it relies heavily on good packaging and a solid delivery system to stay active in a bottle.

Oligopeptide-1 and Sh-Oligopeptide-1. The "sh-" prefix just means "synthetic human" and it tells you that it's the lab grown version.

This peptide has similar properties to Sh-Oligopeptide-1.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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