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Psychedelics, peptides and GLP-1s | Fierce Pharma

Is biotech taking a trip to the world of psychedelic drugs? Why is Novo Nordisk going after Eli Lilly’s Zepbound ads? And what are peptides? This week on "The Top Line," Fierce's Zoey Becker, Will Maddox and Kevin Dunleavy chat about some of the biggest recent

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This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Is biotech taking a trip to the world of psychedelic drugs? Why is Novo Nordisk going after Eli Lilly’s Zepbound ads? And what are peptides?

This week on "The Top Line," Fierce's Zoey Becker, Will Maddox and Kevin Dunleavy chat about some of the biggest recent stories. From a psychedelics acquisition that could spark more movement in the emerging field to an advisory committee meeting on peptides shrouded in political controversy to a lawsuit between the two major obesity drugmakers, we’ll catch you up on the latest developments shaking up the biopharma world.

To learn more about the topics in this episode:

  • ‘A rising tide scenario’: Why other Big Pharmas could follow Lilly into psychedelics
  • UPDATE: Peptides favored on 1st day of closely watched FDA compounding adcomm
  • Peptide adcomm Day 2: Emideltide voted down in panel's 1st pushback
  • Novo Nordisk files lawsuit accusing rival Eli Lilly of running ‘false and misleading’ GLP-1 ads
  • Novo escalates Lilly false advertising suit with planned bid to halt comparative ads

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Related questions

01Is Lenomorelin Worth It? Here’s the Truth!

In my opinion? Absolutely, yes! Lenomorelin, also known as ghrelin, is a natural hormone with extensive pharmacodynamic research backing its legitimacy. The real question is: what’s your goal? For Weight Gain : Lenomorelin is an excellent choice. It’s effective for increasing body weight naturally and safely. For Bodybuilders or Athletes : Consider alternatives. Growth hormone secretagogue (GHS) peptides deliver faster, more versatile results compared to Lenomorelin. These GHS peptides mimic ghrelin but outperform it in terms of efficiency and efficacy. They’re better suited for muscle growth and performance enhancement. To sum up: Lenomorelin is great for weight gain, but other peptides may be better for athletic performance. Choose wisely!

Source: muscleandbrawn.com ↗
02How Does Follistatin Work

Follistatin 344 follows multiple courses of action to trigger specific changes in the body. Myostatin ( 1 ), a growth and differentiation factor protein, is produced by myocytes (muscle cells). The primary function of myostatin is to act as a regulator by limiting the growth of muscles so that they don’t grow out of shape. Follistatin 344 acts as a myostatin inhibitor. This subsequent blocking of myostatin by follistatin 344 leads to the suppression of myostatin activity ( 2 ). Thus, myostatin can’t act as a potent negative regulator of muscle growth. Activin proteins enhance the secretion of follicle-stimulating hormone (FSH). However, in men, higher levels of follicle-stimulating hormone (FSH) limit muscle growth and cause abnormal testicle functioning. Follistatin 344 inhibits the activin, which results in decreased secretion of the hormone. Follistatin 344 acts on the granulosa cells to trigger the release of progesterone ( 3 ). As progesterone is one of the main hormones regulating the menstrual cycle, slight fluctuations in the hormonal levels can disturb the whole cycle. Although no human trials have confirmed these results, animal-based studies suggest that follistatin can reduce the life and growth of cancer cells and minimize the chances of metastasis ( 4 ).

Source: muscleandbrawn.com ↗
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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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