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PepTrack™ Peptide Libraries

PepTrack™ Peptide Libraries Antigen-specific stimulation in T-cell assays Immune monitoring T-cell epitope identification T-cell epitope mapping Development of cellular therapy and immunotherapy approaches Vaccine development Fast Track T-cell epitope discover

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

PepTrack™ Peptide Libraries

Antigen-specific stimulation in T-cell assays

Immune monitoring

T-cell epitope identification

T-cell epitope mapping

Development of cellular therapy and immunotherapy approaches

Vaccine development

Fast Track

T-cell epitope discovery, Antigen target identification, Pathogen-spanning T-cell epitope discovery

Unpurified

Statistical LC-MS (5% of all peptides)

10-50µg of target peptide

Fast Track PLUS

Neo-epitope prioritization, Target identification, Biological screening

LC-MS and quantitation of each peptide

Research Track

T-cell epitope discovery, Immunogenicity testing, Identification of immunodominant antigens

Unpurified (each peptide detectable by LC-MS or MALDI-MS)

LC-MS / Maldi-MS for each peptide

1-4mg or 5-10mg

Research Track PLUS

T-cell epitope discovery, Target identification, Biological screening with each peptide analyzed by LC-MS

Unpurified (Major product component is guaranteed to be peptide of interest)

LC-MS for each peptide

Development Track

Immune monitoring, T-cell epitope mapping

>70%

Trial Track

Clinical immune monitoring, Development of immunotherapy

>80% >90% >95%

Applications: T-cell epitope discovery, target identification, biological screening

Purity: Unpurified

QC /QA: Statistical LC-MS of 5% of the peptides

Peptide Length: 6-15 aa (for longer peptides, please inquire)

Amount per Peptide: 10-50µg of target peptide (larger amount upon request)

Delivery Format: Freeze-dried in 96 well plates

Delivery Time: 2 weeks minimum

Minimum Order: 24 peptides

QC /QA PLUS: LC-MS and quantitation of each peptide included

Delivery Time: 3 weeks minimum

Applications: T-cell epitope discovery, target identification, biological screening with each peptide analyzed by LC-MS

Purity: Unpurified (each peptide must be detectable by LC-MS or MALDI-MS)

Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides.

QC /QA: LC-MS / Maldi-MS for each peptide

Peptide Length: 15 aa

Amount per Peptide: 1-4mg or 5-10mg

Delivery Format: Freeze-dried in 96 tube racks

Delivery Time: 2-4 weeks

Purity PLUS: Major product component according to LC-MS analysis is guaranteed to be peptide of interest

QC /QA: LC-MS for each peptide

Delivery Time: 2-4 weeks (depending on number of peptides)

Applications: Antigen-specific stimulation of T-cells for immune monitoring and other applications that require defined peptide purity

Purity: > 70% guaranteed for each peptide

Delivery Time: 4-5 weeks

Applications: Antigen-specific stimulation of T-cells for immune monitoring or immunotherapy in clinical trials

Quality: For even higher quality, please check our Clinical Peptides & Pools!

Purity: > 80%, 90%, 95% or 97% guaranteed for each peptide

Applications

Applications for PepTrack™ Peptide Libraries

Immune monitoring profiling by ELISpot

T-cell epitope discovery, mapping & validation

Peptide vaccine & development

Optimization and validation of T-cell assays

Translation of NGS results into neo epitope libraries

Vaccine efficacy testing

Immunotherapy

Biological screening

Benefits

Benefits of PepTrack™ Peptide Libraries

Flexible peptide libraries tailored for cellular assays

Best pricing in industry!

Custom Peptide Synthesis avoiding toxic inhibition or de novo epitopes

Aliquotation, pooling and advanced QC (UPLC, AAA, residual solvent determination, stability testing, etc.)

Post-Translational Modifications (PTMs) available

Proven track record for applications in clinical studies

Testimonials

Testimonials for PepTrack™ Peptide Libraries

References

References for PepTrack™ Peptide Libraries

Related Products

Related Products

Custom Peptide Synthesis

Custom PepMix™ Peptide Pools

Peptide Modifications & Speciality Peptides

Comprehensive Solutions for Post-Translational Modifications (PTMs)

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

Research context

Read sources and limitations before applying a claim.

Autoimmune disease mechanism studies

Determining the events that lead to autoimmunity requires reagents to specifically detect the autoimmune rather than the normal physiological interactions, an ideal tool to address this is peptide libraries. Peptide libraries containing all human autoantigens, such as myelin basic protein, insulin or joint-specific collagens, are synthesized in all possible posttranslationally modified forms known to be present in the disease state, including citrullination, deamidation, and oxidation. Human T-cell clones from the periphery of patients and controls are then screened with these libraries in either tolerogenic or proinflammatory cytokine environments in order to identify which modified peptides contain cryptic epitopes that escaped central deletion and lead to tissue-specific inflammation. Alanine-scanning and position-substitution variants are used to more precisely determine the minimal amino acid motifs necessary for the peptide to become an encephalitogenic or arthritogenic peptide. In addition to mechanistic study, the peptide libraries are used to discover the tolerogenic peptides themselves; through structure–activity relationships, analogues that can anergize autoreactive T cells or induce antigen-specific regulatory T cells can be identified.

Source: creative-peptides.com ↗

Supporting Clinical Trials! - Trial Grade Peptide Libraries

Published on 17/04/2026 The transition from discovery research to clinical development is one of the most critical phases in medicinal research. Data generated in early screening and target discovery must now be translated into robust, reproducible, and regulatory-compliant tools suitable for clinical studies. This requires peptide libraries to be produced under stringent production conditions. JPT’s Trial Grade and Premium Grade peptide libraries support: Immune monitoring and response profiling Biomarker validation Patient stratification Assay standardization across trial sites In this final newsletter, we highlight how JPT supports clinical research through Trial Grade and Premium Grade peptides. Trial Track Peptide Libraries As the name implies, PepTrack Trial Track is tailored to support peptide-based applications in clinical trials, ensuring that peptides used in clinical assays meet the quality and reproducibility requirements needed for reliable clinical data generation. Applications: Antigen-specific stimulation of T-cells for immune monitoring or immunotherapy in clinical trials Quality: For even higher quality, please check out our Clinical Peptides & Pools! Purity: > 80%, 90%, 95% or 97% guaranteed for each peptide Capping: Truncated peptides are capped after each synthesis step. This eliminates the major source of false positive T-cell responses, deletion peptides. QC /QA: LC-MS for each peptide Peptide Length: 15 aa Amount per Peptide: 1-4mg or 5-10mg Delivery Format: Freeze-dried in 96 tube racks Delivery Time: 4-5 weeks Minimum Order: 24 peptides But wait, there is more! Premium Grade PepMix™ – Bridging Research and Clinical Use Did you know we also offer Premium Grade peptide control pools? At the interface between discovery and clinical research, Premium Grade PepMix™ provides a highly standardized solution for immune monitoring and translational studies. Compared to regular control pools, Premium Grade PepMix™ offers: High purity (>90%) and consistency (validated pooling methods) Optimized performance in immunological assays Recurrent Performance testing Cytotox, endoxin, steriliy testing Updated CoA 637,50after each test Controlled synthesis processes Additional capping step to each peptide synthesis step to prevent de novo epitope formation High batch-to-batch consistency Comprehensive analytical documentation Customized plate and vial formats Support for longitudinal and multi-center studies

Source: jpt.com ↗
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Peptide Therapy Guide Editorial Team

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