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Peptides and weight reduction: a scientific perspective

Peptides and weight reduction: a scientific perspective When we eat carbs/sugars: Your blood sugar level increases The pancreas senses the rise in blood sugar and releases insulin This insulin triggers the transport of glucose into cells, especially muscle and

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Peptides and weight reduction: a scientific perspective

When we eat carbs/sugars:

Your blood sugar level increases

The pancreas senses the rise in blood sugar and releases insulin

This insulin triggers the transport of glucose into cells, especially muscle and liver cells

We have small sugar stores, so any excess is easily converted to fat, mainly by the liver, and then transported to the fat cells for storage

The body prefers to use fat as fuel for activity. However, with constantly full sugar stores, it tends to use this before using the stored fat. On a relative carbohydrate dominant diet, where the sugar stores are regularly refilled and overfilled, we store fat easily but have trouble burning the fat stores.

What happens when we add Peptides?

Some peptides stimulate your pituitary gland to naturally release more Human Growth Hormone (HGH), while another consists of the end of the HGH molecule. These peptides have been found to inhibit glucose burning and promote fat burning.

As a result, your body burns fat for energy immediately! Normally, a person’s body will seek to use their glucose energy reserves before seeking energy from fat reserves. By using peptides, your body is forced to seek energy from your fat reserves immediately, resulting in fat loss!

Peptides have the potential to inhibit glucose and fat storage in our fat cells and promotes fat promote therefore we burn fat performing everyday tasks… even while sleeping. It is important to remember that if you are already seeing an increase in unhealthy belly fat (visceral fat) you must make the necessary modifications to your diet and lifestyle sooner than later. Belly fat is oftentimes a precursor to chronic disease.

Declining GH levels are associated with increased visceral fat storage

There is substantial evidence that the (GH)/insulin-like growth factor (IGF) system has involvement in the development of obesity. Both GH and IGF-I have direct effects on the proliferation and differentiation of fat cells. This hormonal system is involved in the cross-talk between fat tissue, liver, and the pituitary gland.

Researchers indicate that there is a rationale for targeting this system in the treatment of visceral obesity when it is associated with growth hormone deficiency or metabolic syndrome. Studies involving men and women with abdominal adiposity, (even in women who are menopausal or postmenopausal) reveal a significant reduction in visceral fat through GH stimulation and supplementation.

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References / Links

Møller, N., Jørgensen, J. O. (2009). Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocrine Reviews, 30(2), 152–177. PubMed

Berryman, D. E., Glad, C. A., List, E. O., Johannsson, G. (2013). The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations. Nature Reviews Endocrinology, 9(6), 346–356. PubMed

Rudman, D., Feller, A. G., Nagraj, H. S., et al. (1990). Effects of human growth hormone in men over 60 years old. New England Journal of Medicine, 323(1), 1–6. PubMed

Johannsson, G., Marin, P., Lönn, L., et al. (1997). Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism. Journal of Clinical Endocrinology & Metabolism, 82(3), 727–734. PubMed

Richelsen, B., Pedersen, S. B., Borglum, J. D., Moller-Pedersen, T., Jorgensen, J., Christiansen, J. S. (1994). Growth hormone treatment of obese women for 5 wk: effect on body composition and adipose tissue LPL activity. American Journal of Physiology, 266(6 Pt 1), E211–E216. PubMed

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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