Educational guide
Peptide Linkers | Peptides | MedChemExpress
Peptide Linkers Peptide Linkers (26) 1 2 Formula: C196H290BrN55O69.xC2HF3O2 Molecular Weight: 4600.70 (free base) AMG133 peptide payload TFA is a GLP-1 analog agonist peptide. AMG133 peptide payload TFA potently activates GLP-1R and exhibits weight loss and me
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Peptide Linkers
Peptide Linkers (26)
1
2
Formula: C196H290BrN55O69.xC2HF3O2
Molecular Weight: 4600.70 (free base)
AMG133 peptide payload TFA is a GLP-1 analog agonist peptide. AMG133 peptide payload TFA potently activates GLP-1R and exhibits weight loss and metabolic improvement activities. AMG133 peptide payload TFA can be used for the synthesis of AMG 133 (HY-164535).
August 31
Formula: C20H28N4O7
Molecular Weight: 436.46
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
Formula: C38H64N12O14
Molecular Weight: 912.99
Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide.
Formula: C30H30N4O7
Molecular Weight: 558.58
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.
Formula: C32H38N6O8
Molecular Weight: 634.68
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
Formula: C24H42N6O7
Molecular Weight: 526.63
PLGLAG is a peptide that serves as the linker in activatable cell-penetrating peptides (ACPPs) and can be used in cancer research.
Formula: C32H54N10O12
Molecular Weight: 770.83
Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate.
Formula: C8H14N4O5
Molecular Weight: 246.22
Tetraglycine is a oligopeptide composed of four glycine monomers.
Formula: C31H54N6O11
Molecular Weight: 686.79
Ac-EEVC-OH is a ADC Linker that can be used for the synthesis of ADC molecules.
Formula: C42H81N17O10
Molecular Weight: 984.20
PRRVRLK acetate is a peptide linker. PRRVRLK acetate can be used to make fusion protein.
Formula: C23H21N3O7
Molecular Weight: 451.43
Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker.
Formula: C15H20N4O5
Molecular Weight: 336.34
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689).
Formula: C60H68F3N11O36S
Molecular Weight: 1608.29
Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
Formula: C58H67N11O34S
Molecular Weight: 1494.27
Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.
Formula: C34H39F3N6O10
Molecular Weight: 748.70
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
Formula: C22H36N10O13
Molecular Weight: 648.58
GGGGSGGGGS is a chimeric peptide composed of four peptides. GGGGSGGGGS can efficiently bind to small intestinal submucosa (SIS) membranes. GGGGSGGGGS can be used for research on infectious or inflammatory conditions.
Formula: C38H66N6O13
Molecular Weight: 814.96
Boc-PEG6-Val-Cit-PAB-OH is an ADC linker that can be used for synthesizing antibody-drug conjugates (ADC). Boc-PEG6-Val-Cit-PAB-OH can be used for cancer research.
Formula: C50H84N16O18
Molecular Weight: 1197.30
Ac-pSar16-OH is a polysarcosine which can replace PEG for therapeutic protein conjugation.
Formula: C100H132N26O25.xC2HF3O2
Molecular Weight: 2212.30 (free acid)
2× ST-tag II TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II TFA specifically binds to ST Tactin. 2× ST-tag II TFA can be used to construct DNA-protein hybrids.
Formula: C100H132N26O25
Molecular Weight: 2098.28
2× ST-tag II is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II specifically binds to ST Tactin. 2× ST-tag II can be used to construct DNA-protein hybrids.
Camptothecin
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