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Peptide Linkers | Peptides | MedChemExpress

Peptide Linkers Peptide Linkers (26) 1 2 Formula: C196H290BrN55O69.xC2HF3O2 Molecular Weight: 4600.70 (free base) AMG133 peptide payload TFA is a GLP-1 analog agonist peptide. AMG133 peptide payload TFA potently activates GLP-1R and exhibits weight loss and me

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Peptide Linkers

Peptide Linkers (26)

1

2

Formula: C196H290BrN55O69.xC2HF3O2

Molecular Weight: 4600.70 (free base)

AMG133 peptide payload TFA is a GLP-1 analog agonist peptide. AMG133 peptide payload TFA potently activates GLP-1R and exhibits weight loss and metabolic improvement activities. AMG133 peptide payload TFA can be used for the synthesis of AMG 133 (HY-164535).

August 31

Formula: C20H28N4O7

Molecular Weight: 436.46

Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

Formula: C38H64N12O14

Molecular Weight: 912.99

Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide.

Formula: C30H30N4O7

Molecular Weight: 558.58

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit.

Formula: C32H38N6O8

Molecular Weight: 634.68

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

Formula: C24H42N6O7

Molecular Weight: 526.63

PLGLAG is a peptide that serves as the linker in activatable cell-penetrating peptides (ACPPs) and can be used in cancer research.

Formula: C32H54N10O12

Molecular Weight: 770.83

Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar is a decapeptide. Ac-{Gly(N-me)}-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar-Sar can be used to preparation of antibody-drug conjugate.

Formula: C8H14N4O5

Molecular Weight: 246.22

Tetraglycine is a oligopeptide composed of four glycine monomers.

Formula: C31H54N6O11

Molecular Weight: 686.79

Ac-EEVC-OH is a ADC Linker that can be used for the synthesis of ADC molecules.

Formula: C42H81N17O10

Molecular Weight: 984.20

PRRVRLK acetate is a peptide linker. PRRVRLK acetate can be used to make fusion protein.

Formula: C23H21N3O7

Molecular Weight: 451.43

Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker.

Formula: C15H20N4O5

Molecular Weight: 336.34

Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689).

Formula: C60H68F3N11O36S

Molecular Weight: 1608.29

Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.

Formula: C58H67N11O34S

Molecular Weight: 1494.27

Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide and reduces fractured femur healing times.

Formula: C34H39F3N6O10

Molecular Weight: 748.70

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

Formula: C22H36N10O13

Molecular Weight: 648.58

GGGGSGGGGS is a chimeric peptide composed of four peptides. GGGGSGGGGS can efficiently bind to small intestinal submucosa (SIS) membranes. GGGGSGGGGS can be used for research on infectious or inflammatory conditions.

Formula: C38H66N6O13

Molecular Weight: 814.96

Boc-PEG6-Val-Cit-PAB-OH is an ADC linker that can be used for synthesizing antibody-drug conjugates (ADC). Boc-PEG6-Val-Cit-PAB-OH can be used for cancer research.

Formula: C50H84N16O18

Molecular Weight: 1197.30

Ac-pSar16-OH is a polysarcosine which can replace PEG for therapeutic protein conjugation.

Formula: C100H132N26O25.xC2HF3O2

Molecular Weight: 2212.30 (free acid)

2× ST-tag II TFA is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II TFA specifically binds to ST Tactin. 2× ST-tag II TFA can be used to construct DNA-protein hybrids.

Formula: C100H132N26O25

Molecular Weight: 2098.28

2× ST-tag II is an oligopeptide that can link proteins and dsDNA molecules in an efficient, rapid and specific manner. 2× ST-tag II is a peptide ligand of ST Tactin (STN). 2× ST-tag II specifically binds to ST Tactin. 2× ST-tag II can be used to construct DNA-protein hybrids.

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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