Peptide Discovery

Peptides are gathering significant attention not only for their affinity and specificity towards a diverse array of target proteins but also for their tissue permeability (oral suitability) and ease of chemical synthesis. Notably, cyclic peptides that incorporate unnatural amino acids are expected as PPI inhibitors. Additionally, they are anticipated to act as DDS ligands, facilitating the delivery of nucleic acid-based medicines and other drugs to targeted tissues/cells due to their exceptional binding affinity and stability.

Fujifilm offers a comprehensive suite of contract services. Our core offerings include the use of mRNA display technology to discover peptides that bind strongly and specifically to target proteins, combined with rapid structural optimization and activity screening of these hit peptides (e.g., inhibitory activity, selectivity). Additionally, we provide supporting services such as peptide chemical synthesis and the preparation of target proteins.