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PepMix™ Peptide Pool Pan-Melanoma Select Development Grade

PepMix™ Pan-Melanoma Select US$877.50 Excluding tax and shipping fees In stock Description About PepMix™ Pan-Melanoma Select Pool of 115 peptides derived from a peptide scan (Defined HLA class I & II-restricted T-cell epitopes) through Selected proteins of Hum

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

PepMix™ Pan-Melanoma Select

US$877.50

Excluding tax and shipping fees

In stock

Description

About PepMix™ Pan-Melanoma Select

Pool of 115 peptides derived from a peptide scan (Defined HLA class I & II-restricted T-cell epitopes) through Selected proteins of Human.

PepMix™ Pan-Melanoma Select - Specifications

Amount: 15 nmol (approx. 25µg) / peptide for stimulation of 2,5 x 108 cells

Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)

Delivery Format: Freeze-dried in glass vial

Application(s): T-cell Immunity

Condition(s)/Topic(s): Melanoma, Cancer

Standard Delivery Time: 2-5 days

Have a look at further information and publications on Peptide Tools to Study Cancer

Are you interested in your own custom PepMix? Choose your sequence, amount, purity and pool format. We will assist you along the way. Custom PepMix Peptide Pools.

PepMix™ Peptide PoolsProtein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)- In-vitro T cell expansion- Dendritic cell pulsing- Immune monitoring- Cellular immune response profiling- T cell epitope identification- Standardization of T cell assays

Benefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)

References

References for PepMix™ Pan-Melanoma Select

ReferencesRead References with PepMix™ Peptide Pools for Tumor Associated Antigens PepMix™ Control Pools

Application NotesCross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccinationLoyal et al (2021) Full textPeptide Tools to Support the Fight against COVID-19Alem et al (2020) Full textCEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverageEckey et al. (2017) Full textDeveloping Multi-HIV Antigen Specific T-Cells as a Component of a Cure StrategyLam et al. (2015) Full textPeptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell TransplantationGary et al. (2015) Full textPepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell TransplantKeirnan et al. (2012) Full textCytomegalovirus Protein Spanning PepMix™ Peptide Pools to Discover Changes in T-Cell Immunity in the Aging PopulationKern (2012) Full text

Documentation

Documentation for PepMix™ Pan-Melanoma Select

Protocol_PepMix.pdf

PM-Pan-Melanoma-Select-2.pdf

Annotations_Melanoma-Pool-PM-Pan-MELselect.pdf

Properties

Properties of PepMix™ Pan-Melanoma Select

15 nmol (approx. 25µg) / peptide for stimulation of 2,5 x 108 cells, 15 nmol /peptide

T-cell immunity

PepMix Peptide Pools

Cancer, Melanoma

Freeze-dried in glass vial

Human

Selected proteins

No

Further Information to PepMix™ Pan-Melanoma Select

Values

see additional product documentation

Pan Select Peptide Pool

Related Products

Related Products

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PepMix™ HCoV-229E (Spike Glycoprotein)

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US$1,621.10

PepMix™ HCoV-HKU1 (NCAP)

US$574.60

PepMix™ Pan-SARS-CoV-2 Select

US$726.70

PepMix™ Pan-SARS-CoV-2 Select w/o S

US$760.50

PepMix™ SARS-CoV-2 (S-RBD B.1.617.2 / Delta)

US$551.20

PepMix™ SARS-CoV-2 (Spike B.1.617.2 / Delta)

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Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

Research context

Read sources and limitations before applying a claim.

High-Purity Peptides for Accurate Research

Each peptide in the PepMix™ Human (Melan-A/MART-1) pool is purified to development grade with a minimum purity of 70% (HPLC/MS), averaging 85% purity. This high standard ensures that your research results are reliable and reproducible, allowing for precise stimulation and analysis of T-cell responses.

Source: jpt.com ↗

Research Applications

Understanding the role of cellular proteins and HCMV genes in the context of pp65 provides insights into: The mechanisms of immune evasion by HCMV. Development of antiviral strategies targeting pp65. Broader implications for studying opportunistic infections in immunocompromised individuals.

Source: jpt.com ↗
Practical and safety references

These excerpts are educational, not personalised medical instructions.

Potential benefits

Benefits of Using PepMix™ Peptide Pools

When you choose PepMix™ Human MOG1-125 peptide pool, you benefit from: Stringent Quality Control: Each peptide is rigorously tested for identity and purity. Comprehensive Documentation: Certificates of Analysis (CoA) and HPLC-MS data provided for every batch. Batch-to-Batch Consistency: Ensures reliable results across multiple experiments. Elimination of False Positives: Prevents unwanted T-cell responses from contaminating peptides. Minimized Toxicity: Free from toxic inhibitors that could impair T-cell activity. Low Endotoxin Levels: Processed under stringent low-biocontamination conditions. Animal-Derived Component-Free (ADCF) Policy: Ensures compliance with ADCF requirements. HLA-Independent Stimulation: Utilizes antigen-spanning peptide pools for broad applicability.

Source: jpt.com ↗
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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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