PepMix™ Pan-Celiac Disease Select Peptide Pool

PepMix™ Pan-Celiac Disease Select

US$877.50

Excluding tax and shipping fees

In stock

Description

About PepMix™ Pan-Celiac Disease Select

Virus-specific pool of 135 peptides (defined HLA class I & II-restricted T-cell epitopes) from selected proteins of Human for T cell assays (e.g. ELISPOT).

PepMix™ Pan-Celiac Disease Select - Specifications

Amount: 15 nmol (approx. 25µg) / peptide for stimulation of 2,5 x 108 cells

Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)

Delivery Format: Freeze-dried in glass vial

Application(s): T-cell immunity

Condition(s)/Topic(s): Autoimmune disease, Diabetes, Diarrhea

Standard Delivery Time: 2-5 days

PepMix™ Peptide PoolsProtein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)- In-vitro T cell expansion- Dendritic cell pulsing- Immune monitoring- Cellular immune response profiling- T cell epitope identification- Standardization of T cell assays

Benefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)

References

References for PepMix™ Pan-Celiac Disease Select

ReferencesRead References with PepMix™ Peptide Pools for Infectious Diseases COVID-19 related PepMixes™ PepMix™ Control Pools

Application NotesCross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccinationLoyal et al (2021) Full textPeptide Tools to Support the Fight against COVID-19Alem et al (2020) Full textCEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverageEckey et al. (2017) Full textDeveloping Multi-HIV Antigen Specific T-Cells as a Component of a Cure StrategyLam et al. (2015) Full textPeptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell TransplantationGary et al. (2015) Full textPepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell TransplantKeirnan et al. (2012) Full textCytomegalovirus Protein Spanning PepMix™ Peptide Pools to Discover Changes in T-Cell Immunity in the Aging PopulationKern (2012) Full text

Documentation

Documentation for PepMix™ Pan-Celiac Disease Select

Protocol_PepMix.pdf

PM-Pan-Celiac-Disease-Select.pdf

Annotations_Pan-Celiac-Disease-PM-Pan-CELselect.pdf

Properties

Properties of PepMix™ Pan-Celiac Disease Select

15 nmol (approx. 25µg) / peptide for stimulation of 2,5 x 108 cells

T-cell immunity

PepMix Peptide Pools

Autoimmune disease, Diabetes, Diarrhea

Freeze-dried in glass vial

Human

Selected proteins

Development Grade: each peptide purified to > 70% (HPLC/MS)

No

Further Information to PepMix™ Pan-Celiac Disease Select

Values

see additional product documentation

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