Educational guide
PepMix Human Melan-A / MART-1 Overlapping Peptide Pool
PepMix™ Human (Melan-A/MART-1) US$572.00 Excluding tax and shipping fees In stock Description About PepMix™ Human (Melan-A/MART-1) Pool of 27 peptides derived from a peptide scan through Melanoma antigen recognized by T-cells 1 (MART-1) (Swiss-Prot ID: Q16655)
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
PepMix™ Human (Melan-A/MART-1)
US$572.00
Excluding tax and shipping fees
In stock
Description
About PepMix™ Human (Melan-A/MART-1)
Pool of 27 peptides derived from a peptide scan through Melanoma antigen recognized by T-cells 1 (MART-1) (Swiss-Prot ID: Q16655) of Human.
PepMix™ Human (Melan-A/MART-1) - Specifications
Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)
Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)
Delivery Format: Freeze-dried in glass vial
Application(s): T-cell Immunity, Cancer biomarker research
Condition(s)/Topic(s): Cancer, Melanoma
Standard Delivery Time: 2-5 days
Detailed Features of PepMix™ Human (Melan-A/MART-1)
High-Purity Peptides for Accurate Research
Each peptide in the PepMix™ Human (Melan-A/MART-1) pool is purified to development grade with a minimum purity of 70% (HPLC/MS), averaging 85% purity. This high standard ensures that your research results are reliable and reproducible, allowing for precise stimulation and analysis of T-cell responses.
Optimal Quantity for Extensive Research
The pool contains 25 µg (approximately 15 nmol) of each peptide, providing ample material to stimulate up to 2.5 x 108 cells. This quantity is ideal for extensive experimental setups and high-throughput studies, making it suitable for various research applications.
Convenient and Reliable Delivery
The peptides are delivered freeze-dried in a glass vial, which maintains stability and extends shelf life. This format is perfect for long-term storage and ease of use in laboratory settings.
Applications of PepMix™ Human (Melan-A/MART-1)
T-Cell Immunity Studies
MART-1 peptides are instrumental in studying T-cell responses against melanoma cells. The PepMix™ pool enables researchers to explore the effectiveness of potential immunotherapies and understand the immune system's interaction with melanoma antigens.
Cancer Biomarker Research
By using this peptide pool, scientists can investigate the role of Melan-A/MART-1 as a cancer biomarker. It supports research into identifying new biomarkers for melanoma and evaluating their potential in clinical applications.
Research Topics and Conditions
Focus on Melanoma
The PepMix™ Human (Melan-A/MART-1) is specifically designed to address melanoma, a serious skin cancer. It provides valuable insights into the antigenic targets of melanoma, facilitating advancements in targeted therapies.
Customizing Your Peptide Pool
If you require a personalized peptide pool, we offer customization options. You can choose specific peptide sequences, adjust the amount, select the desired purity, and decide on the format that best suits your research needs. Our team is available to guide you through the customization process and ensure your specifications are met.
Benefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)
References
References for PepMix™ Human (Melan-A/MART-1)
ReferencesRead References with PepMix™ Peptide Pools for Tumor Associated Antigens PepMix™ Control Pools
Application NotesCross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccinationLoyal et al (2021) Full textPeptide Tools to Support the Fight against COVID-19Alem et al (2020) Full textCEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverageEckey et al. (2017) Full textDeveloping Multi-HIV Antigen Specific T-Cells as a Component of a Cure StrategyLam et al. (2015) Full textPeptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell TransplantationGary et al. (2015) Full textPepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell TransplantKeirnan et al. (2012) Full textCytomegalovirus Protein Spanning PepMix™ Peptide Pools to Discover Changes in T-Cell Immunity in the Aging PopulationKern (2012) Full text
Documentation
Documentation for PepMix™ Human (Melan-A/MART-1)
Protocol_PepMix.pdf
PM-Melan-A-MART-1.pdf
Properties
Properties of PepMix™ Human (Melan-A/MART-1)
25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)
Cancer biomarker research, T-cell immunity
PepMix Peptide Pools, PepMix Peptide Pools TAA
Cancer, Melanoma
Freeze-dried in glass vial
Human
Melanoma antigen recognized by T-cells 1 (MART-1)
>70% (HPLC-MS), Development Grade: each peptide purified to > 70% (HPLC/MS)
No
Further Information to PepMix™ Human (Melan-A/MART-1)
Values
MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP Copy Sequence Show complete Sequence Show trimmed Sequence
Peptide scan (15mers with 11 aa overlap)
Related Products
Related Products
PepMix™ Human (MAGEA1)
US$646.10
PepMix™ Human (MAGEA3)
US$617.50
PepMix™ Human (MAGEA4)
PepMix™ Human (Prame/OIP4)
US$603.20
PepStar™ Human (MAGEA1)
US$157.30
PepStar™ Human (MAGEA3)
PepStar™ Human (MAGEA4)
PepStar™ Human (Melan-A/MART-1)
PepStar™ Human (Prame/OIP4)
US$239.20
US$1,027.00