PepMix AAV8 (Capsid protein) Overlapping Peptide Pool

PepMix™ AAV8 (Capsid protein)

US$715.00

Excluding tax and shipping fees

In stock

Description

About PepMix™ AAV8 (Capsid protein)

Pool of 182 peptides derived from a peptide scan (15mers with 11 aa overlap) through Capsid protein (Swiss-Prot ID: Q8JQF8) of Adeno-Associated Virus (AAV) - type 8.

PepMix™ AAV8 (Capsid protein) - Specifications

Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)

Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)

Delivery Format: Freeze-dried in glass vial

Application(s): T-cell Immunity

Condition(s)/Topic(s): Cancer, Gene therapy, Infection

Standard Delivery Time: 2-5 days

For researchers involved in gene therapy vectors and related tools, this product provides robust and reliable performance across a variety of assays. Learn more about our Gene Therapy Vectors & Tools.

Custom PepMix™ Options for AAV8 and Beyond

Are you interested in designing your own custom PepMix™? With our custom peptide pool service, you have the freedom to choose the sequence, amount, purity, and pool format that best fits your research. Our team provides personalized support to ensure your custom PepMix™ peptide pool meets your specific research requirements. Explore Custom PepMix Peptide Pools.

PepMix™ peptide pools, including our AAV8 Capsid protein, are engineered for versatility and precision in antigen-specific T cell stimulation. They are especially useful for immune profiling, epitope mapping, and T cell-based assays. Key applications include:

Antigen-specific T cell stimulation: Ideal for assays like ELISpot, ICS, and cytotoxicity assays

In-vitro T cell expansion: Supports robust T cell growth in controlled environments

Dendritic cell pulsing: Enhances T cell presentation and activation

Immune monitoring and profiling: Tracks immune response patterns across various applications

T cell epitope identification: Maps out immune targets for further study

Standardization of T cell assays: Ensures consistent results in immunological testing

Our PepMix™ peptide pools, like the AAV8 (Capsid protein), are meticulously quality controlled, offering:

High Purity and Quality: Every peptide is purified and identity-verified through HPLC-MS analysis.

Reliability and Consistency: Batch-to-batch reproducibility ensures consistent results.

Contaminant-Free Formulation: Stringent purification and low bioburden processing minimize contamination risks.

ADCF Compliance: Complies with Animal-Derived Component-Free standards.

HLA Independence: Provides HLA-independent stimulation for broad immune reactivity.

These benefits make our PepMix™ AAV8 peptide pool ideal for researchers seeking reliable and high-purity peptide pools for their T-cell assays.

References

References for PepMix™ AAV8 (Capsid protein)

ReferencesRead References with PepMix™ Peptide Pools for Infectious Diseases COVID-19 related PepMixes™ PepMix™ Control Pools

Application NotesCross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccinationLoyal et al (2021) Full textPeptide Tools to Support the Fight against COVID-19Alem et al (2020) Full textCEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverageEckey et al. (2017) Full textDeveloping Multi-HIV Antigen Specific T-Cells as a Component of a Cure StrategyLam et al. (2015) Full textPeptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell TransplantationGary et al. (2015) Full textPepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell TransplantKeirnan et al. (2012) Full textCytomegalovirus Protein Spanning PepMix™ Peptide Pools to Discover Changes in T-Cell Immunity in the Aging PopulationKern (2012) Full text

Testimonials "To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our go-to company for purchasing peptides." Dr. Laura J Pallett, Infection and Immunity, University College London, UK

Documentation

Documentation for PepMix™ AAV8 (Capsid protein)

Protocol_PepMix.pdf

PM-AAV8-Capsid-protein.pdf

Properties

Properties of PepMix™ AAV8 (Capsid protein)

25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)

T-cell immunity

PepMix Peptide Pools, PepMix Peptide Pools Infections

Cancer, Gene therapy, Infection

Freeze-dried in glass vial

Adeno-Associated Virus (AAV)

Capsid protein

>70% (HPLC-MS), Development Grade: each peptide purified to > 70% (HPLC/MS)

No

Further Information to PepMix™ AAV8 (Capsid protein)

Values

MAADGYLPDWLEDNLSEGIREWWALKPGAPKPKANQQKQDDGRGLVLPGYKYLGPFNGLDKGEPVNAADAAALEHDKAYDQQLQAGDNPYLRYNHADAEFQERLQEDTSFGGNLGRAVFQAKKRVLEPLGLVEEGAKTAPGKKRPVEPSPQRSPDSSTGIGKKGQQPARKRLNFGQTGDSESVPDPQPLGEPPAAPSGVGPNTMAAGGGAPMADNNEGADGVGSSSGNWHCDSTWLGDRVITTSTRTWALPTYNNHLYKQISNGTSGGATNDNTYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTIQVFTDSEYQLPYVLGSAHQGCLPPFPADVFMIPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFQFTYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTQTTGGTANTQTLGFSQGGPNTMANQAKNWLPGPCYRQQRVSTTTGQNNNSNFAWTAGTKYHLNGRNSLANPGIAMATHKDDEERFFPSNGILIFGKQNAARDNADYSDVMLTSEEEIKTTNPVATEEYGIVADNLQQQNTAPQIGTVNSQGALPGMVWQNRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGLKHPPPQILIKNTPVPADPPTTFNQSKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSTSVDFAVNTEGVYSEPRPIGTRYLTRNL Copy Sequence Show complete Sequence Show trimmed Sequence

Peptide scan (15mers with 11 aa overlap)

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