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Peach & Lily MiniProtein Exosome Bioactive Ampoule Versus DRMTLGY Needle-less Growth Factor Serum

Peach & Lily MiniProtein Exosome Bioactive Ampoule Versus DRMTLGY Needle-less Growth Factor Serum This anti-aging ampoule is formulated around Copper Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier. This anti-aging serum is formulat

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Peach & Lily MiniProtein Exosome Bioactive Ampoule Versus DRMTLGY Needle-less Growth Factor Serum

This anti-aging ampoule is formulated around Copper Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier.

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dicaprylyl Ether

Butylene Glycol

Coco-Caprylate/Caprate

Glycerin

Pentaerythrityl Tetraisostearate

Dicaprylyl Carbonate

1,2-Hexanediol

Caprylic/Capric Triglyceride

Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate

Hydrolyzed Rice Protein

Glycine Soja Protein

Acetyl Sh-Hexapeptide-5 Amide Acetate

Centella Asiatica Leaf Extract

Linoleic Acid

Linolenic Acid

Swertia Chirata Extract

Glycine

Serine

Glutamic Acid

Leucine

Alanine

Lysine

Arginine

Tyrosine

Hexapeptide-9

Acetyl Tetrapeptide-5

Acetyl Tetrapeptide-2

Palmitoyl Pentapeptide-4

Tripeptide-1

Hexapeptide-11

Acetyl Hexapeptide-8

Copper Tripeptide-1

Alanine/Histidine/Lysine Polypeptide Copper Hcl

Argania Spinosa Kernel Oil

Tripeptide-32

Palmitoyl Tetrapeptide-7

Scutellaria Baicalensis Root Extract

Polygonum Multiflorum Root Extract

Sophora Flavescens Root Extract

Cimicifuga Racemosa Root Extract

Phenylalanine

Valine

Proline

Threonine

Aspartic Acid

Isoleucine

Histidine

Methionine

Cysteine

Dextrin Palmitate

Superoxide Dismutase

Glycyrrhiza Glabra Root Extract

Angelica Gigas Root Extract

Adenosine

Morus Alba Bark Extract

Phellinus Linteus Extract

Dioscorea Opposita Root Extract

Paeonia Albiflora Root Extract

Sesamum Indicum Seed Extract

Sodium Dextran Sulfate

Polyglyceryl-4 Oleate

Disteardimonium Hectorite

Polyglyceryl-6 Oleate

Polyhydroxystearic Acid

Propylene Carbonate

Cellulose Gum

Polyglyceryl-10 Laurate

Ethylhexylglycerin

Tocopherol

Sodium Phytate

Caprylyl Glycol

Pentylene Glycol

Sodium Benzoate

Maltodextrin

Sodium Chloride

Water, Dicaprylyl Ether, Butylene Glycol, Coco-Caprylate/Caprate, Glycerin, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate, Hydrolyzed Rice Protein, Glycine Soja Protein, Acetyl Sh-Hexapeptide-5 Amide Acetate, Centella Asiatica Leaf Extract, Linoleic Acid, Linolenic Acid, Swertia Chirata Extract, Glycine, Serine, Glutamic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Hexapeptide-9, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-2, Palmitoyl Pentapeptide-4, Tripeptide-1, Hexapeptide-11, Acetyl Hexapeptide-8, Copper Tripeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Argania Spinosa Kernel Oil, Tripeptide-32, Palmitoyl Tetrapeptide-7, Scutellaria Baicalensis Root Extract, Polygonum Multiflorum Root Extract, Sophora Flavescens Root Extract, Cimicifuga Racemosa Root Extract, Phenylalanine, Valine, Proline, Threonine, Aspartic Acid, Isoleucine, Histidine, Methionine, Cysteine, Dextrin Palmitate, Superoxide Dismutase, Glycyrrhiza Glabra Root Extract, Angelica Gigas Root Extract, Adenosine, Morus Alba Bark Extract, Phellinus Linteus Extract, Dioscorea Opposita Root Extract, Paeonia Albiflora Root Extract, Sesamum Indicum Seed Extract, Sodium Dextran Sulfate, Polyglyceryl-4 Oleate, Disteardimonium Hectorite, Polyglyceryl-6 Oleate, Polyhydroxystearic Acid, Propylene Carbonate, Cellulose Gum, Polyglyceryl-10 Laurate, Ethylhexylglycerin, Tocopherol, Sodium Phytate, Caprylyl Glycol, Pentylene Glycol, Sodium Benzoate, Maltodextrin, Sodium Chloride

Saccharide Isomerate

Sodium Hyaluronate

Palmitoyl Tripeptide-1

Oligopeptide-3

Oligopeptide-2

Oligopeptide-1

Palmitoyl Tripeptide-5

Ceramide NP

Folic Acid

Phytosphingosine

Ceramide AP

Ceramide EOP

Triheptanoin

Phenoxyethanol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

C9-12 Alkane

Polyurethane-100

Sodium Hydroxide

Lecithin

Trisodium Ethylenediamine Disuccinate

Acetyl Glutamine

Tremella Fuciformis Sporocarp Extract

Hydrolyzed Hyaluronic Acid

Decyl Glucoside

Bacillus/Soybean Ferment Extract

Sodium Lauroyl Lactylate

Carbomer

Polysorbate 20

Cholesterol

Xanthan Gum

Water, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Swertia Chirata Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Tremella Fuciformis Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Coco-Caprylate/Caprate is a lightweight ester created from coconut oil fatty acids, caprylic acid, and capric acid.

It is an emollient that helps soften skin and reduce transepidermal water loss (TEWL). What sets it apart from heavier emollients is its ultralight, non-greasy feel.

Once applied, this ingredient dries down quickly and leaves a dry, silky finish behind. This also helps improve spreadability and texture.

This ingredient has an excellent safety-record and is non-irritating.

Typical concentrations for cosmetics range from 0.5-62%.

Research on Malassezia growth found no growth on fatty acid esters with chain lengths shorter than 12 carbons (it prefers C11-24).

Since Coco-Caprylate/Caprate is built on C8 and C10 fatty acids, it is out of the range that Malassezia metabolizes, and therefore safe for fungal acne.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This synthetic peptide is known as a signal peptide. Signal peptides tell your skin to create more collagen, elastin and protein.

Hexapeptide-11 is composed of several amino acids, including alanine.

Maltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.

This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).

Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.

Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

We don't have a description for Swertia Chirata Extract yet.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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