Educational guide
Parathyroid Hormone-Related Peptide (PTHrP) by LC-MS/MS ...
Ordering Recommendation Recommendations when to order or not order the test. May include related or preferred tests. Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Ordering Recommendation
Recommendations when to order or not order the test. May include related or preferred tests.
Aid in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662), available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at (800) 522-2787. A winged collection set must be used.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Mix well. Separate from cells within 1 hour of collection. Transfer 1.5 mL plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Frozen. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Grossly hemolyzed specimens.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months
Methodology
Process(es) used to perform the test.
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Days of the week the test is performed.
Sun, Mon, Wed, Fri
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
2-6 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
| Age | Male |
Female |
|---|---|---|
| Under 18 years | Not established | Not established |
| 18 years and older | 0.0-2.3 pmol/L | 0.0-3.4 pmol/L |
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Compliance Category
Laboratory Developed Test (LDT)
Note
Additional information related to the test.
Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually.
CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ.
CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
82542
Components
Components of test
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0093016 | PTHrP by LC-MS/MS, Plasma | 15087-0 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
- HHM
- Humoral Hypercalcemia of Malignancy Factor
- Parathyroid Hormone Related Peptide
- Parathyroid Hormone Related Protein
- Parathyroid Related Polypeptide
- Parathyroid Related Protein
- PRP
- PTH Related Peptide
- PTH Related Protein
- PTH-RP
- PTHrP secretion
- PTHRP, Plasma
Parathyroid Hormone-Related Peptide (PTHrP) by LC-MS/MS, Plasma