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OSEA Blemish Balm Versus Biossance Squalane + Omega Repair Cream

OSEA Blemish Balm Versus Biossance Squalane + Omega Repair Cream This acne moisturizer is formulated around Melaleuca Alternifolia Leaf Oil to clear breakouts and balance excess oil. This barrier-repair moisturizer is formulated around Squalane and Ceramide NP

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

OSEA Blemish Balm Versus Biossance Squalane + Omega Repair Cream

This acne moisturizer is formulated around Melaleuca Alternifolia Leaf Oil to clear breakouts and balance excess oil.

This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Gigartina Skottsbergii Extract

Macrocystis Pyrifera

Algae

Undaria Pinnatifida Vesicles

Vitis Vinifera Seed Oil

Caprylic/Capric Triglyceride

Glycerin

Propanediol

Cetearyl Olivate

Simmondsia Chinensis Seed Oil

Sorbitan Olivate

Melaleuca Alternifolia Leaf Oil

Saccharomyces/Copper Ferment

Rosmarinus Officinalis Leaf Oil

Saccharomyces/Manganese Ferment

Lavandula Angustifolia Oil

Saccharomyces/Zinc Ferment

Myrtus Communis Leaf Oil

Glyceryl Stearate

Thymus Vulgaris Oil

Cetearyl Alcohol

Cupressus Sempervirens Oil

Stearic Acid

Citrus Grandis Peel Oil

Sodium Lauroyl Glutamate

Xanthan Gum

Cyamopsis Tetragonoloba Gum

Citric Acid

Lonicera Caprifolium Extract

Lonicera Japonica Callus Extract

Water, Gigartina Skottsbergii Extract, Macrocystis Pyrifera, Algae, Undaria Pinnatifida Vesicles, Vitis Vinifera Seed Oil, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Cetearyl Olivate, Simmondsia Chinensis Seed Oil, Sorbitan Olivate, Melaleuca Alternifolia Leaf Oil, Saccharomyces/Copper Ferment, Rosmarinus Officinalis Leaf Oil, Saccharomyces/Manganese Ferment, Lavandula Angustifolia Oil, Saccharomyces/Zinc Ferment, Myrtus Communis Leaf Oil, Glyceryl Stearate, Thymus Vulgaris Oil, Cetearyl Alcohol, Cupressus Sempervirens Oil, Stearic Acid, Citrus Grandis Peel Oil, Sodium Lauroyl Glutamate, Xanthan Gum, Cyamopsis Tetragonoloba Gum, Citric Acid, Lonicera Caprifolium Extract, Lonicera Japonica Callus Extract

Squalane

Isoamyl Laurate

Butyrospermum Parkii Butter

Ceramide NP

Jojoba Esters

Sodium Hyaluronate

Euterpe Oleracea Sterols

Linoleic Acid

Oleic Acid

Linolenic Acid

Ethyl Linoleate

Tocopherol

Isoamyl Cocoate

Cetyl Palmitate

Sorbitan Palmitate

Ethylhexylglycerin

Carbomer

Sodium Hydroxide

Phenoxyethanol

Sodium Gluconate

Water, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Cetearyl Olivate is a plant-derived emulsifier and texture enhancer. It helps keep the oil and water phases from separating so your formulas stay stable.

You'll likely see it combined with Sorbitan Olivate (together sold as the trade name Olivem 1000). This combination generates a liquid crystal structure that closely resemble the lipid organization of the stratum corneum.

These "skin-like" liquid crystals improve skin barrier integrity and promote the delivery of actives into the skin.

This ingredient is well-tolerated and has no significant sensitization data.

Because it is derived from the fatty acids in olive oil, this ingredient may not be fungal acne safe.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.

According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.

Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.

Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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