Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

Olehenriksen Truth Serum Versus Biossance Squalane + Phyto-Retinol Serum

Olehenriksen Truth Serum Versus Biossance Squalane + Phyto-Retinol Serum This brightening serum is formulated around Sodium Ascorbyl Phosphate to brighten dull-looking skin. This anti-aging serum is formulated around Squalane and Niacinamide to soften the look

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Olehenriksen Truth Serum Versus Biossance Squalane + Phyto-Retinol Serum

This brightening serum is formulated around Sodium Ascorbyl Phosphate to brighten dull-looking skin.

This anti-aging serum is formulated around Squalane and Niacinamide to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Oleth-20

Sodium Ascorbyl Phosphate

Hydroxyethylcellulose

Phenoxyethanol

Caprylyl Glycol

Hexylene Glycol

Citric Acid

Parfum

PEG-12 Dimethicone

Tocopheryl Acetate

Aroma

Hydrolyzed Vegetable Protein

Disodium Phosphate

Polysorbate 60

Aloe Barbadensis Leaf Extract

Citrus Aurantium Dulcis Fruit Extract

Sodium Hyaluronate

Thioctic Acid

Calcium Ascorbate

Sodium Phosphate

Sorbitol

Citrus Grandis Seed Extract

Sodium Benzoate

Ascorbic Acid

Camellia Sinensis Leaf Extract

Euphrasia Officinalis Extract

Rosa Canina Fruit Extract

Leuconostoc/Radish Root Ferment Filtrate

Potassium Sorbate

Triacetin

Sodium Benzotriazolyl Butylphenol Sulfonate

Benzyl Benzoate

Limonene

Linalool

CI 15985

Water, Glycerin, Oleth-20, Sodium Ascorbyl Phosphate, Hydroxyethylcellulose, Phenoxyethanol, Caprylyl Glycol, Hexylene Glycol, Citric Acid, Parfum, PEG-12 Dimethicone, Tocopheryl Acetate, Aroma, Hydrolyzed Vegetable Protein, Disodium Phosphate, Polysorbate 60, Aloe Barbadensis Leaf Extract, Citrus Aurantium Dulcis Fruit Extract, Sodium Hyaluronate, Thioctic Acid, Calcium Ascorbate, Sodium Phosphate, Sorbitol, Citrus Grandis Seed Extract, Sodium Benzoate, Ascorbic Acid, Camellia Sinensis Leaf Extract, Euphrasia Officinalis Extract, Rosa Canina Fruit Extract, Leuconostoc/Radish Root Ferment Filtrate, Potassium Sorbate, Triacetin, Sodium Benzotriazolyl Butylphenol Sulfonate, Benzyl Benzoate, Limonene, Linalool, CI 15985

Squalane

Niacinamide

Sodium Acrylates Copolymer

Bakuchiol

Rosa Canina Fruit Oil

Citrus Aurantium Amara Peel Oil

Biosaccharide Gum-1

Yeast Extract

Soy Amino Acids

Lecithin

Ethylhexylglycerin

Tetrasodium Glutamate Diacetate

Geraniol

Water, Squalane, Niacinamide, Sodium Acrylates Copolymer, Bakuchiol, Sodium Hyaluronate, Rosa Canina Fruit Oil, Citrus Aurantium Amara Peel Oil, Biosaccharide Gum-1, Yeast Extract, Soy Amino Acids, Lecithin, Hexylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol, Tetrasodium Glutamate Diacetate, Citric Acid, Linalool, Geraniol, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Limonene is a fragrance that adds scent and taste to a formulation.

It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.

This ingredient has a scent that is floral, spicy tropical, and citrus-like.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →