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Olehenriksen Nurture Me Moisturizing Crème Versus Biossance Squalane + Probiotic Gel Moisturizer

Olehenriksen Nurture Me Moisturizing Crème Versus Biossance Squalane + Probiotic Gel Moisturizer This day moisturizer is formulated around Helianthus Annuus Seed Oil and Rosa Canina Fruit Oil to hydrate skin. This barrier-repair moisturizer is formulated aroun

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Olehenriksen Nurture Me Moisturizing Crème Versus Biossance Squalane + Probiotic Gel Moisturizer

This day moisturizer is formulated around Helianthus Annuus Seed Oil and Rosa Canina Fruit Oil to hydrate skin.

This barrier-repair moisturizer is formulated around Squalane to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Helianthus Annuus Seed Oil

Glycerin

Dimethicone

Glyceryl Stearate Se

Cyclopentasiloxane

Rosa Canina Fruit Oil

Cetearyl Alcohol

Cetyl Alcohol

Parfum

Ceteareth-20

Phenoxyethanol

Oenothera Biennis Oil

Allantoin

Triticum Vulgare Germ Oil

Carbomer

Panthenol

Caprylyl Glycol

Hexylene Glycol

Ethylhexylglycerin

Ethylhexyl Methoxycinnamate

Tocopheryl Acetate

Citrus Grandis Fruit Extract

Citrus Aurantium Dulcis Fruit Extract

Chamomilla Recutita Flower Extract

Calendula Officinalis Flower Extract

Retinyl Palmitate

Citric Acid

Tocopherol

CI 15985

Ascorbyl Palmitate

CI 16035

BHT

Benzyl Benzoate

Citral

Limonene

Linalool

Water, Helianthus Annuus Seed Oil, Glycerin, Dimethicone, Glyceryl Stearate Se, Cyclopentasiloxane, Rosa Canina Fruit Oil, Cetearyl Alcohol, Cetyl Alcohol, Parfum, Ceteareth-20, Phenoxyethanol, Oenothera Biennis Oil, Allantoin, Triticum Vulgare Germ Oil, Carbomer, Panthenol, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Ethylhexyl Methoxycinnamate, Tocopheryl Acetate, Citrus Grandis Fruit Extract, Citrus Aurantium Dulcis Fruit Extract, Chamomilla Recutita Flower Extract, Calendula Officinalis Flower Extract, Retinyl Palmitate, Citric Acid, Tocopherol, CI 15985, Ascorbyl Palmitate, CI 16035, BHT, Benzyl Benzoate, Citral, Limonene, Linalool

Squalane

Lepidium Sativum Sprout Extract

Sodium Acrylates Copolymer

Caprylic/Capric Triglyceride

Capryloyl Glycerin/Sebacic Acid Copolymer

Lecithin

Diheptyl Succinate

Isoeicosane

Bisabolol

Sodium Phytate

Glycine Soja Sterols

Linoleic Acid

Phospholipids

Hansenula/Kloeckera/Lactobacillus/Lactococcus/Leuconostoc/Pediococcus/Saccharomyces/Fig/Lemon Ferment

Chondrus Crispus Extract

Sorbitan Oleate

Cellulose Gum

Chitosan

1,2-Hexanediol

Sodium Hyaluronate

Potassium Sorbate

Water, Glycerin, Squalane, Lepidium Sativum Sprout Extract, Sodium Acrylates Copolymer, Caprylic/Capric Triglyceride, Phenoxyethanol, Capryloyl Glycerin/Sebacic Acid Copolymer, Lecithin, Caprylyl Glycol, Diheptyl Succinate, Isoeicosane, Allantoin, Bisabolol, Sodium Phytate, Glycine Soja Sterols, Linoleic Acid, Phospholipids, Hansenula/Kloeckera/Lactobacillus/Lactococcus/Leuconostoc/Pediococcus/Saccharomyces/Fig/Lemon Ferment, Chondrus Crispus Extract, Sorbitan Oleate, Cellulose Gum, Chitosan, 1,2-Hexanediol, Sodium Hyaluronate, Citric Acid, Potassium Sorbate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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