Myrbetriq (Mirabegron): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Key Takeaways

• Myrbetriq is used to help with overactive bladder symptoms, such as urine leakage, wetting accidents, and needing to pee often or urgently.
• It is also used to treat a bladder condition caused by brain or nerve problems.
• Myrbetriq works by relaxing bladder muscles to help your bladder hold more urine.
• Common side effects include high blood pressure, headache, common cold symptoms, and bladder infections.
• Call your health care provider right away if you are unable to pee or have trouble emptying your bladder.

Uses

What is Myrbetriq used for?

Myrbetriq (mirabegron) is commonly used for the following conditions.

• Overactive Bladder. Overactive bladder (OAB) is a condition that makes you feel like you need to pee even though your bladder is not full. Myrbetriq is used when you have a strong need to pee right away, wetting accidents because of a strong need to pee, or frequent peeing.
• Neurogenic Detrusor Overactivity. Neurogenic detrusor overactivity (NDO) is when the muscle in your bladder is too active, so the amount of pee your bladder can hold is lowered. NDO is a type of neurogenic bladder condition caused by brain, spinal cord, or nerve problems.

Myrbetriq may also be used for other conditions as determined by your health care provider.

How does Myrbetriq work (mechanism of action)?

Myrbetriq increases the amount of pee that your bladder can hold by relaxing a muscle in your bladder.

How is Myrbetriq supplied (dosage forms)?

Myrbetriq is available in the following dosage forms that are taken by mouth.

• 25 mg extended-release oral tablets
• 50 mg extended-release oral tablets
• 8 mg/mL extended-release oral suspension

How should I store Myrbetriq?

Oral Tablets. Myrbetriq oral tablets should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C), for shorter periods of time, such as when transporting it. Oral Liquid. Myrbetriq oral liquid should be stored between 68 F to 77 F (20 C to 25 C) for up to 28 days. Throw away unused medicine after 28 days.

Side Effects

What are the most common side effects of Myrbetriq?

The most common side effects of Myrbetriq are listed below. Tell your health care provider if you have any of the following side effects.

• High blood pressure (see below)
• Infection in the nose or throat, sore throat, or common cold symptoms
• Kidney or bladder infection
• Headache
• Constipation
• Fast heartbeat (when used with solifenacin)
• Dry mouth (when used with solifenacin)

There may be other side effects of Myrbetriq that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

What are the serious side effects of Myrbetriq?

While less common, the most serious side effects of Myrbetriq are described below, along with what to do if they happen. Severe Allergic Reactions. Myrbetriq can cause allergic reactions, which can be serious. Stop using Myrbetriq and get help right away if you have any of the following symptoms of a serious allergic reaction.

• Breathing problems or wheezing
• Racing heart
• Fever or general ill feeling
• Swollen lymph nodes
• Swelling of the face, lips, mouth, tongue, or throat
• Trouble swallowing or throat tightness
• Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
• Nausea or vomiting
• Dizziness, feeling lightheaded, or fainting
• Stomach cramps
• Joint pain

Angioedema. Myrbetriq may cause a certain type of allergic reaction called angioedema. The usual symptoms of this reaction include swelling of the lips, face, tongue, or throat. Stop using the medicine and contact your health care provider if you have this type of swelling. If it is causing problems breathing, seek immediate medical attention.

Increased Blood Pressure (Hypertension). Myrbetriq may increase your blood pressure or make it worse if you have a history of high blood pressure. Call your health care provider if your blood pressure increases while taking this medicine.

If you measure your blood pressure and the top number (systolic) is 180 mm Hg or higher or the bottom number (diastolic) is 120 mm Hg or higher, get medical attention right away. Increases in blood pressure may not be noticeable but look out for any of the following symptoms of severely high blood pressure.

• Sudden severe headache
• Chest pain
• Dizziness or confusion
• Trouble breathing
• Nausea/vomiting
• Blurry or other changes to vision
• Anxiety
• Buzzing in the ears
• Nosebleed
• Feeling of skipped heart beats

Inability to Empty Bladder (Urinary Retention). Myrbetriq may increase the risk of an inability to empty your bladder if you have a blockage in your bladder or if you are taking other medicines like solifenacin to treat overactive bladder. Tell your health care provider right away if you are unable to pee or cannot make a normal amount of pee.

Warnings & Precautions

Who should not take Myrbetriq?

Allergies to Ingredients. People who are allergic to any of the following should not take Myrbetriq.

• Myrbetriq
• Mirabegron
• Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in Myrbetriq.

Kidney Problems. Myrbetriq should not be used if your kidneys are not working as well as they should be or if you are on dialysis. If there is a concern about the health of your kidneys, your health care provider may do tests to determine if they are working well enough to take this medicine.

Liver Problems. Myrbetriq should not be used if your liver is not working as well as it should be. If there is a concern about the health of your liver, your health care provider may do tests to determine if it is working well enough to take this medicine.

What should I know about Myrbetriq before taking it?

Do not take Myrbetriq unless it has been prescribed to you by a health care provider. Take it as prescribed. Do not share Myrbetriq with other people, even if they have the same condition as you. It may harm them. Keep Myrbetriq out of the reach of children. Do not chew, cut, or crush Myrbetriq oral tablets. Children need to take Myrbetriq oral tablets or liquid with food. Vigorously shake Myrbetriq liquid for at least 1 minute and wait until the foam on top goes away before each use. Use an accurate measuring device to measure your dose. A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Ask your pharmacist what measuring device to use.

What should I tell my health care provider before taking Myrbetriq?

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Myrbetriq is right for you. In particular, make sure that you discuss any of the following. Current and Past Health Conditions. Tell your health care provider if you have any of the following.

• High blood pressure (hypertension)
• Kidney or liver problems
• Problems peeing, a weak urine stream, or a blockage in your bladder

Other Medicines and Supplements. Myrbetriq may interact with other medicines and supplements. Before using Myrbetriq, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section below for more details.

Pregnancy. It is not known if or how Myrbetriq could affect pregnancy or harm a fetus. Tell your health care provider if you are or plan to become pregnant.

Breastfeeding. It is not known if Myrbetriq passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed.

How can I get more information about Myrbetriq?

For more information about Myrbetriq, you can visit the manufacturer’s website at www.myrbetriq.com or call them at 800-727-7003.

Interactions

Does Myrbetriq interact with foods or drinks?

There are no known interactions between Myrbetriq and foods or drinks. It is unknown if drinking alcohol will affect Myrbetriq. The risk of dizziness may be increased if you drink alcohol while taking Myrbetriq.

Does Myrbetriq interact with other medicines?

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure that you discuss if you are using any of the following before using Myrbetriq.

• Digoxin (Lanoxin), which is a medicine to treat heart failure and abnormal heart rhythms
• Flecainide (Tambocor) or propafenone (Rythmol), which are medicines used for abnormal heart rhythms
• Warfarin (Coumadin, Jantoven), which is a medicine to treat or prevent blood clots
• Thioridazine (Mellaril), which is a medicine used for some mental health conditions
• Solifenacin (VESIcare), which is a medicine for overactive bladder (OAB)

Myrbetriq may alter the blood levels of some other medicines. Tell your health care provider about all medicines that you take or have recently taken.

This may not be a complete list of medicines that can interact with Myrbetriq. Always check with your health care provider.

Overdose/Missed Dose

What should I do if I accidentally take too much Myrbetriq?

If you or someone else has used too much Myrbetriq, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

What should I do if I miss a dose of Myrbetriq?

If you miss a dose, take it as soon as you remember. If more than 12 hours have passed since your last dose, skip the missed dose and only take the next dose at the usual time. Do not take double or extra doses.

Are you currently using Myrbetriq (Mirabegron)?

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