Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

Murad Daily Defense Colloidal Oatmeal Cream Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

Murad Daily Defense Colloidal Oatmeal Cream Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer This calming moisturizer is formulated around Colloidal Oatmeal and Avena Sativa Kernel Extract to calm redness and strengthen the skin barrier. This bar

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Murad Daily Defense Colloidal Oatmeal Cream Versus Summer Fridays Cloud Dew Oil-Free Gel Cream Moisturizer

This calming moisturizer is formulated around Colloidal Oatmeal and Avena Sativa Kernel Extract to calm redness and strengthen the skin barrier.

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Colloidal Oatmeal 1%

Water

Glycerin

Butyrospermum Parkii Butter

Propanediol

Caprylic/Capric Triglyceride

Glyceryl Stearate

Avena Sativa Kernel Flour

Avena Sativa Kernel Extract

Betaine

Ophiopogon Japonicus Root Extract

Niacinamide

Hydrogenated Lecithin

Ethylhexylglycerin

Maltodextrin

Cetearyl Alcohol

Cetearyl Glucoside

Lauryl Laurate

Cetyl Myristate

Sodium Polyacrylate Starch

Carbomer

Hectorite

Caprylhydroxamic Acid

Tetrasodium Glutamate Diacetate

Sodium Hydroxide

Chlorphenesin

Colloidal Oatmeal 1%, Water, Glycerin, Butyrospermum Parkii Butter, Propanediol, Caprylic/Capric Triglyceride, Glyceryl Stearate, Avena Sativa Kernel Flour, Avena Sativa Kernel Extract, Betaine, Ophiopogon Japonicus Root Extract, Niacinamide, Hydrogenated Lecithin, Ethylhexylglycerin, Maltodextrin, Cetearyl Alcohol, Cetearyl Glucoside, Lauryl Laurate, Cetyl Myristate, Sodium Polyacrylate Starch, Carbomer, Hectorite, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Chlorphenesin

Dicaprylyl Carbonate

Pentylene Glycol

Sodium Hyaluronate

Hydrolyzed Sodium Hyaluronate

Glycine

Serine

Glutamic Acid

Aspartic Acid

Leucine

Alanine

Lysine

Arginine

Tyrosine

Phenylalanine

Proline

Threonine

Valine

Isoleucine

Histidine

Ascorbic Acid

Saccharide Isomerate

Haematococcus Pluvialis Extract

Ceramide NP

Tocopheryl Acetate

Tocopherol

Hexapeptide-11

Palmitoyl Tripeptide-1

Ananas Sativus Fruit Extract

Saccharomyces/Magnesium Ferment

Saccharomyces/Copper Ferment

Saccharomyces/Silicon Ferment

Butylene Glycol

Glyceryl Acrylate/Acrylic Acid Copolymer

Glyceryl Caprylate

Sucrose Stearate

Lecithin

Polyglyceryl-10 Laurate

Xanthan Gum

Cetearyl Olivate

Sorbitan Olivate

Sodium Citrate

Citric Acid

Lactobacillus Ferment

Leuconostoc/Radish Root Ferment Filtrate

Hydroxyacetophenone

CI 77491

Water, Propanediol, Dicaprylyl Carbonate, Glycerin, Pentylene Glycol, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Ascorbic Acid, Saccharide Isomerate, Haematococcus Pluvialis Extract, Ceramide NP, Tocopheryl Acetate, Tocopherol, Hexapeptide-11, Palmitoyl Tripeptide-1, Ananas Sativus Fruit Extract, Saccharomyces/Magnesium Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Silicon Ferment, Butylene Glycol, Glyceryl Acrylate/Acrylic Acid Copolymer, Glyceryl Caprylate, Sucrose Stearate, Lecithin, Polyglyceryl-10 Laurate, Xanthan Gum, Cetearyl Olivate, Sorbitan Olivate, Sodium Citrate, Carbomer, Citric Acid, Cetearyl Alcohol, Sodium Hydroxide, Lactobacillus Ferment, Leuconostoc/Radish Root Ferment Filtrate, Hydroxyacetophenone, CI 77491

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →