MOG 35-55 Peptide - MEVGWYRSPFSRVVHLYRNGK

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MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

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Description

About MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

The MOG 35-55 peptide is a well-characterized immunodominant peptide derived from myelin oligodendrocyte glycoprotein. The sequence MEVGWYRSPFSRVVHLYRNGK is widely used to induce experimental autoimmune encephalomyelitis (EAE) in mouse models, making it a standard tool for studying multiple sclerosis and CNS demyelination.

Due to its strong and reproducible activation of antigen-specific CD4+ T cells, MOG35-55 (CAS Nr. 163913-87-9) is commonly applied in neuroimmunology to investigate inflammatory signaling, immune cell infiltration, and disease progression in the central nervous system. Its consistent performance in EAE induction makes it a reliable reference peptide for preclinical autoimmune research.

The Mouse Myelin-oligodendrocyte glycoprotein Peptide is a high quality epitope peptide for stimulation of antigen-specific T cells in T cell assays such as ELISPOT, ICS, cytotoxicity or proliferation assays. The Myelin-oligodendrocyte glycoprotein Peptide, H-MEVGWYRSPFSRVVHLYRNGK-OH (Uniprot: Q61885 aa: 35-55 (aa: 63-83)) from JPT is produced under strict quality control and quality management.

MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK) - Specifications

Peptide sequence: H-MEVGWYRSPFSRVVHLYRNGK-OH

Amount: 1 mg

Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)

Delivery Format: Freeze-dried in plastic vial

Application(s):

Condition(s)/Topic(s):

Standard Delivery Time: 2-5 days

CAS: 163913-87-9Peptide Name: Myelin Oligodendrocyte Glycoprotein Peptide 35-55, Mouse

Your Custom or Scrambled Antigen Peptide!

Do you need a scrambled version of this antigen peptide?We can produce scrambled versions for all our antigen peptides and other peptide sequences. These scrambled peptide versions are cross-checked against the Uniprot database to ensure that the scrambled sequence does not correspond to any natural sequence. Have a look at Scrambled Antigen Peptides!

Are you interested in other antigen peptides?Choose sequence, amount and purity. We will assist you along the way: Custom Peptide Synthesis

Applications of MOG 35-55 in Autoimmune Research

Induction of Experimental Autoimmune Encephalomyelitis (EAE)

MOG 35-55 is widely used to induce EAE in mice, providing a robust and reproducible model for studying autoimmune-mediated demyelination. This model enables detailed analysis of immune mechanisms relevant to multiple sclerosis.

Antigen-Specific T-Cell Activation

The peptide is suitable for controlled stimulation of antigen-specific T cells and is commonly used in ELISPOT, intracellular cytokine staining (ICS), cytotoxicity, and proliferation assays. It supports detailed characterization of T-cell responses and cytokine profiles.

Investigation of CNS Inflammation and Demyelination

MOG 35-55 is applied to study inflammatory signaling, immune cell infiltration, and myelin damage within the central nervous system. It provides a consistent experimental framework for evaluating disease mechanisms and therapeutic strategies.

Do you need a scrambled version of this antigen peptide? We can produce scrambled versions for all our antigen peptides and other peptide sequences. These scrambled peptide versions are cross-checked against the Uniprot database to ensure that the scrambled sequence does not correspond to any natural sequence. Have a look at Scrambled Antigen Peptides!

Are you interested in other antigen peptides?

Choose sequence, amount and purity. We will assist you along the way: Custom Peptide Synthesis

Why Choose JPT Antigen Peptides

Consistent peptide quality for reproducible immune assays

Manufactured in Germany under strict quality control

Optimized synthesis to minimize contaminants and side products

Freeze-dried format for stability and convenient handling

Scalable from small research quantities to bulk production

Compatible with PepMix peptide pool formats

References

References for MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

References:Read References with Antigen Peptides

Documentation

Documentation for MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

Protocol_PepMix.pdf

MOG-35-55-Mouse-Peptide-MEVGWYRSPFSRVVHLYRNGK-2.pdf

Properties

Properties of MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

Antigen Peptides

Freeze-dried in plastic vial

Mouse

Myelin-oligodendrocyte glycoprotein

Trial Grade: each peptide purified to > 90% (HPLC/MS)

Further Information to MOG (35-55), Mouse Peptide (MEVGWYRSPFSRVVHLYRNGK)

Values

H-MEVGWYRSPFSRVVHLYRNGK-OH