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Minimalist Multi-Peptides 10% Versus Dear, Klairs Freshly Juiced Vitamin Drop

Minimalist Multi-Peptides 10% Versus Dear, Klairs Freshly Juiced Vitamin Drop This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. This brightening serum is formu

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Minimalist Multi-Peptides 10% Versus Dear, Klairs Freshly Juiced Vitamin Drop

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

This brightening serum is formulated around Ascorbic Acid and Centella Asiatica Extract to brighten dull-looking skin and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butylene Glycol

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Acetyl Glutamine

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-9

Sh-Polypeptide-11

Pentylene Glycol

Bacillus/Folic Acid Ferment Filtrate Extract

Sodium Hyaluronate

Lecithin

Caprylyl Glycol

Carbomer

Polysorbate 20

Pullulan

Hydroxyethylcellulose

Xanthan Gum

PEG/PPG-17/6 Copolymer

Sclerotium Gum

Phenoxyethanol

Ethylhexylglycerin

Trisodium Ethylenediamine Disuccinate

Water, Glycerin, Butylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Pentylene Glycol, Bacillus/Folic Acid Ferment Filtrate Extract, Sodium Hyaluronate, Lecithin, Caprylyl Glycol, Carbomer, Polysorbate 20, Pullulan, Hydroxyethylcellulose, Xanthan Gum, PEG/PPG-17/6 Copolymer, Sclerotium Gum, Phenoxyethanol, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate

Propylene Glycol

Ascorbic Acid

Citrus Junos Fruit Extract

Centella Asiatica Extract

Polysorbate 60

Illicium Verum Fruit Extract

Chaenomeles Sinensis Fruit Extract

Paeonia Suffruticosa Root Extract

Brassica Oleracea Italica Extract

Nelumbium Speciosum Flower Extract

Citrus Paradisi Fruit Extract

Scutellaria Baicalensis Root Extract

Citrus Aurantium Dulcis Oil

1,2-Hexanediol

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Isohexadecane

Disodium EDTA

Lavandula Angustifolia Oil

Camellia Sinensis Callus Culture Extract

Polysorbate 80

Disodium Phosphate

Sorbitan Oleate

Chrysanthellum Indicum Extract

Asarum Sieboldii Root Extract

Quercus Mongolica Leaf Extract

Persicaria Hydropiper Extract

Larix Europaea Wood Extract

Magnolia Obovata Bark Extract

Rheum Palmatum Root Extract

Corydalis Turtschaninovii Root Extract

Coptis Chinensis Root Extract

Sodium Phosphate

Lysine Hcl

Sodium Ascorbyl Phosphate

Acetyl Methionine

Theanine

Proline

Bacillus/Folic Acid/Soybean Ferment Extract

Limonene

Water, Propylene Glycol, Ascorbic Acid, Hydroxyethylcellulose, Citrus Junos Fruit Extract, Centella Asiatica Extract, Polysorbate 60, Illicium Verum Fruit Extract, Chaenomeles Sinensis Fruit Extract, Paeonia Suffruticosa Root Extract, Brassica Oleracea Italica Extract, Nelumbium Speciosum Flower Extract, Citrus Paradisi Fruit Extract, Scutellaria Baicalensis Root Extract, Butylene Glycol, Glycerin, Citrus Aurantium Dulcis Oil, 1,2-Hexanediol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Disodium EDTA, Lavandula Angustifolia Oil, Camellia Sinensis Callus Culture Extract, Polysorbate 80, Disodium Phosphate, Sorbitan Oleate, Chrysanthellum Indicum Extract, Asarum Sieboldii Root Extract, Quercus Mongolica Leaf Extract, Persicaria Hydropiper Extract, Larix Europaea Wood Extract, Magnolia Obovata Bark Extract, Rheum Palmatum Root Extract, Corydalis Turtschaninovii Root Extract, Coptis Chinensis Root Extract, Sodium Phosphate, Lysine Hcl, Sodium Ascorbyl Phosphate, Acetyl Methionine, Theanine, Proline, Lecithin, Acetyl Glutamine, Bacillus/Folic Acid/Soybean Ferment Extract, Sodium Hyaluronate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Caprylyl Glycol, Limonene

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

We don't have a description for Acetyl Glutamine yet.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.

In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.

Studies find EGF help with:

In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

This peptide has similar properties to Sh-Oligopeptide-1.

There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.

Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.

Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.

It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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