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Medik8 Crystal Retinal 10 Versus The Ordinary Niacinamide 10% + Zinc 1%

Medik8 Crystal Retinal 10 Versus The Ordinary Niacinamide 10% + Zinc 1% This anti-aging serum is formulated around Retinal and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. This oil-control serum is formulated around Niacina

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Medik8 Crystal Retinal 10 Versus The Ordinary Niacinamide 10% + Zinc 1%

This anti-aging serum is formulated around Retinal and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture.

This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Caprylic/Capric Triglyceride

Glycerin

Isododecane

Cetearyl Olivate

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Cetearyl Alcohol

PPG-12/Smdi Copolymer

Sorbitan Olivate

Tocopheryl Acetate

Titanium Dioxide

Eclipta Prostrata Extract

Cyclodextrin

Squalane

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Phenoxyethanol

Melia Azadirachta Leaf Extract

Hydroxypropyl Methylcellulose

Sodium Hyaluronate

Tetrahexyldecyl Ascorbate

Rubus Chamaemorus Seed Oil

Alumina

Isostearic Acid

Lecithin

Polyglyceryl-3 Polyricinoleate

Polyhydroxystearic Acid

Stearic Acid

Pentylene Glycol

Retinal

Moringa Oleifera Seed Oil

Sodium Polyaspartate

Climbazole

Disodium EDTA

Lonicera Japonica Flower Extract

Lonicera Caprifolium Flower Extract

Daucus Carota Sativa Seed Oil

Ethylhexylglycerin

3-O-Ethyl Ascorbic Acid

Dipteryx Odorata Bean Extract

Hydroxyacetophenone

Polysorbate 60

Sorbitan Isostearate

Vanilla Planifolia Fruit Extract

Decylene Glycol

1,2-Hexanediol

BHT

Coumarin

Water, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Titanium Dioxide, Eclipta Prostrata Extract, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Melia Azadirachta Leaf Extract, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Pentylene Glycol, Retinal, Moringa Oleifera Seed Oil, Sodium Polyaspartate, Climbazole, Disodium EDTA, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Daucus Carota Sativa Seed Oil, Ethylhexylglycerin, 3-O-Ethyl Ascorbic Acid, Dipteryx Odorata Bean Extract, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Decylene Glycol, 1,2-Hexanediol, BHT, Coumarin

Niacinamide 10%

Zinc PCA 1%

Dimethyl Isosorbide

Tamarindus Indica Seed Gum

Xanthan Gum

Isoceteth-20

Ethoxydiglycol

Chlorphenesin

Water, Niacinamide 10%, Pentylene Glycol, Zinc PCA 1%, Dimethyl Isosorbide, Tamarindus Indica Seed Gum, Xanthan Gum, Isoceteth-20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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