Markus Muttenthaler

Trends in peptide drug discovery

M Muttenthaler, GF King, DJ Adams, PF Alewood

Nature reviews Drug discovery 20 (4), 309-325, 2021

23032021Discovery, synthesis and development of structure-activity relationships of Conotoxins

KB Akondi, M Muttenthaler, S Dutertre, Q Kaas, DJ Craik, RJ Lewis, ...

Chemical reviews 114 (11), 5815, 2014

3802014Conotoxins: chemistry and biology

AH Jin, M Muttenthaler, S Dutertre, SWA Himaya, Q Kaas, DJ Craik, ...

Chemical reviews 119 (21), 11510-11549, 2019

3002019Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

J Koehbach, M O’Brien, M Muttenthaler, M Miazzo, M Akcan, AG Elliott, ...

Proceedings of the National Academy of Sciences 110 (52), 21183-21188, 2013

1882013Selenopeptide chemistry

M Muttenthaler, PF Alewood

Journal of peptide science: an official publication of the European Peptide …, 2008

1722008Mucosal biofilms are an endoscopic feature of irritable bowel syndrome and ulcerative colitis

M Baumgartner, M Lang, H Holley, D Crepaz, B Hausmann, P Pjevac, ...

Gastroenterology 161 (4), 1245-1256. e20, 2021

1712021Modulating oxytocin activity and plasma stability by disulfide bond engineering

M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ...

Journal of medicinal chemistry 53 (24), 8585-8596, 2010

1572010Solving the α-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists

M Muttenthaler, ST Nevin, AA Grishin, ST Ngo, PT Choy, NL Daly, SH Hu, ...

Journal of the American Chemical Society 132 (10), 3514-3522, 2010

1522010Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ...

Nature communications 5 (1), 3165, 2014

1512014Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

C W. Gruber, M Muttenthaler, M Freissmuth

Current pharmaceutical design 16 (28), 3071-3088, 2010

1342010On the utility of chemical strategies to improve peptide gut stability

T Kremsmayr, A Aljnabi, JB Blanco-Canosa, HNT Tran, NB Emidio, ...

Journal of Medicinal Chemistry 65 (8), 6191, 2022

1262022Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides

S Dutertre, D Croker, NL Daly, A Andersson, M Muttenthaler, ...

Journal of Biological Chemistry 283 (11), 7100-7108, 2008

1132008α-Conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of α3β4 nicotinic acetylcholine receptors

AA Grishin, CIA Wang, M Muttenthaler, PF Alewood, RJ Lewis, DJ Adams

Journal of Biological Chemistry 285 (29), 22254-22263, 2010

952010Discovery of defense-and neuropeptides in social ants by genome-mining

CW Gruber, M Muttenthaler

PLoS One 7 (3), e32559, 2012

902012Insights into the molecular evolution of oxytocin receptor ligand binding

J Koehbach, T Stockner, C Bergmayr, M Muttenthaler, CW Gruber

Biochemical Society Transactions 41 (1), 197-204, 2013

852013Trefoil factor family: Unresolved questions and clinical perspectives

NB Emidio, W Hoffmann, SM Brierley, M Muttenthaler

Trends in biochemical sciences 44 (5), 387-390, 2019

802019Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure

M Busnelli, G Kleinau, M Muttenthaler, S Stoev, M Manning, L Bibic, ...

Journal of medicinal chemistry 59 (15), 7152-7166, 2016

792016The oxytocin receptor signalling system and breast cancer: a critical review

H Liu, CW Gruber, PF Alewood, A Möller, M Muttenthaler

Oncogene 39 (37), 5917-5932, 2020

772020Structure-activity studies on alpha-conotoxins

M Muttenthaler, K B. Akondi, P F. Alewood

Current pharmaceutical design 17 (38), 4226-4241, 2011

742011Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis

M Muttenthaler, F Albericio, PE Dawson

Nature Protocols 10 (7), 1067-1083, 2015

702015