Educational guide
MAP - KLAL - PN159 Peptide | 1 mg
MAP - KLAL - PN159 Peptide US$552.50 Excluding tax and shipping fees In stock Description About MAP - KLAL - PN159 Peptide MAP - KLAL - PN159 is an amphiphilic cell penetrating peptide (CPP) that can be used as a cargo delivery system across cell membranes and
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MAP - KLAL - PN159 Peptide
US$552.50
Excluding tax and shipping fees
In stock
Description
About MAP - KLAL - PN159 Peptide
MAP - KLAL - PN159 is an amphiphilic cell penetrating peptide (CPP) that can be used as a cargo delivery system across cell membranes and to study intracellular processes. This lysine-rich peptide is able to translocate through the cell membrane and facilitate the delivery of various cargoes such as proteins, peptides, antibodies, and liposomes. In addition, PN159 peptide was found to be able to modulate tight junctions in intestinal epithelial and blood–brain barrier models. It forms an a-helix and can change its secondary structure to a beta-sheet upon binding to the cell membrane. Described by Oehlke et al. 1998.
MAP - KLAL - PN159 Peptide - Specifications
Peptide sequence: H-KLALKLALKALKAALKLA-NH2
Amount: 1 mg
Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)
Counterion: TFA
Delivery Format: Freeze-dried in plastic vial
MW (average): 1876.48
Application(s): Drug delivery
Condition(s)/Topic(s): Cancer, Gene therapy
Standard Delivery Time: 2-5 days
JPT’s Cell Penetrating Peptides – CPPs
Cell Penetrating Peptides (CPPs) are capable of crossing cellular membranes, facilitating the delivery of various therapeutic and experimental cargoes, such as bioactive molecules, into cells. Their ability to transport molecules that otherwise cannot penetrate cell membranes, such as proteins, peptides, and even large nucleic acids like plasmid DNA or RNA, makes them indispensable for both fundamental research and clinical applications. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.
All peptides are made in Germany
Bulk orders or custom peptide synthesis upon request
Provision of freeze-dried aliquots for enhanced stability
Proven track record
Need the conjugated or modified peptide? Contact us!
References
References for MAP - KLAL - PN159 Peptide
References:Read References with Specialty PeptidesTestimonial:"Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle."Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands
Testimonial:Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands
Documentation
Documentation for MAP - KLAL - PN159 Peptide
MAP-KLAL-PN159-Peptide.pdf
Properties
Properties of MAP - KLAL - PN159 Peptide
1 mg
Drug delivery
Cell-Penetrating Peptides
Cancer, Gene therapy
Freeze-dried in plastic vial
Artificial
CPP
Trial Grade: each peptide purified to > 90% (HPLC/MS)
No
Further Information to MAP - KLAL - PN159 Peptide
Values
H-KLALKLALKALKAALKLA-NH2
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