Maleimido-GG-TAT(47-57) Peptide for membrane translocation

Maleimido-GG-TAT(47-57)

US$534.30

Excluding tax and shipping fees

In stock

Description

About Maleimido-GG-TAT(47-57)

Maleimido-GG-TAT(47-57) is a maleimido-functionalized TAT (47-57) peptide. It is a cationic cell penetrating peptide (CPP) that can be used as a cargo delivery system across cell membranes and to study intracellular processes. TAT (47-57) is a fragment of the HIV transactivator protein (TAT) protein transduction domain (PTD), here functionalized with a maleimido residue. This arginine-rich TAT peptide is able to translocate through the cell membrane and facilitate the delivery of various cargoes such as proteins, peptides, antibodies, and liposomes.

Maleimido-GG-TAT(47-57) - Specifications

Peptide sequence: MalPro-GGYGRKKRRQRRR-NH2

Amount: 1 mg

Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)

Counterion: TFA

Delivery Format: Freeze-dried in plastic vial

MW (average): 1824.09

Application(s): Drug delivery

Condition(s)/Topic(s): Cancer, Gene therapy

Standard Delivery Time: 2-5 days

JPT’s Cell Penetrating Peptides – CPPs

Cell Penetrating Peptides (CPPs) are capable of crossing cellular membranes, facilitating the delivery of various therapeutic and experimental cargoes, such as bioactive molecules, into cells. Their ability to transport molecules that otherwise cannot penetrate cell membranes, such as proteins, peptides, and even large nucleic acids like plasmid DNA or RNA, makes them indispensable for both fundamental research and clinical applications. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.

All peptides are made in Germany

Bulk orders or custom peptide synthesis upon request

Provision of freeze-dried aliquots for enhanced stability

Proven track record

Need the conjugated or modified peptide? Contact us!

References

References for Maleimido-GG-TAT(47-57)

References:Read References with Specialty PeptidesTestimonial:"Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle."Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

Testimonial:Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

Documentation

Documentation for Maleimido-GG-TAT(47-57)

Maleimido-GG-TAT47-57.pdf

Properties

Properties of Maleimido-GG-TAT(47-57)

1 mg

Drug delivery

Cell-Penetrating Peptides

Cancer, Gene therapy

Freeze-dried in plastic vial

Human immunodeficiency virus (HIV)

CPP

Trial Grade: each peptide purified to > 90% (HPLC/MS)

No

Further Information to Maleimido-GG-TAT(47-57)

Values

MalPro-GGYGRKKRRQRRR-NH2

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