Educational guide
Larazotide Acetate (AT-1001) — The Complete History
The Legacy A New Era Begins Today, larazotide remains the most advanced non-dietary treatment for celiac disease in clinical ... Key Moment Today, larazotide remains the most advanced non-dietary treatment for celiac disease in clinical development. Today, lar
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The Legacy
A New Era Begins
Today, larazotide remains the most advanced non-dietary treatment for celiac disease in clinical ...
Key Moment
Today, larazotide remains the most advanced non-dietary treatment for celiac disease in clinical development.
Today, larazotide remains the most advanced non-dietary treatment for celiac disease in clinical development. No drug has ever been approved specifically for celiac disease — patients can only avoid gluten, which is nearly impossible to do perfectly. Larazotide's approach of strengthening the gut barrier represents a fundamentally new strategy. Even if it doesn't eliminate the need for a gluten-free diet, it could protect patients from the damage caused by accidental gluten exposure. Fasano's journey from studying cholera in Italy to developing a celiac treatment in America shows how discoveries in one disease can unlock solutions for another. The tight junction — once an obscure concept in cell biology — is now a major drug target.