Lancôme Genifique Advanced Youth Activating Eye Cream Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

Lancôme Genifique Advanced Youth Activating Eye Cream Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

This anti-aging eye moisturizer is formulated around Bifida Ferment Lysate and Ascorbyl Glucoside to soften the look of wrinkles and strengthen the skin barrier.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cyclohexasiloxane

Bifida Ferment Lysate

Glycerin

Propanediol

Alcohol Denat.

Polysilicone-11

Dimethicone

Polymethylsilsesquioxane

Di-C12-13 Alkyl Malate

Ammonium Polyacryloyldimethyl Taurate

CI 77891

Ascorbyl Glucoside

Mica

Lactobacillus Ferment

Hydrogenated Vegetable Oil

Sodium Hyaluronate

Sodium Benzoate

Hydrolyzed Wheat Protein

Sodium

Sodium Dehydroacetate

Sodium Succinate

Phenoxyethanol

Adenosine

Yeast Extract

Ptfe

PEG-10 Dimethicone

Arginine

Triethanolamine

Chlorphenesin

Chlorhexidine Digluconate

Polygonum Fagopyrum Seed Extract

Silica

Salicyloyl Phytosphingosine

Chlorella Vulgaris Extract

Dimethiconol

Limonene

Pentylene Glycol

Synthetic Fluorphlogopite

Linalool

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Biosaccharide Gum-1

Caprylic/Capric Triglyceride

Carbomer

Boron Nitride

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Geraniol

Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone

Disodium EDTA

Ceteareth-20

Potassium Cetyl Phosphate

Citronellol

Methionine

Potassium Sorbate

Glycine

Parfum

Water, Cyclohexasiloxane, Bifida Ferment Lysate, Glycerin, Propanediol, Alcohol Denat., Polysilicone-11, Dimethicone, Polymethylsilsesquioxane, Di-C12-13 Alkyl Malate, Ammonium Polyacryloyldimethyl Taurate, CI 77891, Ascorbyl Glucoside, Mica, Lactobacillus Ferment, Hydrogenated Vegetable Oil, Sodium Hyaluronate, Sodium Benzoate, Hydrolyzed Wheat Protein, Sodium, Sodium Dehydroacetate, Sodium Succinate, Phenoxyethanol, Adenosine, Yeast Extract, Ptfe, PEG-10 Dimethicone, Arginine, Triethanolamine, Chlorphenesin, Chlorhexidine Digluconate, Polygonum Fagopyrum Seed Extract, Silica, Salicyloyl Phytosphingosine, Chlorella Vulgaris Extract, Dimethiconol, Limonene, Pentylene Glycol, Synthetic Fluorphlogopite, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Biosaccharide Gum-1, Caprylic/Capric Triglyceride, Carbomer, Boron Nitride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Geraniol, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Disodium EDTA, Ceteareth-20, Potassium Cetyl Phosphate, Citronellol, Methionine, Potassium Sorbate, Glycine, Parfum

Isohexadecane

Butylene Glycol

Bis-PEG-18 Methyl Ether Dimethyl Silane

Disteardimonium Hectorite

Isopropyl Isostearate

PPG-15 Stearyl Ether

Sucrose

Trehalose

Adansonia Digitata Seed Extract

Tripeptide-32

Faex Extract

Algae Extract

Sodium Rna

Hydrolyzed Algin

Caffeine

Hydroxyethyl Urea

Aminopropyl Ascorbyl Phosphate

Cucumis Sativus Fruit Extract

Anthemis Nobilis Flower Extract

Hordeum Vulgare Extract

Silybum Marianum Extract

Glycine Soja Seed Extract

Camelina Sativa Seed Oil

Sorbitol

Betula Alba Bark Extract

Scutellaria Baicalensis Root Extract

Morus Bombycis Root Extract

Poria Cocos Sclerotium Extract

Tocopheryl Acetate

Propylene Glycol Dicaprate

Sodium Polyaspartate

Hydrogenated Lecithin

Phytosphingosine

Ethylhexylglycerin

Isododecane

Helianthus Annuus Seed Extract

Polyethylene

Propylene Carbonate

Polyacrylate Crosspolymer-6

Lecithin

Glucose

Fructose

T-Butyl Alcohol

BHT

Hydroxyacetophenone

CI 77491

Water, Dimethicone, Bifida Ferment Lysate, Isohexadecane, Glycerin, Butylene Glycol, Bis-PEG-18 Methyl Ether Dimethyl Silane, PEG-10 Dimethicone, Disteardimonium Hectorite, Isopropyl Isostearate, PPG-15 Stearyl Ether, Sucrose, Trehalose, Adansonia Digitata Seed Extract, Tripeptide-32, Faex Extract, Sodium Hyaluronate, Lactobacillus Ferment, Algae Extract, Sodium Rna, Hydrolyzed Algin, Caffeine, Hydroxyethyl Urea, Aminopropyl Ascorbyl Phosphate, Cucumis Sativus Fruit Extract, Anthemis Nobilis Flower Extract, Hordeum Vulgare Extract, Silybum Marianum Extract, Glycine Soja Seed Extract, Camelina Sativa Seed Oil, Sorbitol, Betula Alba Bark Extract, Scutellaria Baicalensis Root Extract, Morus Bombycis Root Extract, Poria Cocos Sclerotium Extract, Tocopheryl Acetate, Propylene Glycol Dicaprate, Sodium Polyaspartate, Hydrogenated Lecithin, Phytosphingosine, Ethylhexylglycerin, Polysilicone-11, Isododecane, Helianthus Annuus Seed Extract, Polyethylene, Propylene Carbonate, Polyacrylate Crosspolymer-6, Lecithin, Glucose, Fructose, T-Butyl Alcohol, Disodium EDTA, BHT, Hydroxyacetophenone, Sodium Dehydroacetate, Potassium Sorbate, Phenoxyethanol, CI 77491

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bifida Ferment Lysate is a postbiotic ingredient made by fermenting Bifidobacterium to extract a nutrient-rich mix of peptides, amino acids, vitamins, organic acids, and polysaccharides.

These components are basically the building blocks that your skin already uses to stay hydrated, repair itself, and maintain its barrier. That's why this ingredient helps your skin hold onto moisture and stay resilient against irritation.

One in-vitro study found that this ingredient tells your skin cells to produce more of the proteins (filaggrin, loricrin, and involucrin) for building a strong and healthy barrier. This study also found this ingredient to be a solid antioxidant that helped neutralize damage against UV and pollution.

A study with people from 2010 found that sensitive, reactive skin using a cream with 10% of this ingredient for a month became noticeably less dry, less reactive, and harder to irritate compared to the group using a plain cream.

In short, this ingredient is a well-tolerated ingredient that can help with barrier repair, antioxidant protection, and calming reactive skin.

This ingredient is generally considered fungal acne (Malassezia) safe; Bifidobacterium is a bacterium, not a yeast or fungus.

The fungal acne concern with fermented ingredients mainly applies to yeast-derived ferments like Saccharomyces and Galactomyces, because those are in the same kingdom as Malassezia and could theoretically contain residual compounds that feed it.

Bifida is a completely different organism, so on its own it doesn't provide a food source for the Malassezia yeast that causes fungal acne.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

This ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.

As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:

A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.

One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.

Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.

Why is this so cool?

Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.

So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.

On top of all this, it also acts as a mild antimicrobial preservative booster.

Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.

Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.

Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.

Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.

Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.

Peg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.

According to the manufacturer, acidic formulations decrease the stability of this ingredient. It works best in neutral or near neutral formulations.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysilicone-11 is a film-forming silicone that creates a non-tacky and matte finish on the skin. It's commonly used to improve texture, absorb excess oil, and help active ingredients spread evenly.

Due to its "rubber-like" structure, it stays on the skin's surface instead of being absorbed. On the skin, it creates a flexible layer that enhances wearability and stability.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Dehydroacetate is a synthetic preservative and sodium salt form of dehydroacetic acid. It stops bacteria, mold, and yeast from growing in your products at low concentrations.

Clinical testing found it to be non-irritating, non-sensitizing, and non-photosensitizing. It's also not significantly absorbed through skin.

There are a very small number of reported cases of contact dermatitis in cases linked to wound-care creams used over compromised skin (rather than skincare).

Overall, this is a well-studied and low-risk preservative just doing its job.

Typical concentrations run up to 0.6%, which is also the maximum amount permitted under both EU CosIng regulations and US FDA guidelines.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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