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La Roche-Posay Hyalu B5 Eyes Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

La Roche-Posay Hyalu B5 Eyes Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex This anti-aging eye moisturizer is formulated around Panthenol and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin. This barrier-repair eye

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

La Roche-Posay Hyalu B5 Eyes Cream Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

This anti-aging eye moisturizer is formulated around Panthenol and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Butyrospermum Parkii Butter

Dimethicone

Prunus Armeniaca Kernel Oil

Pentaerythrityl Tetraethylhexanoate

Panthenol

Silica

Isohexadecane

Zea Mays Starch

Propylene Glycol

Hydroxypropyl Tetrahydropyrantriol

Beeswax

Stearic Acid

Palmitic Acid

PEG-100 Stearate

Glyceryl Stearate

PEG-20 Stearate

Stearyl Alcohol

Tin Oxide

Bis-PEG-18 Methyl Ether Dimethyl Silane

Sorbitan Oleate

Dimethiconol

Sodium Hyaluronate

Arginine PCA

Serine

Myristic Acid

Alumina

Disodium EDTA

Isopropyl Titanium Triisostearate

Hydrolyzed Hyaluronic Acid

Hydrolyzed Linseed Extract

Citric Acid

Acetyl Dipeptide-1 Cetyl Ester

Toluene Sulfonic Acid

Polysorbate 80

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

BHT

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Sodium Benzoate

Phenoxyethanol

Benzoic Acid

CI 77491

CI 77492

CI 77499

CI 77891

Mica

Water, Glycerin, Butyrospermum Parkii Butter, Dimethicone, Prunus Armeniaca Kernel Oil, Pentaerythrityl Tetraethylhexanoate, Panthenol, Silica, Isohexadecane, Zea Mays Starch, Propylene Glycol, Hydroxypropyl Tetrahydropyrantriol, Beeswax, Stearic Acid, Palmitic Acid, PEG-100 Stearate, Glyceryl Stearate, PEG-20 Stearate, Stearyl Alcohol, Tin Oxide, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sorbitan Oleate, Dimethiconol, Sodium Hyaluronate, Arginine PCA, Serine, Myristic Acid, Alumina, Disodium EDTA, Isopropyl Titanium Triisostearate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Citric Acid, Acetyl Dipeptide-1 Cetyl Ester, Toluene Sulfonic Acid, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, BHT, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Benzoate, Phenoxyethanol, Benzoic Acid, CI 77491, CI 77492, CI 77499, CI 77891, Mica

Methyl Trimethicone

Bifida Ferment Lysate

Dimethicone/Vinyl Dimethicone Crosspolymer

Propanediol

Sucrose

Petrolatum

Polysorbate 40

Trehalose

Algae Extract

Morus Bombycis Root Extract

Scutellaria Baicalensis Root Extract

Lactobacillus Ferment

Triticum Vulgare Germ Extract

Betula Alba Bark Extract

Hydrolyzed Algin

Poria Cocos Sclerotium Extract

Jojoba Alcohol

Ethylhexylglycerin

Glycine Soja Seed Extract

Isopropyl Jojobate

Jojoba Esters

Faex Extract

Hydrogenated Lecithin

Hordeum Vulgare Extract

PEG/PPG-18/18 Dimethicone

Cholesterol

Anthemis Nobilis Flower Extract

Tocopheryl Acetate

Sodium Rna

Caffeine

Caprylyl Glycol

Phytosphingosine

Squalane

Potassium Sulfate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tripeptide-32

Butylene Glycol

Tromethamine

Methyl Trimethicone, Water, Bifida Ferment Lysate, Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Propanediol, Sucrose, Petrolatum, Polysorbate 40, Trehalose, Algae Extract, Morus Bombycis Root Extract, Scutellaria Baicalensis Root Extract, Lactobacillus Ferment, Triticum Vulgare Germ Extract, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Betula Alba Bark Extract, Hydrolyzed Algin, Poria Cocos Sclerotium Extract, Jojoba Alcohol, Ethylhexylglycerin, Glycine Soja Seed Extract, Isopropyl Jojobate, Jojoba Esters, Isohexadecane, Faex Extract, Hydrogenated Lecithin, Hordeum Vulgare Extract, PEG/PPG-18/18 Dimethicone, Cholesterol, Anthemis Nobilis Flower Extract, Tocopheryl Acetate, Sodium Rna, Caffeine, Polysorbate 80, Caprylyl Glycol, Phytosphingosine, Squalane, Potassium Sulfate, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tripeptide-32, Butylene Glycol, Tromethamine, Disodium EDTA, BHT, Phenoxyethanol, CI 77491, CI 77492, CI 77499

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is a synthetic polymer used to stabilize formulas and give products a "gel-cream" feel.

When applied, this ingredient mostly stays on the surface of skin. Safety reviews have found these polymers safe in cosmetics when made to proper quality standards. Testing also shows they’re unlikely to cause irritation or sensitization at normal use levels.

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.

Iron III oxides are classified as inorganic chemicals for coloring.

Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

CI 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.

Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 80 is a synthetic surfactant and emulsifier derived from sorbitol and oleic acid.

It reduces the surface tension between oil and water phases to help them stay mixed and stable in a formulation. In other words, it prevents your formulas from separating into an oily mess.

The CIR Expert Panel has evaluated the scientific data and found this ingredient to be safe, non-irritating, and non-sensitizing at concentrations up to 5% (it's even approved by the FDA as an OTC eye drop ingredient).

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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