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La Roche-Posay Cicaplast Baume B5+ Versus Nø Cosmetics All-In Barrier Cream

La Roche-Posay Cicaplast Baume B5+ Versus Nø Cosmetics All-In Barrier Cream This barrier-repair moisturizer is formulated around Panthenol and Centella Asiatica Leaf Extract to strengthen the skin barrier and calm redness. This barrier-repair moisturizer is fo

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

La Roche-Posay Cicaplast Baume B5+ Versus Nø Cosmetics All-In Barrier Cream

This barrier-repair moisturizer is formulated around Panthenol and Centella Asiatica Leaf Extract to strengthen the skin barrier and calm redness.

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Panthenol to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Hydrogenated Polyisobutene

Dimethicone

Glycerin

Butyrospermum Parkii Butter

Panthenol

Zea Mays Starch

Propanediol

Butylene Glycol

Cetyl PEG/PPG-10/1 Dimethicone

Trihydroxystearin

Centella Asiatica Leaf Extract

Polymnia Sonchifolia Root Juice

Zinc Gluconate

Madecassoside

Manganese Gluconate

Alpha-Glucan Oligosaccharide

Silica

Aluminum Hydroxide

Magnesium Sulfate

Mannose

Capryloyl Glycine

Caprylyl Glycol

Vitreoscilla Ferment

Citric Acid

Trisodium Ethylenediamine Disuccinate

Lactobacillus

Acetylated Glycol Stearate

Maltodextrin

Polyglyceryl-4 Isostearate

Tocopherol

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Titanium Dioxide

Water, Hydrogenated Polyisobutene, Dimethicone, Glycerin, Butyrospermum Parkii Butter, Panthenol, Zea Mays Starch, Propanediol, Butylene Glycol, Cetyl PEG/PPG-10/1 Dimethicone, Trihydroxystearin, Centella Asiatica Leaf Extract, Polymnia Sonchifolia Root Juice, Zinc Gluconate, Madecassoside, Manganese Gluconate, Alpha-Glucan Oligosaccharide, Silica, Aluminum Hydroxide, Magnesium Sulfate, Mannose, Capryloyl Glycine, Caprylyl Glycol, Vitreoscilla Ferment, Citric Acid, Trisodium Ethylenediamine Disuccinate, Lactobacillus, Acetylated Glycol Stearate, Maltodextrin, Polyglyceryl-4 Isostearate, Tocopherol, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Titanium Dioxide

Cetearyl Alcohol

Simmondsia Chinensis Seed Oil

Dicaprylyl Ether

Glyceryl Stearate

Prunus Armeniaca Kernel Oil

C13-15 Alkane

Pentylene Glycol

Cetearyl Olivate

Argania Spinosa Kernel Oil

Diglycerin

Ectoin

Ceramide EOP

Ceramide Ns

Ceramide NP

Ceramide As

Ceramide AP

Cholesterol

Hydrogenated Lecithin

Sucrose Distearate

Heterotheca Inuloides Flower Extract

Dipropylene Glycol

Sorbitan Olivate

Sea Water

Laminaria Digitata Extract

Chlorella Vulgaris Extract

Saccharide Isomerate

Xanthan Gum

Hydroxyacetophenone

Phenoxyethanol

Ethylhexylglycerin

Lactic Acid

Water, Butyrospermum Parkii Butter, Panthenol, Cetearyl Alcohol, Simmondsia Chinensis Seed Oil, Dicaprylyl Ether, Glycerin, Glyceryl Stearate, Prunus Armeniaca Kernel Oil, C13-15 Alkane, Propanediol, Pentylene Glycol, Cetearyl Olivate, Argania Spinosa Kernel Oil, Diglycerin, Ectoin, Ceramide EOP, Ceramide Ns, Ceramide NP, Ceramide As, Ceramide AP, Cholesterol, Hydrogenated Lecithin, Sucrose Distearate, Heterotheca Inuloides Flower Extract, Dipropylene Glycol, Sorbitan Olivate, Sea Water, Laminaria Digitata Extract, Chlorella Vulgaris Extract, Saccharide Isomerate, Xanthan Gum, Hydroxyacetophenone, Phenoxyethanol, Ethylhexylglycerin, Lactic Acid, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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