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La Mer Genaissance de la Mer The Serum Essence Versus The Ordinary Niacinamide 10% + Zinc 1%

La Mer Genaissance de la Mer The Serum Essence Versus The Ordinary Niacinamide 10% + Zinc 1% This anti-aging serum is formulated around Palmitoyl Hexapeptide-12 and Acetyl Hexapeptide-8 to soften the look of wrinkles. This oil-control serum is formulated aroun

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

La Mer Genaissance de la Mer The Serum Essence Versus The Ordinary Niacinamide 10% + Zinc 1%

This anti-aging serum is formulated around Palmitoyl Hexapeptide-12 and Acetyl Hexapeptide-8 to soften the look of wrinkles.

This oil-control serum is formulated around Niacinamide and Zinc PCA to balance excess oil and refine the look of pores.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Algae Extract

Dimethicone

Isododecane

Polysilicone-11

Glycerin

Butylene Glycol

Caprylic/Capric Triglyceride

PEG-10 Dimethicone

Coco-Caprylate/Caprate

Sesamum Indicum Seed Oil

Medicago Sativa Seed Powder

Helianthus Annuus Seedcake

Prunus Amygdalus Dulcis Seed Meal

Eucalyptus Globulus Leaf Oil

Sodium Gluconate

Copper Gluconate

Calcium Gluconate

Magnesium Gluconate

Zinc Gluconate

Tocopheryl Succinate

Niacin

Sesamum Indicum Seed Powder

Water

Propanediol

Hypnea Musciformis Extract

Gelidiella Acerosa Extract

Prunus Amygdalus Dulcis Seed Extract

Whey Protein

Caffeine

Acetyl Glucosamine

Pisum Sativum Extract

Helichrysum Arenarium Extract

Polygonum Cuspidatum Root Extract

Bambusa Vulgaris Extract

Centaurium Erythraea Extract

Bis-PEG-18 Methyl Ether Dimethyl Silane

Laminaria Digitata Extract

Citrus Aurantifolia Peel Extract

Coffea Arabica Seed Extract

Rosmarinus Officinalis Leaf Extract

Triticum Vulgare Germ Extract

Rubus Idaeus Leaf Extract

Corallina Officinalis Extract

Sucrose

Limnanthes Alba Seed Oil

Sigesbeckia Orientalis Extract

Crithmum Maritimum Extract

Glycine Soja Seed Extract

Jania Rubens Extract

PEG-8

Hordeum Vulgare Extract

Molasses Extract

Chlorella Vulgaris Extract

Tocopheryl Acetate

Laminaria Saccharina Extract

Micrococcus Lysate

Saccharomyces Lysate Extract

Caprylic/Capric/Myristic/Stearic Triglyceride

Palmaria Palmata Extract

Palmitoyl Hexapeptide-12

Polyglyceryl-10 Laurate

Hydrolyzed Wheat Protein

Polysorbate 20

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Sodium PCA

Urea

Hydrogenated Polyisobutene

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Glyceryl Polymethacrylate

Sodium Hyaluronate

Glycosaminoglycans

Parfum

Isohexadecane

Pentylene Glycol

Tetrahexyldecyl Ascorbate

Tetraacetylphytosphingosine

Dipalmitoyl Hydroxyproline

Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

Squalane

Hydrogenated Vegetable Oil

Ruby Powder

Acetyl Hexapeptide-8

Hydrolyzed Rice Extract

Tourmaline

Hydrolyzed Algin

Potassium Sorbate

Gold

Glucosamine Hcl

Caprylyl Glycol

Yeast Polysaccharides

Polysorbate 80

Trehalose

Polyquaternium-51

Hexylene Glycol

Faex Extract

Cholesterol

Zea Mays Kernel Extract

Glycyrrhetinic Acid

Hydroxypropyl Cyclodextrin

Lecithin

Maltodextrin

Alcohol Denat.

Xanthan Gum

Polymethylsilsesquioxane

Trimethylsiloxysilicate

Disodium EDTA

BHT

Phenoxyethanol

Chlorphenesin

Hydroxycitronellal

Citronellol

Geraniol

Linalool

Limonene

Caramel

CI 14700

Algae Extract, Dimethicone, Isododecane, Polysilicone-11, Glycerin, Butylene Glycol, Caprylic/Capric Triglyceride, PEG-10 Dimethicone, Coco-Caprylate/Caprate, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Water, Propanediol, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Prunus Amygdalus Dulcis Seed Extract, Whey Protein, Caffeine, Acetyl Glucosamine, Pisum Sativum Extract, Helichrysum Arenarium Extract, Polygonum Cuspidatum Root Extract, Bambusa Vulgaris Extract, Centaurium Erythraea Extract, Bis-PEG-18 Methyl Ether Dimethyl Silane, Laminaria Digitata Extract, Citrus Aurantifolia Peel Extract, Coffea Arabica Seed Extract, Rosmarinus Officinalis Leaf Extract, Triticum Vulgare Germ Extract, Rubus Idaeus Leaf Extract, Corallina Officinalis Extract, Sucrose, Limnanthes Alba Seed Oil, Sigesbeckia Orientalis Extract, Crithmum Maritimum Extract, Glycine Soja Seed Extract, Jania Rubens Extract, PEG-8, Hordeum Vulgare Extract, Molasses Extract, Chlorella Vulgaris Extract, Tocopheryl Acetate, Laminaria Saccharina Extract, Micrococcus Lysate, Saccharomyces Lysate Extract, Caprylic/Capric/Myristic/Stearic Triglyceride, Palmaria Palmata Extract, Palmitoyl Hexapeptide-12, Polyglyceryl-10 Laurate, Hydrolyzed Wheat Protein, Polysorbate 20, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium PCA, Urea, Hydrogenated Polyisobutene, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Glyceryl Polymethacrylate, Sodium Hyaluronate, Glycosaminoglycans, Parfum, Isohexadecane, Pentylene Glycol, Tetrahexyldecyl Ascorbate, Tetraacetylphytosphingosine, Dipalmitoyl Hydroxyproline, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Squalane, Hydrogenated Vegetable Oil, Ruby Powder, Acetyl Hexapeptide-8, Hydrolyzed Rice Extract, Tourmaline, Hydrolyzed Algin, Potassium Sorbate, Gold, Glucosamine Hcl, Caprylyl Glycol, Yeast Polysaccharides, Polysorbate 80, Trehalose, Polyquaternium-51, Hexylene Glycol, Faex Extract, Cholesterol, Zea Mays Kernel Extract, Glycyrrhetinic Acid, Hydroxypropyl Cyclodextrin, Lecithin, Maltodextrin, Alcohol Denat., Xanthan Gum, Polymethylsilsesquioxane, Trimethylsiloxysilicate, Disodium EDTA, BHT, Phenoxyethanol, Chlorphenesin, Hydroxycitronellal, Citronellol, Geraniol, Linalool, Limonene, Caramel, CI 14700

Niacinamide 10%

Zinc PCA 1%

Dimethyl Isosorbide

Tamarindus Indica Seed Gum

Isoceteth-20

Ethoxydiglycol

Water, Niacinamide 10%, Pentylene Glycol, Zinc PCA 1%, Dimethyl Isosorbide, Tamarindus Indica Seed Gum, Xanthan Gum, Isoceteth-20, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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