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L1-6 (PLILLRLLR) Peptide for membrane translocation

L1-6 (PLILLRLLR) US$187.20 Excluding tax and shipping fees In stock Description About L1-6 (PLILLRLLR) L1-6 (PLILLRLLR) is a well-characterized cell penetrating or cell-permeable peptide that can be conjugated to nucleic acids and other macromolecules. Describ

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

L1-6 (PLILLRLLR)

US$187.20

Excluding tax and shipping fees

In stock

Description

About L1-6 (PLILLRLLR)

L1-6 (PLILLRLLR) is a well-characterized cell penetrating or cell-permeable peptide that can be conjugated to nucleic acids and other macromolecules. Described by Schmidt et al. 2017.

L1-6 (PLILLRLLR) - Specifications

Peptide sequence: H-PLILLRLLR-NH2

Amount: 1 mg

Purity: Trial Grade: each peptide purified to > 90% (HPLC/MS)

Counterion: TFA

Delivery Format: Freeze-dried in plastic vial

MW (average): 1105.49

Application(s): Drug delivery

Condition(s)/Topic(s):

Standard Delivery Time: 2-5 days

JPT’s Cell Penetrating Peptides – CPPs

Cell Penetrating Peptides (CPPs) are capable of crossing cellular membranes, facilitating the delivery of various therapeutic and experimental cargoes, such as bioactive molecules, into cells. Their ability to transport molecules that otherwise cannot penetrate cell membranes, such as proteins, peptides, and even large nucleic acids like plasmid DNA or RNA, makes them indispensable for both fundamental research and clinical applications. JPT Peptide Technologies has substantial, long-standing expertise in providing peptides in all formats, scales and modifications to the global scientific community. All our catalog peptides are provided with HPLC-MS analyses to confirm the identity and demonstrate the high quality of our peptides.

All peptides are made in Germany

Bulk orders or custom peptide synthesis upon request

Provision of freeze-dried aliquots for enhanced stability

Proven track record

Need the conjugated or modified peptide? Contact us!

References

References for L1-6 (PLILLRLLR)

References:Read References with Specialty PeptidesTestimonial:"Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle."Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

Testimonial:Our group focuses on the in vitro study of risk factors in Alzheimer’s disease and, as we experienced that the in-house expression and production of the amyloid beta peptide is notoriously difficult, we are continuously dependent on a high quality supply of a large variety of these peptides from commercial source.We started our collaboration with JPT with their request to test a range of their peptides for the ability to produce toxic oligomers and fibrillar networks and were impressed by the rapid supply of a very wide range of high purity peptides with excellent fibril forming properties and toxicity profiles. JPT has shown real valuable know-how and experience in the field of peptide synthesis by their ability to generate high quality preparations of amyloid beta peptide variants which are known for their difficulty to handle.Kerensa Broersen, Assistant Prof., Nanobiophysics Group, University of Twente, Enschede, The Netherlands

Documentation

Documentation for L1-6 (PLILLRLLR)

L1-6-PLILLRLLR.pdf

Properties

Properties of L1-6 (PLILLRLLR)

1 mg

Drug delivery

Cell-Penetrating Peptides

Freeze-dried in plastic vial

Artificial

CPP

Trial Grade: each peptide purified to > 90% (HPLC/MS)

No

Further Information to L1-6 (PLILLRLLR)

Values

H-PLILLRLLR-NH2

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Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

Research context

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Relevance of Claudin-6 in HBV Research

Claudin-6 is a significant protein in the context of HBV infection, acting as a key player in the virus's ability to enter and infect hepatocytes. Research into Claudin-6's role in HBV pathology can provide crucial insights into viral mechanisms and potential therapeutic targets. Our PepMix™ Human (Claudin-6) peptide is engineered to facilitate cutting-edge research into these mechanisms, allowing scientists to explore Claudin-6's interaction with HBV proteins. By using this peptide, researchers can delve into the molecular details of HBV infection and evaluate potential interventions targeting Claudin-6.

Source: jpt.com ↗

Disclaimers on Testagen Use for Hormonal and Immune Research

Testagen is a short peptide designed for research purposes only. It has not been approved by the FDA for human use. Most data on Testagen comes from in vitro specific interaction studies and clinical research in Russia. Because it acts through epigenetic regulation and gene expression, proper administration, dosage, and storage are essential. Improper use may affect DNA expression or cellular differentiation. This product should not be used without medical advice, especially if you have hormone-related disorders. Results may vary depending on age, testosterone levels, current health status, and peptide source. Always check that your product has been tested for purity, interaction ability, and safety.

Source: muscleandbrawn.com ↗
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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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