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L'Oreal Triple Power Eye Treatment Versus Estée Lauder Advanced Night Repair Supercharged Eye Gel-Cream

L'Oreal Triple Power Eye Treatment Versus Estée Lauder Advanced Night Repair Supercharged Eye Gel-Cream This anti-aging eye moisturizer is formulated around Caffeine and Adenosine to soften the look of wrinkles. This barrier-repair eye moisturizer is formulate

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

L'Oreal Triple Power Eye Treatment Versus Estée Lauder Advanced Night Repair Supercharged Eye Gel-Cream

This anti-aging eye moisturizer is formulated around Caffeine and Adenosine to soften the look of wrinkles.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Silica

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Prunus Armeniaca Kernel Oil

Isohexadecane

Dimethicone/Vinyl Dimethicone Crosspolymer

Hydroxypropyl Tetrahydropyrantriol

Propylene Glycol

CI 77891

Phenoxyethanol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Chlorphenesin

Mica

Triethanolamine

Polysorbate 80

Caffeine

Ascorbyl Glucoside

Dimethiconol

Adenosine

Tocopherol

Hydrolyzed Hyaluronic Acid

Hydroxyethylpiperazine Ethane Sulfonic Acid

Disodium EDTA

Sorbitan Oleate

Tin Oxide

Water, Dimethicone, Glycerin, Silica, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Prunus Armeniaca Kernel Oil, Isohexadecane, Dimethicone/Vinyl Dimethicone Crosspolymer, Hydroxypropyl Tetrahydropyrantriol, Propylene Glycol, CI 77891, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Chlorphenesin, Mica, Triethanolamine, Polysorbate 80, Caffeine, Ascorbyl Glucoside, Dimethiconol, Adenosine, Tocopherol, Hydrolyzed Hyaluronic Acid, Hydroxyethylpiperazine Ethane Sulfonic Acid, Disodium EDTA, Sorbitan Oleate, Tin Oxide

Methyl Trimethicone

Bifida Ferment Lysate

Propanediol

Petrolatum

Sucrose

Butylene Glycol

Trehalose

Tripeptide-32

Adansonia Digitata Seed Extract

Lavandula Angustifolia Flower Extract

Sodium Hyaluronate

Lactobacillus Ferment

Tocopheryl Acetate

Faex Extract

Hypnea Musciformis Extract

Sodium Rna

Squalane

Anthemis Nobilis Flower Oil

Poria Cocos Sclerotium Extract

Citrullus Lanatus Fruit Extract

Lens Esculenta Fruit Extract

Pyrus Malus Fruit Extract

Ethylhexylglycerin

Sodium PCA

Phytosphingosine

Hydrolyzed Algin

Hordeum Distichon Extract

Jojoba Esters

Triticum Vulgare Germ Oil

Hydrogenated Lecithin

Lecithin

Jojoba Alcohol

Isopropyl Jojobate

PEG/PPG-18/18 Dimethicone

Tromethamine

Sodium Lactate

Polysorbate 40

Potassium Gluconate

BHT

Potassium Sorbate

Sodium Benzoate

CI 77491

CI 77492

Water, Dimethicone, Methyl Trimethicone, Bifida Ferment Lysate, Dimethicone/Vinyl Dimethicone Crosspolymer, Propanediol, Petrolatum, Sucrose, Glycerin, Butylene Glycol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Trehalose, Tripeptide-32, Adansonia Digitata Seed Extract, Lavandula Angustifolia Flower Extract, Sodium Hyaluronate, Lactobacillus Ferment, Tocopheryl Acetate, Faex Extract, Hypnea Musciformis Extract, Sodium Rna, Caffeine, Squalane, Anthemis Nobilis Flower Oil, Poria Cocos Sclerotium Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Ethylhexylglycerin, Sodium PCA, Phytosphingosine, Hydrolyzed Algin, Hordeum Distichon Extract, Jojoba Esters, Triticum Vulgare Germ Oil, Hydrogenated Lecithin, Lecithin, Isohexadecane, Jojoba Alcohol, Isopropyl Jojobate, PEG/PPG-18/18 Dimethicone, Polysorbate 80, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Sorbitan Oleate, Sodium Lactate, Polysorbate 40, Potassium Gluconate, Tocopherol, BHT, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, CI 77491, CI 77492

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is a synthetic polymer used to stabilize formulas and give products a "gel-cream" feel.

When applied, this ingredient mostly stays on the surface of skin. Safety reviews have found these polymers safe in cosmetics when made to proper quality standards. Testing also shows they’re unlikely to cause irritation or sensitization at normal use levels.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.

As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.

Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.

You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.

Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.

Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

This ingredient is a silicone elastomer that works as a texture enhancer, adds a silky slip, and also helps absorb excess oil.

Because it's a large macromolecule that's insoluble in water and chemically inert, it's not expected to penetrate or be absorbed into skin.

Human patch tests with a facial lotion containing 1% of this ingredient found no sensitization.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Polysorbate 80 is a synthetic surfactant and emulsifier derived from sorbitol and oleic acid.

It reduces the surface tension between oil and water phases to help them stay mixed and stable in a formulation. In other words, it prevents your formulas from separating into an oily mess.

The CIR Expert Panel has evaluated the scientific data and found this ingredient to be safe, non-irritating, and non-sensitizing at concentrations up to 5% (it's even approved by the FDA as an OTC eye drop ingredient).

Sorbitan Oleate is a PEG-free emulsifier made by esterifying sorbitol with oleic acid.

You'll likely see it paired with Polysorbate 80 to create the right emulsification balance.

Typical use levels in formulas range from 2-10%.

The CIR Expert Panel has concluded this ingredient to be safe as a cosmetic ingredient.

Since this ingredient is an ester of oleic acid, it may not be fungal acne safe. Oleic acid is a fatty acid that falls into the C11-24 range that Malassezia can metabolize.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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