Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

L'Oreal Age Perfect Cell Renewal Midnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

L'Oreal Age Perfect Cell Renewal Midnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum This night moisturizer is formulated around Saccharomyces/Xylinum/Black Tea Ferment and Capryloyl Salicylic Acid to calm irritat

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

L'Oreal Age Perfect Cell Renewal Midnight Cream Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

This night moisturizer is formulated around Saccharomyces/Xylinum/Black Tea Ferment and Capryloyl Salicylic Acid to calm irritation and control oil.

This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Hydrogenated Polyisobutene

Dimethicone

Butylene Glycol

Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate

Butyrospermum Parkii Butter

Limnanthes Alba Seed Oil

Stearyl Alcohol

C30-45 Alkyl Dimethicone

PEG-20 Stearate

Saccharomyces/Xylinum/Black Tea Ferment

Panthenol

Silica

Adenosine

Capryloyl Salicylic Acid

Hydroxyacetophenone

Hydroxypropyl Tetrahydropyrantriol

Neohesperidin Dihydrochalcone

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Potassium Hydroxide

Tetrasodium Glutamate Diacetate

Tocopherol

Octyldodecanol

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Ammonium Polyacryloyldimethyl Taurate

Caprylyl Glycol

Carbomer

Citric Acid

Glyceryl Stearate

PEG-100 Stearate

PEG-30 Dipolyhydroxystearate

Propylene Glycol

Trideceth-6

Alpha-Isomethyl Ionone

Benzyl Alcohol

Benzyl Salicylate

Citronellol

Geraniol

Hexyl Cinnamal

Hydroxycitronellal

Limonene

Linalool

CI 14700

CI 19140

Chlorphenesin

Potassium Sorbate

Sodium Benzoate

Parfum

Water, Glycerin, Hydrogenated Polyisobutene, Dimethicone, Butylene Glycol, Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate, Butyrospermum Parkii Butter, Limnanthes Alba Seed Oil, Stearyl Alcohol, C30-45 Alkyl Dimethicone, PEG-20 Stearate, Saccharomyces/Xylinum/Black Tea Ferment, Panthenol, Silica, Adenosine, Capryloyl Salicylic Acid, Hydroxyacetophenone, Hydroxypropyl Tetrahydropyrantriol, Neohesperidin Dihydrochalcone, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Potassium Hydroxide, Tetrasodium Glutamate Diacetate, Tocopherol, Octyldodecanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Carbomer, Citric Acid, Glyceryl Stearate, PEG-100 Stearate, PEG-30 Dipolyhydroxystearate, Propylene Glycol, Trideceth-6, Alpha-Isomethyl Ionone, Benzyl Alcohol, Benzyl Salicylate, Citronellol, Geraniol, Hexyl Cinnamal, Hydroxycitronellal, Limonene, Linalool, CI 14700, CI 19140, Chlorphenesin, Potassium Sorbate, Sodium Benzoate, Parfum

Bifida Ferment Lysate

PEG-8

Propanediol

Bis-PEG-18 Methyl Ether Dimethyl Silane

Methyl Gluceth-20

Glycereth-26

PEG-75

Adansonia Digitata Seed Extract

Tripeptide-32

Sodium Hyaluronate

Faex Extract

Lactobacillus Ferment

Cola Acuminata Seed Extract

Anthemis Nobilis Flower Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Sodium Rna

Bisabolol

Squalane

Oleth-3 Phosphate

Oleth-3

Oleth-5

Choleth-24

Hydrogenated Lecithin

Jojoba Wax PEG-120 Esters

Ceteth-24

Tocopheryl Acetate

Triethanolamine

Tetrasodium EDTA

BHT

Xanthan Gum

Disodium EDTA

Phenoxyethanol

Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Ci 14700, also known as Red No. 4, is a synthetic red dye derived from petroleum. It is water soluble.

CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.

Tartrazine is created from petroleum and is water-soluble.

Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →