Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

L'Occitane Immortelle Reset Overnight Reset Oil-In Serum Versus Estée Lauder Advanced Night Repair Overnight Treatment

L'Occitane Immortelle Reset Overnight Reset Oil-In Serum Versus Estée Lauder Advanced Night Repair Overnight Treatment This anti-aging serum is formulated around Adenosine to soften the look of wrinkles. This barrier-repair night moisturizer is formulated arou

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

L'Occitane Immortelle Reset Overnight Reset Oil-In Serum Versus Estée Lauder Advanced Night Repair Overnight Treatment

This anti-aging serum is formulated around Adenosine to soften the look of wrinkles.

This barrier-repair night moisturizer is formulated around Butyrospermum Parkii Butter and Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Isononyl Isononanoate

Butylene Glycol

Pentylene Glycol

Dextrin Palmitate/Ethylhexanoate

Limnanthes Alba Seed Oil

Helichrysum Italicum Flower Oil

Origanum Majorana Leaf Extract

Acmella Oleracea Extract

Helianthus Annuus Seed Oil

Adenosine

Phenoxyethanol

Carbomer

Maltodextrin

Sodium Hydroxide

Palmitic Acid

Disodium EDTA

Cellulose Gum

Amodimethicone

Tocopherol

Parfum

CI 75130

Water, Propanediol, Glycerin, Isononyl Isononanoate, Butylene Glycol, Pentylene Glycol, Dextrin Palmitate/Ethylhexanoate, Limnanthes Alba Seed Oil, Helichrysum Italicum Flower Oil, Origanum Majorana Leaf Extract, Acmella Oleracea Extract, Helianthus Annuus Seed Oil, Adenosine, Phenoxyethanol, Carbomer, Maltodextrin, Sodium Hydroxide, Palmitic Acid, Disodium EDTA, Cellulose Gum, Amodimethicone, Tocopherol, Parfum, CI 75130

Butyrospermum Parkii Butter

Theobroma Cacao Seed Butter

Coco-Caprylate/Caprate

Caprylic/Capric/Myristic/Stearic Triglyceride

Glyceryl Stearate

Cetyl Alcohol

C9-12 Alkane

Dimethicone

Cetearyl Alcohol

PEG-100 Stearate

Tripeptide-32

Sodium Hyaluronate

Sodium Polyglutamate

Succinic Acid

Artemia Extract

Squalane

Lactobacillus Ferment

Tocopheryl Acetate

Caffeine

Algae Extract

Lavandula Angustifolia Flower Extract

Hydrolyzed Rice Extract

Faex Extract

Hordeum Vulgare Extract

Anthemis Nobilis Flower Extract

Cucumis Sativus Fruit Extract

Helianthus Annuus Seed Extract

Sorbitol

Potassium Palmitoyl Hydrolyzed Wheat Protein

Propylene Glycol Dicaprate

Steareth-21

Dimethicone Crosspolymer-3

Steareth-2

Hexylene Glycol

Xanthan Gum

Caprylyl Glycol

Ethylhexylglycerin

Glucose

BHT

Sodium Dehydroacetate

Potassium Sorbate

CI 19140

CI 14700

Water, Butyrospermum Parkii Butter, Theobroma Cacao Seed Butter, Coco-Caprylate/Caprate, Caprylic/Capric/Myristic/Stearic Triglyceride, Butylene Glycol, Glyceryl Stearate, Cetyl Alcohol, Glycerin, C9-12 Alkane, Dimethicone, Cetearyl Alcohol, PEG-100 Stearate, Tripeptide-32, Sodium Hyaluronate, Sodium Polyglutamate, Succinic Acid, Artemia Extract, Squalane, Lactobacillus Ferment, Tocopheryl Acetate, Caffeine, Algae Extract, Lavandula Angustifolia Flower Extract, Hydrolyzed Rice Extract, Faex Extract, Hordeum Vulgare Extract, Anthemis Nobilis Flower Extract, Cucumis Sativus Fruit Extract, Helianthus Annuus Seed Extract, Sorbitol, Potassium Palmitoyl Hydrolyzed Wheat Protein, Propylene Glycol Dicaprate, Maltodextrin, Steareth-21, Dimethicone Crosspolymer-3, Steareth-2, Hexylene Glycol, Xanthan Gum, Caprylyl Glycol, Ethylhexylglycerin, Glucose, BHT, Disodium EDTA, Phenoxyethanol, Sodium Dehydroacetate, Potassium Sorbate, CI 19140, CI 14700

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Maltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.

This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).

Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.

Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →