Educational guide
Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum This oil-control serum is formulated around Niacinamide to balance excess oil and refine the look of pores. This barrier-
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Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
This oil-control serum is formulated around Niacinamide to balance excess oil and refine the look of pores.
This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Niacinamide
Glycerin
Propanediol
Methyl Gluceth-20
Hydroxyacetophenone
Sodium Hyaluronate
Caprylyl Glycol
Carbomer
Sodium Hydroxide
Water, Niacinamide, Glycerin, Propanediol, Methyl Gluceth-20, Hydroxyacetophenone, Sodium Hyaluronate, Caprylyl Glycol, Carbomer, Sodium Hydroxide
Bifida Ferment Lysate
PEG-8
Bis-PEG-18 Methyl Ether Dimethyl Silane
Glycereth-26
PEG-75
Butylene Glycol
Adansonia Digitata Seed Extract
Tripeptide-32
Faex Extract
Lactobacillus Ferment
Cola Acuminata Seed Extract
Anthemis Nobilis Flower Extract
Hydrolyzed Algin
Pantethine
Caffeine
Lecithin
Sodium Rna
Bisabolol
Squalane
Oleth-3 Phosphate
Oleth-3
Oleth-5
Choleth-24
Hydrogenated Lecithin
Jojoba Wax PEG-120 Esters
Ceteth-24
Tocopheryl Acetate
Triethanolamine
Tetrasodium EDTA
BHT
Xanthan Gum
Potassium Sorbate
Disodium EDTA
Phenoxyethanol
CI 14700
CI 19140
Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
It is created by combining polyethylene glycol with glucose.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!