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IT Cosmetics Confidence in a Cream Hydrating Moisturizer Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

IT Cosmetics Confidence in a Cream Hydrating Moisturizer Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Niacinamide to strengthen the skin barrier and hydrate skin.

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

IT Cosmetics Confidence in a Cream Hydrating Moisturizer Versus Estée Lauder Advanced Night Repair Eye Supercharged Complex

This barrier-repair moisturizer is formulated around Sodium Hyaluronate and Niacinamide to strengthen the skin barrier and hydrate skin.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Butylene Glycol

Cyclopentasiloxane

Glycerin

Butylene Glycol Dicaprylate/Dicaprate

Ethylhexyl Isononanoate

Hydrogenated Polyisobutene

Caprylic/Capric/Myristic/Stearic Triglyceride

Glyceryl Stearate

PEG-100 Stearate

Polyglyceryl-3 Methylglucose Distearate

Stearyl Behenate

Dimethicone

Pentaerythrityl Tetraethylhexanoate

Biosaccharide Gum-1

Dimethicone/Vinyl Dimethicone Crosspolymer

Cetearyl Alcohol

Palmitic Acid

Stearic Acid

Polyethylene

PEG/PPG-20/15 Dimethicone

Phenyl Methicone

Portulaca Oleracea Extract

Cocos Nucifera Oil

Aloe Barbadensis Leaf Extract

Butyrospermum Parkii Butter

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sodium Hyaluronate

Hydrogenated Lecithin

Polyquaternium-51

Niacinamide

Hydrolyzed Collagen

Camellia Sinensis Leaf Extract

Tocopheryl Acetate

Carbomer

PEG-150 Distearate

Ceramide AP

Glycosphingolipids

Glyceryl Polymethacrylate

Meadowfoam Estolide

Sorbitan Isostearate

Squalane

Palmitoyl Pentapeptide-4

Polysorbate 20

Steareth-20

N-Hydroxysuccinimide

Chrysin

Palmitoyl Tripeptide-1

Palmitoyl Tetrapeptide-7

Polysorbate 60

Aleuritic Acid

Yeast Extract

Glycoproteins

Betaine

Hydrogenated Polydecene

Ceramide NP

Allantoin

Colloidal Oatmeal

Retinyl Retinoate

Polylactic Acid

Canola Oil

Cholesteryl Nonanoate

Ascorbyl Tetraisopalmitate

Glycyrrhiza Glabra Root Extract

Chamomilla Recutita Flower Water

Curcuma Longa Root Extract

Leuconostoc/Radish Root Ferment Filtrate

Eruca Sativa Leaf Extract

Glyceryl Citrate/Lactate/Linoleate/Oleate

Ceteareth-20

Hydroxypropyl Bispalmitamide Mea

Glycine Soja Sterols

Melaleuca Alternifolia Leaf Oil

Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate

Santalum Album Oil

Chamomilla Recutita Flower Oil

Caprylhydroxamic Acid

Cetearyl Glucoside

Glucose

Stearyl Stearate

Tromethamine

Citric Acid

1,2-Hexanediol

Chlorhexidine Digluconate

Potassium Sorbate

Dipropylene Glycol

Lavandula Angustifolia Oil

Citrus Paradisi Peel Oil

Cymbopogon Citratus Leaf Oil

Pelargonium Graveolens Oil

Citrus Aurantium Dulcis Peel Oil

Pogostemon Cablin Leaf Oil

Citrus Aurantium Bergamia Fruit Oil

Ethylhexylglycerin

Caramel

Disodium EDTA

Phenoxyethanol

Caprylyl Glycol

Limonene

Linalool

Water, Butylene Glycol, Cyclopentasiloxane, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Ethylhexyl Isononanoate, Hydrogenated Polyisobutene, Caprylic/Capric/Myristic/Stearic Triglyceride, Glyceryl Stearate, PEG-100 Stearate, Polyglyceryl-3 Methylglucose Distearate, Stearyl Behenate, Dimethicone, Pentaerythrityl Tetraethylhexanoate, Biosaccharide Gum-1, Dimethicone/Vinyl Dimethicone Crosspolymer, Cetearyl Alcohol, Palmitic Acid, Stearic Acid, Polyethylene, PEG/PPG-20/15 Dimethicone, Phenyl Methicone, Portulaca Oleracea Extract, Cocos Nucifera Oil, Aloe Barbadensis Leaf Extract, Butyrospermum Parkii Butter, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Hyaluronate, Hydrogenated Lecithin, Polyquaternium-51, Niacinamide, Hydrolyzed Collagen, Camellia Sinensis Leaf Extract, Tocopheryl Acetate, Carbomer, PEG-150 Distearate, Ceramide AP, Glycosphingolipids, Glyceryl Polymethacrylate, Meadowfoam Estolide, Sorbitan Isostearate, Squalane, Palmitoyl Pentapeptide-4, Polysorbate 20, Steareth-20, N-Hydroxysuccinimide, Chrysin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Polysorbate 60, Aleuritic Acid, Yeast Extract, Glycoproteins, Betaine, Hydrogenated Polydecene, Ceramide NP, Allantoin, Colloidal Oatmeal, Retinyl Retinoate, Polylactic Acid, Canola Oil, Cholesteryl Nonanoate, Ascorbyl Tetraisopalmitate, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Water, Curcuma Longa Root Extract, Leuconostoc/Radish Root Ferment Filtrate, Eruca Sativa Leaf Extract, Glyceryl Citrate/Lactate/Linoleate/Oleate, Ceteareth-20, Hydroxypropyl Bispalmitamide Mea, Glycine Soja Sterols, Melaleuca Alternifolia Leaf Oil, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Santalum Album Oil, Chamomilla Recutita Flower Oil, Caprylhydroxamic Acid, Cetearyl Glucoside, Glucose, Stearyl Stearate, Tromethamine, Citric Acid, 1,2-Hexanediol, Chlorhexidine Digluconate, Potassium Sorbate, Dipropylene Glycol, Lavandula Angustifolia Oil, Citrus Paradisi Peel Oil, Cymbopogon Citratus Leaf Oil, Pelargonium Graveolens Oil, Citrus Aurantium Dulcis Peel Oil, Pogostemon Cablin Leaf Oil, Citrus Aurantium Bergamia Fruit Oil, Ethylhexylglycerin, Caramel, Disodium EDTA, Phenoxyethanol, Caprylyl Glycol, Limonene, Linalool

Methyl Trimethicone

Bifida Ferment Lysate

Propanediol

Sucrose

Petrolatum

Polysorbate 40

Trehalose

Algae Extract

Morus Bombycis Root Extract

Scutellaria Baicalensis Root Extract

Lactobacillus Ferment

Triticum Vulgare Germ Extract

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Betula Alba Bark Extract

Hydrolyzed Algin

Poria Cocos Sclerotium Extract

Jojoba Alcohol

Glycine Soja Seed Extract

Isopropyl Jojobate

Jojoba Esters

Isohexadecane

Faex Extract

Hordeum Vulgare Extract

PEG/PPG-18/18 Dimethicone

Cholesterol

Anthemis Nobilis Flower Extract

Sodium Rna

Caffeine

Polysorbate 80

Phytosphingosine

Potassium Sulfate

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tripeptide-32

BHT

CI 77491

CI 77492

CI 77499

Methyl Trimethicone, Water, Bifida Ferment Lysate, Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Propanediol, Sucrose, Petrolatum, Polysorbate 40, Trehalose, Algae Extract, Morus Bombycis Root Extract, Scutellaria Baicalensis Root Extract, Lactobacillus Ferment, Triticum Vulgare Germ Extract, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Betula Alba Bark Extract, Hydrolyzed Algin, Poria Cocos Sclerotium Extract, Jojoba Alcohol, Ethylhexylglycerin, Glycine Soja Seed Extract, Isopropyl Jojobate, Jojoba Esters, Isohexadecane, Faex Extract, Hydrogenated Lecithin, Hordeum Vulgare Extract, PEG/PPG-18/18 Dimethicone, Cholesterol, Anthemis Nobilis Flower Extract, Tocopheryl Acetate, Sodium Rna, Caffeine, Polysorbate 80, Caprylyl Glycol, Phytosphingosine, Squalane, Potassium Sulfate, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tripeptide-32, Butylene Glycol, Tromethamine, Disodium EDTA, BHT, Phenoxyethanol, CI 77491, CI 77492, CI 77499

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

This ingredient is a silicone elastomer that works as a texture enhancer, adds a silky slip, and also helps absorb excess oil.

Because it's a large macromolecule that's insoluble in water and chemically inert, it's not expected to penetrate or be absorbed into skin.

Human patch tests with a facial lotion containing 1% of this ingredient found no sensitization.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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