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innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus SKIN1004 Madagascar Centella Tone Brightening Boosting Toner

innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus SKIN1004 Madagascar Centella Tone Brightening Boosting Toner This anti-aging essence is formulated around Niacinamide and Copper Tripeptide-1 to soften the look of wrinkles and bright

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

innisfree Youth Enhancing Treatment Essence with Black Tea + Peptides Versus SKIN1004 Madagascar Centella Tone Brightening Boosting Toner

This anti-aging essence is formulated around Niacinamide and Copper Tripeptide-1 to soften the look of wrinkles and brighten dull-looking skin.

This brightening toner is formulated around Centella Asiatica Extract and Niacinamide to brighten dull-looking skin and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Camellia Sinensis Leaf Water 95%

Water

Propanediol

Glycerin

Niacinamide

1,2-Hexanediol

Camellia Sinensis Leaf Extract

Ethylhexylglycerin

Adenosine

Dextrin

Ectoin

Hyaluronic Acid

3-O-Ethyl Ascorbic Acid

Glutathione

Mannitol

Saccharomyces Cerevisiae Extract

Butylene Glycol

Centella Asiatica Flower/Leaf/Stem Extract

Glycine Max Polypeptide

Arginine/Lysine Polypeptide

Copper Tripeptide-1

Disodium EDTA

Acetyl Tetrapeptide-11

Caprylyl Glycol

Acetyl Heptapeptide-4

Sorbic Acid

Hexapeptide-9

Acetyl Hexapeptide-8

Sodium Hydroxide

Acetyl Octapeptide-3

Camellia Sinensis Leaf Water 95%, Water, Propanediol, Glycerin, Niacinamide, 1,2-Hexanediol, Camellia Sinensis Leaf Extract, Ethylhexylglycerin, Adenosine, Dextrin, Ectoin, Hyaluronic Acid, 3-O-Ethyl Ascorbic Acid, Glutathione, Mannitol, Saccharomyces Cerevisiae Extract, Butylene Glycol, Centella Asiatica Flower/Leaf/Stem Extract, Glycine Max Polypeptide, Arginine/Lysine Polypeptide, Copper Tripeptide-1, Disodium EDTA, Acetyl Tetrapeptide-11, Caprylyl Glycol, Acetyl Heptapeptide-4, Sorbic Acid, Hexapeptide-9, Acetyl Hexapeptide-8, Sodium Hydroxide, Acetyl Octapeptide-3

Centella Asiatica Extract

Pentylene Glycol

Betaine

Allantoin

Panthenol

Madecassoside

Xylitylglucoside

Anhydroxylitol

Xylitol

Prunus Mume Fruit Extract

Pyrus Malus Fruit Extract

Carica Papaya Fruit Extract

Vitis Vinifera Fruit Extract

Caprylic/Capric Triglyceride

Glucose

Xanthan Gum

Centella Asiatica Extract, 1,2-Hexanediol, Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Propanediol, Betaine, Allantoin, Panthenol, Madecassoside, Xylitylglucoside, Anhydroxylitol, Xylitol, 3-O-Ethyl Ascorbic Acid, Prunus Mume Fruit Extract, Pyrus Malus Fruit Extract, Carica Papaya Fruit Extract, Vitis Vinifera Fruit Extract, Caprylic/Capric Triglyceride, Water, Glucose, Disodium EDTA, Xanthan Gum, Ethylhexylglycerin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.

Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:

In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.

The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.

A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.

Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).

Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Case Studies and Research

Numerous case studies and research have demonstrated the effectiveness of functional medicine in managing chronic diseases. For example, a study published in the Journal of Clinical Rheumatology found that functional medicine approaches can significantly improve symptoms and quality of life in patients with rheumatoid arthritis. Another study published in the Journal of Alternative and Complementary Medicine found that functional medicine interventions can reduce blood pressure and improve cardiovascular health in patients with hypertension. These studies highlight the importance of functional medicine in addressing the root causes of chronic diseases and promoting optimal health and well-being.

Source: yoodirecthealth.com ↗
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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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